Type your drug name (like Atorvastatin, Sildenafil, etc)
Probenecid / Colchicine Coupon - Probenecid / Colchicine 500mg/0.5mg tablet
Probenecid / ColchicineGeneric Col-Probenemid, Proben-C, Colbenemid
COLCHICINE; PROBENECID is for joint pain and swelling due to gouty arthritis. The lowest GoodRx price for the most common version of probenecid / colchicine is around $22.00, 66% off the average retail price of $64.88. Compare uricosuric / colchicum alkaloid combinations.
Prescription Settings
probenecid / colchicine(generic)
60 tablets
Probenecid / Colchicine Coupon - Probenecid / Colchicine 500mg/0.5mg tablet
probenecid / colchicine(generic)
60 tablets

Probenecid / Colchicine Side Effects

What should I watch for?

Visit your doctor or health care professional for regular checks on your progress. You may need periodic blood checks.

Aspirin and non-steroidal antiinflammatory drugs like ibuprofen can make this medicine less effective. Do not treat yourself for headaches or pain. Ask your doctor or health care professional for advice.

Alcohol can increase the chance of getting stomach problems and gout attacks. Do not drink alcohol.

You may need to be on a special diet while taking this medicine. Check with your doctor. Also, ask how many glasses of fluid you need to drink a day. You must not get dehydrated.

This medicine may cause a decrease in vitamin B12. You should make sure that you get enough vitamin B12 while you are taking this medicine. Discuss the foods you eat and the vitamins you take with your health care professional.

This medicine can interfere with some urine glucose tests. If you use such tests talk with your health care professional.


Common and Rare Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:


Fast or irregular breathing

puffiness or swelling of the eyelids or around the eyes

shortness of breath, troubled breathing, tightness in chest, or wheezing

changes in the skin color of the face occurring together with any of the other side effects listed here

or skin rash, hives, or itching occurring together with any of the other side effects listed here

Check with your doctor immediately if any of the following side effects occur:

Symptoms of overdose

Bloody urine

burning feeling in stomach, throat, or skin

convulsions (seizures)

diarrhea (severe or bloody)


mood or mental changes

muscle weakness (severe)

nausea or vomiting (severe and continuing)

sudden decrease in amount of urine

troubled or difficult breathing

Check with your doctor as soon as possible if any of the following side effects occur:

Less common

Difficult or painful urination

lower back or side pain (especially if severe or sharp)

skin rash, hives, or itching (occurring without other signs of an allergic reaction)


Black or tarry stools

cloudy urine

cough or hoarseness

fast or irregular breathing

numbness, tingling, pain, or weakness in hands or feet

pinpoint red spots on skin

sores, ulcers, or white spots on lips or in mouth

sore throat, fever, and chills

sudden decrease in the amount of urine

swelling of face, fingers, feet, and/or lower legs

swollen and/or painful glands

unusual bleeding or bruising

unusual tiredness or weakness

yellow eyes or skin

weight gain

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Diarrhea (mild)


loss of appetite

nausea or vomiting (mild)

stomach pain

Less common


flushing or redness of face (occurring without any signs of an allergic reaction)

frequent urge to urinate

sore gums

unusual loss of hair

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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