The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
Probenecid
- Headache
- Dizziness
- Sudden gout attack (sharp pain and swelling at the joints)
- Nausea
- Vomiting
- Kidney stones
- Nerve pain
- Muscle weakness
- Nausea
- Vomiting
- Diarrhea
Less Common Side Effects
- Hair loss
- Flushing
- Itching
Probenecid/Colchicine serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Severe allergic reaction: facial swelling, anaphylaxis (e.g., closing of the throat), trouble breathing
- Kidney stones: severe back pain, stomach pain, blood in your urine, fever, chills
- Low blood cell counts: fever, trouble breathing, chills, weakness, unusual bruising or bleeding, blood in urine or stool
Source: DailyMed
The following Probenecid/Colchicine side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Rare
Fast or irregular breathing
puffiness or swelling of the eyelids or around the eyes
shortness of breath, troubled breathing, tightness in chest, or wheezing
changes in the skin color of the face occurring together with any of the other side effects listed here
or skin rash, hives, or itching occurring together with any of the other side effects listed here
Check with your doctor immediately if any of the following side effects occur:
Check with your doctor as soon as possible if any of the following side effects occur:
Less common
Difficult or painful urination
lower back or side pain (especially if severe or sharp)
skin rash, hives, or itching (occurring without other signs of an allergic reaction)
Rare
Black or tarry stools
cloudy urine
cough or hoarseness
fast or irregular breathing
numbness, tingling, pain, or weakness in hands or feet
pinpoint red spots on skin
sores, ulcers, or white spots on lips or in mouth
sore throat, fever, and chills
sudden decrease in the amount of urine
swelling of face, fingers, feet, and/or lower legs
swollen and/or painful glands
unusual bleeding or bruising
unusual tiredness or weakness
yellow eyes or skin
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common
Dizziness
flushing or redness of face (occurring without any signs of an allergic reaction)
frequent urge to urinate
sore gums
unusual loss of hair
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
