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Picato

ingenol mebutate
Used for Actinic Keratosis
Used for Actinic Keratosis

Picato (ingenol mebutate) was a medication used for actinic keratosis. It was a gel that was applied directly on the skin. It has been discontinued in the United States because it's linked to higher a risk of skin cancer.

Reviewed by:
reviewer
Robert Chad Hakim, PharmD, BCCCP
reviewer
Connie Zheng, PharmD
Last reviewed on April 25, 2022
BasicsFAQsInteractionsPricesMedicare
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What is Picato (ingenol mebutate)?

How Picato (ingenol mebutate) works

Drug Facts

Common BrandsPicato
Drug ClassTopical gel
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityPrescription only
faqs

Frequently asked questions about Picato (ingenol mebutate)

What is Picato (ingenol mebutate)?
Picato (ingenol mebutate) is a medication used directly on the skin to treat a condition called actinic keratosis (AK). AK is where your skin cells grow faster than normal. It results from too much exposure to ultraviolet (UV) light from the sun or tanning beds. People with AK might notice symptoms such as rough and scaly patches, rough pimple-like bumps, or raised pink or gray patches on their skin. If left untreated, AK can develop into skin cancer. Picato (ingenol mebutate) works by killing the cells that form these patches or bumps, although the exact way that it does this known.
Is Picato (ingenol mebutate) still available?
No, Picato (ingenol mebutate) has been discontinued and is no longer available in the United States.
Why was Picato (ingenol mebutate) discontinued?
Picato (ingenol mebutate) was discontinued by the manufacturer because it was found to potentially raise the risk of skin cancer. If you currently have Picato (ingenol mebutate), you're recommended to stop using it and contact your provider for other available treatment options.
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interactions

Interactions between Picato (ingenol mebutate) and other drugs

Picato (ingenol mebutate) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Picato (ingenol mebutate). Please note that only the generic name of each medication is listed below.

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

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