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Odactra

Odactra Side Effects

Kristianne Hannemann, PharmDAllison Gourley, PharmD
Reviewed by Kristianne Hannemann, PharmD, Allison Gourley, PharmD
Last reviewed on February 27, 2025

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

Adults 18 to 65 years old:

  • Irritation or tickle in the throat (67%)
  • Itchy mouth (61%)
  • Itchy ear (52%)
  • Swelling in the back of the mouth (20%)
  • Swelling of the lips (18%)
  • Swelling of the tongue (16%)
  • Nausea (14%)
  • Throat swelling (14%)
  • Tongue pain (14%)
  • Sore on the tongue (12%)
  • Stomach pain (11%)
  • Mouth sore (10%)
  • Changes in taste (10%)

Children 12 to 17 years old:

  • Irritation or tickle in the throat (73%)
  • Itchy mouth (73%)
  • Itchy ear (50%)
  • Tongue pain (25%)
  • Stomach pain (23%)
  • Swelling in the back of the mouth (20%)
  • Swelling of the lips (20%)
  • Swelling of the tongue (19%)
  • Swelling of the throat (18%)
  • Nausea (17%)
  • Sore on the tongue (13%)
  • Mouth sore (11%)

Children 5 to 11 years old:

  • Itchy mouth (57%)
  • Itchy ear (33%)
  • Stomach pain (28%)
  • Swelling of the lips (21%)
  • Tongue pain (19%)
  • Nausea (16%)
  • Swelling in the back of the mouth (14%)
  • Swelling of the tongue (14%)
  • Mouth sore (10%)

Less Common Side Effects

  • Itchy tongue
  • Pain in the mouth
  • Tingling in the mouth
  • Upset stomach
  • Diarrhea
  • Vomiting

Odactra serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Serious allergic reaction: trouble breathing, throat swelling or tightness, chest tightness, swelling of your lips or tongue, dizziness, fainting, fast heartbeat, rash, flushing or itching of the skin, stomach pain or cramps, vomiting, diarrhea
When do Odactra possible side effects begin and end?
Time passed since treatment started:
M
H
D
W
M
Irritation or tickle in the throat
Itchy mouth
Itchy ear
Tongue pain
Nausea
Risk of severe allergic reaction
Seek immediate medical care if you experience this side effect.
If a line continues to the right, you'll likely keep experiencing this side effect once it starts.

Source: DailyMed

The following Odactra side effects have also been reported

Side effects that you should report to your care team as soon as possible:

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

  • Burning or tingling of the tongue, mouth, throat, or face
  • Irritation inside the mouth or throat
  • Itching of the mouth, lips, tongue, or ears
  • Mild swelling of the mouth, lips, tongue, or throat
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