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Nexletol Dosages for Adults: Your GoodRx Guide

Stacia Woodcock, PharmDAustin Ulrich, PharmD, BCACP
Published on May 13, 2024

Key takeaways:

  • Nexletol (bempedoic acid) is a medication that helps lower high cholesterol levels. The recommended Nexletol dosage is 180 mg (1 tablet) by mouth daily.

  • You can take Nexletol with or without food, and it doesn’t matter what time of day you take it. But being consistent with when and how you take Nexletol can help you remember to take it and avoid missed doses.

  • There are ways to save on Nexletol. GoodRx can help you access Nexletol at an exclusive cash price of $231. A manufacturer savings card is also available.

An older woman is taking her daily medication.
aquaArts studio/E+ via Getty Images

Nexletol (bempedoic acid) is a medication that helps lower high cholesterol levels. You may take Nexletol if you’re unable to take statins or can’t tolerate their side effects. Or your prescriber may recommend Nexletol if your cholesterol levels are higher than they should be with a statin.

Regardless of why you’re taking Nexletol, it’s helpful to know more about the recommended dosage and how to take the medication. This can ensure you’re getting the most from Nexletol.  

What’s the typical Nexletol dosage for adults?

The recommended Nexletol dosage is 180 mg (1 tablet) by mouth daily. You can take it with or without food, and you can take it at any time of day. But being consistent with when and how you take Nexletol can help you avoid missed doses.

It’s recommended that your prescriber check your cholesterol levels 8 to 12 weeks after you start taking Nexletol. This will help them see how well the medication is working for you and make any adjustments if needed.

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  • Firsthand accounts: Curious what it feels like to take a statin? Three people share their experiences with taking Lipitor for high cholesterol.

Are there any dosage adjustments for Nexletol?

Sometimes, liver or kidney problems can change how a medication is absorbed or broken down by the body. If this happens, you may need a different dosage of the medication to ensure your levels stay in a safe range. But this isn’t the case with Nexletol. The recommended daily dose is the same even if you’re living with liver or kidney problems.

Dosage adjustments of other medications with Nexletol

Nexletol can raise levels of simvastatin (Zocor) and pravastatin (Pravachol) in the body. This can raise your risk of statin-related side effects, such as muscle pain. If you need to take one of these statins with Nexletol, your Nexletol dosage will stay the same. But your simvastatin dosage shouldn’t be over 20 mg daily. And your pravastatin dosage shouldn’t be more than 40 mg daily. 

What happens if you miss a dose of Nexletol?

If you miss a dose of Nexletol, take it as soon as you remember. If it’s close to time for your next dose, skip the missed one and proceed with your usual medication schedule. Don’t take two doses to make up for one you missed.

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If you’re finding it hard to remember to take your medication, consider a medication reminder app or place the bottle somewhere you’re likely to see it every day, such as your bedside table or kitchen counter. 

What should you do if you take too much Nexletol?

We don’t know for sure what the risks are of taking more Nexletol than recommended. It’s possible that you may just have a higher risk of side effects such as nausea and diarrhea. But you could also raise your risk of more serious side effects, such as liver problems and low blood cell counts.

If you or a loved one takes more Nexletol than prescribed, it’s best to contact your prescriber or reach out to Poison Control at 1-800-222-1222 or online. If you have any symptoms that seem life-threatening, seek emergency care.

How to save on Nexletol

There are ways to save on Nexletol, which is available as a brand-name medication. GoodRx can help you navigate between GoodRx coupons and copay savings cards to save money on your prescription.

  • Save with GoodRx: Anyone with a valid prescription, regardless of insurance status, can use GoodRx to purchase a 30-day supply of Nexletol at an exclusive cash price of $231.

  • Save with a copay savings card: If you have commercial insurance, you may be eligible to pay as little as $10 per month for Nexletol using a savings card from the manufacturer.

The bottom line

Nexletol (bempedoic acid) is a medication that helps lower high cholesterol levels. The recommended Nexletol dosage is 180 mg (1 tablet) daily. 

You can take Nexletol on its own if you’re unable to take statins. Or you can take Nexletol along with a statin if your cholesterol levels aren’t low enough with a statin alone. Regardless of why you’re taking Nexletol, the recommended dosage stays the same.

You don’t need a different Nexletol dosage if you have liver or kidney problems. But there are limits to how much simvastatin (Zocor) or pravastatin (Pravachol) you can take with Nexletol. This helps reduce the risk of statin-related side effects.

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Why trust our experts?

Stacia Woodcock, PharmD
Stacia Woodcock, PharmD, is a pharmacy editor for GoodRx. She earned her Doctor of Pharmacy degree from the University of Kentucky and is licensed in New York and Massachusetts.
Austin Ulrich, PharmD, BCACP
Austin Ulrich, PharmD, BCACP, is a board-certified ambulatory care clinical pharmacist. In his early career, he provided direct patient care in a variety of settings, including hospital and community pharmacies, and in a primary care clinic as a clinical pharmacist.

References

Esperion Therapeutics, Inc. (2024). Nexletol - bempedoic acid tablet, film coated [package insert]

MedlinePlus. (2020). Bempedoic acid.

GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.

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