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Guaifenesin DM Coupon - Guaifenesin DM 100mg/10mg/5ml syrup

guaifenesin dm

Generic Mucinex DM
Used for Cough
Used for Cough

Mucinex DM (guaifenesin / dextromethorphan) is an over-the-counter medication that's used to relieve cough and loosen mucus. It has two active ingredients: guaifenesin (an expectorant that clears chest congestion) and dextromethorphan (a cough suppressant that relieves cough). The medication is available as tablets, dissolvable granules, and liquid that are taken by mouth, each with different dosages, directions, and age limits. Extended-release tablets are taken every 12 hours, while the other forms are usually taken every 4 hours. Most people have few to no side effects when used as directed, but it can sometimes cause stomach upset, dizziness, and drowsiness.

Reviewed by:
reviewer
Ally Tsai, PharmD
reviewer
Cydnee Ng, PharmD
Last reviewed on October 22, 2023
BasicsSide effectsPros & consPharmacist tipsFAQsWarningsDosageReviewsCostContraindicationsAlternativesLatest newsImagesReferencesPricesMedicare
basics-icon

What is Mucinex DM (guaifenesin / dextromethorphan)?

What is Mucinex DM (guaifenesin / dextromethorphan) used for?

  • Short-term relief of coughs caused by minor throat or lung irritation (e.g., common cold)

  • Loosens and breaks up mucus in the airways (chest congestion)

How Mucinex DM (guaifenesin / dextromethorphan) works

Mucinex DM (guaifenesin / dextromethorphan) is a combination of two medications.

  • Guaifenesin is an expectorant. It loosens mucus in your airways by making it thinner. This makes it easier to cough out mucus and help clear chest congestion.

  • Dextromethorphan is an antitussive medication, which is another name for a cough suppressant. It works on the part of your brain that makes you cough (your cough reflex). Its actions on the brain make you cough less.

Are you looking for information on guaifenesin (Mucinex) or dextromethorphan (Delsym) instead?
When does Mucinex DM (guaifenesin / dextromethorphan) start working?
Time passed since treatment started:
MINUTES
HOURS
DAYS
WEEKS
MONTHS
Initial effect
Full effect

Drug Facts

Common BrandsMucinex DM, Adult Tussin Cough and Congestion DM, Robitussin Cough and Chest Congestion DM
Drug ClassExpectorant / Antitussive
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityOver-the-counter

More on Mucinex DM (guaifenesin / dextromethorphan) essentials

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What are the side effects of Mucinex DM (guaifenesin / dextromethorphan)?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Side effects aren't common. See Other Side Effects.

Other Side Effects

Possible guaifenesin side effects:
  • Nausea
  • Diarrhea
  • Dizziness
  • Headache
Possible dextromethorphan side effects:
  • Belly discomfort
  • Vomiting
  • Constipation
  • Drowsiness
  • Trouble breathing
  • Racing heart

Serious Side Effects

Contact your healthcare provider immediately if you experience any of the following.
  • Serotonin syndrome: fast heart rate, sweating, muscle stiffness or spasms, high fever, confusion
  • Accidentally taking too much (overdose): feeling "high," hallucinations, fast heartbeat, slow breathing, seizures

Source: DailyMed

The following side effects have also been reported

Side effects that you should report to your care team as soon as possible:

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

pros-and-cons

Pros and cons of Mucinex DM (guaifenesin / dextromethorphan)

thumbs-up

Pros

Available as a tablet, oral liquid, and dissolvable granules

Available over the counter without a prescription

Sugar-free options available, so okay to use for people with high blood sugar

Works within 30 minutes to help lessen cough

thumbs-down

Cons

Not meant to be used long-term

Might need to take multiple times a day to relieve symptoms

Many states require you to be over 18 to buy it because of risk of misuse

Can't cut or crush extended-release tablets

pharmacist-tips

Pharmacist tips for Mucinex DM (guaifenesin / dextromethorphan)

pharmacist

  • Tell your provider if you have a long-lasting cough that's caused by cigarette smoke or bronchitis, a cough that's linked to a breathing problem (e.g., asthma, emphysema), or a cough with a lot of mucus. Mucinex DM (guaifenesin / dextromethorphan) might not be appropriate for these type of coughs.

    • Please talk with your provider if your cough gets worse, comes back after clearing up, or lasts more than a week. Also let them know if you also have rash, fever, or headache. These might be signs of a more serious medical condition that can't be treated with Mucinex DM (guaifenesin / dextromethorphan).

      • For the extended-release tablets: Swallow the tablets whole with a full glass of water. Don't crush, break, or chew the tablets since it can change how the medication works.

        • For the oral liquids, solutions, and syrups: Be sure to use the medication dose cup, spoon, or oral syringe that comes in the packaging to measure out your child's dose. Ask your pharmacy if you need extras. Don't use household spoons because they might not be accurate. Using household spoons might cause your child to take the wrong amount of Mucinex DM (guaifenesin / dextromethorphan).

          • For the dissolvable granules: Pour the entire contents of packet onto the tongue and swallow. Make sure you don't chew or crunch the granules because doing so can change how the medication tastes.

            • Don't give Mucinex DM (guaifenesin / dextromethorphan) to toddlers to take without speaking to a provider because the medication can cause serious side effects in young children. Some safer options include using a clean humidifier or cool mist vaporizer or giving your toddler ice chips or popsicles to suck on to soothe a sore throat.

              • Guaifenesin and dextromethorphan can be found in many over-the-counter medications, so make sure you read package labels carefully. Don't use multiple products with these ingredients. In particular, taking too much dextromethorphan can cause serious side effects, such as fast heartbeat, slow breathing, confusion, or seizures.

                • Keep Mucinex DM (guaifenesin / dextromethorphan) up and away and out of children's reach and sight. Always put medication away every time you use it. This prevents children from accidentally swallowing any medication that was left out. Call a Poison Center at 1-800-222-1222 right away if your child might’ve accidentally swallowed the medication, even if you aren't completely sure.

                  More on Mucinex DM (guaifenesin / dextromethorphan) tips

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                  faqs

                  Frequently asked questions about Mucinex DM (guaifenesin / dextromethorphan)

                  Does Mucinex DM (guaifenesin / dextromethorphan) make you sleepy or drowsy?
                  Though uncommon, it's possible for Mucinex DM (guaifenesin / dextromethorphan) to make you drowsy. Avoid drinking alcohol while you're take Mucinex DM (guaifenesin / dextromethorphan) because it can make you feel even drowsier, which can lead to accidental injuries. Don't drive a car or operate machinery until you know how this medication affects you.
                  Is Mucinex DM (guaifenesin / dextromethorphan) for day or night?
                  You can take Mucinex DM (guaifenesin / dextromethorphan) during the day or at night. But because this medication can sometimes cause drowsiness and dizziness, make sure to avoid activities that require alertness until you find out how it affects you. In addition, the extended-release tablets last for about 12 hours, so you'll typically take it once during the day and once at night. But the other formulations (e.g., oral solution, oral granules) typically last only 4 hours, so you might need to take it multiple times throughout the day and night for symptom relief. Talk to your provider or pharmacist if you need help figuring out which formulation best fits your needs.
                  How many Mucinex DM (guaifenesin / dextromethorphan) can I take each day?
                  Different formulations of Mucinex DM (guaifenesin / dextromethorphan) have different directions, strengths, and dosage limits. Make sure you're taking this medication correctly by following the product instructions on the package. If you're not sure, ask your provider or pharmacist about how much medication you can take per day. For Mucinex DM (guaifenesin / dextromethorphan) extended-release, regular-strength tablets, people 12 years and older can take 1 or 2 tablets by mouth every 12 hours; don't take more than 4 tablets in a 24-hour period. For Mucinex DM (guaifenesin / dextromethorphan) extended-release, maximum-strength tablets, people 12 years and older can take 1 tablet by mouth every 12 hours; don't take more than 2 tablets in a 24-hour period.
                  How often can you take Mucinex DM (guaifenesin / dextromethorphan)?
                  You can take the extended-release tablets every 12 hours as needed for cough and chest congestion. For most other formulations (e.g., oral solution, oral granules), you can take the medication every 4 hours on an as-needed basis if you have cough or chest congestion. Make sure you follow the product instructions on the package or talk with your provider or pharmacist about how often you can use your medication.
                  What does "DM" mean on Mucinex DM?
                  The "DM" on Mucinex DM products stands for dextromethorphan, which is a cough suppressant. It works to lessen cough by blocking your cough reflex. Mucinex DM contains dextromethorphan and another ingredient called guaifenesin, which helps relieve cough. Note that Mucinex DM is different than Mucinex D. Mucinex D contains guaifenesin and pseudoephedrine, a decongestant that relieves stuffy nose.
                  Is Mucinex DM (guaifenesin / dextromethorphan) safe during pregnancy?
                  Speak with your provider about the risks and benefits of taking Mucinex DM (guaifenesin / dextromethorphan) for your cough during pregnancy. Mucinex DM contains two ingredients, dextromethorphan and guaifenesin. Although some studies didn't find a link between using dextromethorphan and birth defects, there aren't many studies on the use of guaifenesin during pregnancy. To be safe, it's best to avoid taking Mucinex DM (guaifenesin / dextromethorphan) in your first trimester. Ask your provider or pharmacist about safe options to relieve your cough if you're pregnant.
                  Can you take Mucinex DM (guaifenesin / dextromethorphan) and Nyquil together?
                  You shouldn't take Mucinex DM (guaifenesin / dextromethorphan) with Nyquil. Most products under the brand Nyquil contain dextromethorphan, which is one of the active ingredients in Mucinex DM (guaifenesin / dextromethorphan). Taking too much dextromethorphan can lead to overdose symptoms, such as feeling "high," hallucinations, fast heartbeat, slow breathing, and seizures. Keep in mind that many over-the-counter cough, cold, and flu medications contain similar ingredients, and it's best to avoid taking medications with overlapping ingredients. Always check with your provider or pharmacist before taking multiple over-the-counter cough, cold, and flu medications to make sure they're safe for you to take together.
                  Can you take ibuprofen or Tylenol with Mucinex DM (guaifenesin / dextromethorphan)?
                  Yes, it's generally considered safe to take ibuprofen (Advil) or acetaminophen (Tylenol)) with Mucinex DM (guaifenesin / dextromethorphan). These medications contain different ingredients and relieve different symptoms of cold and flu. Ibuprofen (Advil) and acetaminophen (Tylenol) are used to relieve pain and fever. And Mucinex DM (guaifenesin / dextromethorphan) is used to soothe cough and chest congestion. Keep in mind that these pain relievers have risks as well. Ibuprofen (Advil) has heart risks and can cause kidney problems, and acetaminophen (Tylenol) has a risk for liver damage. Before taking over-the-counter cold or flu medications, speak with your provider to make sure it's safe for you to do so.
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                  What are the risks and warnings for Mucinex DM (guaifenesin / dextromethorphan)?

                  Mucinex DM (guaifenesin / dextromethorphan) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

                  risk-warning

                  Risk of overdose and misuse

                  • Risk factors: Taking with other similar medications

                    Mucinex DM (guaifenesin / dextromethorphan) contains two common ingredients that are found in many other over-the-counter products. Using more than one product with the same ingredients can lead to an accidental overdose that can be dangerous. In addition, some people might misuse dextromethorphan on purpose, which can lead to poisoning, especially if it's taken at high doses. This is why many retail stores require you to be over 18 years old to purchase products containing dextromethorphan.

                    Talk to your provider or pharmacist before you start Mucinex DM (guaifenesin / dextromethorphan) if you're not sure whether you're already taking a medication that has dextromethorphan or guaifenesin in it. To prevent an accidental overdose, carefully follow the product instructions on the package.

                    Call your Poison Control Center at 1-800-222-1222 right away if you or anyone else might’ve accidentally taken too much Mucinex DM (guaifenesin / dextromethorphan), even if you aren't completely sure. Also call the Poison Control Center or get medical help if you or someone else has trouble breathing, hallucinations, or changes in behavior after taking the medication because these can be signs that someone's taken too much.

                    risk-warning

                    Interactions with certain medications for Parkinson's disease and depression

                    Talk to your provider first before using Mucinex DM (guaifenesin / dextromethorphan) if you're taking or have recently taken medications for Parkinson's disease or depression known as monoamine oxidase inhibitors (MAOIs). These medications can interact with Mucinex DM (guaifenesin / dextromethorphan) and cause dangerously high blood pressure. This drug interaction can also lead to a rare, but serious side effect called serotonin syndrome. Ask your provider about other options to relieve your cough symptoms if you've taken these medications in the past two weeks.

                    risk-warning

                    Caution use in people with phenylketonuria (PKU) - dissolvable granules only

                    The dissolvable granule formulation of Mucinex DM (guaifenesin / dextromethorphan) contain phenylalanine, a sweetener that's often added to medications. Phenylalanine is harmless to most people. But it can be dangerous to people with an inherited medical condition called phenylketonuria (PKU). Avoid using the dissolvable granules if you or your child has a history of PKU. Consider using the oral solution or tablet, which don't contain phenylalanine. Talk to a provider if you're not sure which products contain phenylalanine and which products are safer options before using any over-the-counter products.

                    dosage

                    Mucinex DM (guaifenesin / dextromethorphan) dosage forms

                    The average cost for 118 ml of 100mg/10mg/5ml of Mucinex DM (guaifenesin / dextromethorphan) is $4.28 with a free GoodRx coupon. This is 53.23% off the average retail price of $9.15.
                    capsule
                    Capsule
                    DosageQuantityPrice as low asPrice per unit
                    200mg/10mg40 capsules$5.65$0.14
                    ml of oral solution
                    Ml of oral solution
                    DosageQuantityPrice as low asPrice per unit
                    200mg/10mg/5ml473 ml$11.73$0.02
                    200mg/20mg/10ml118 ml$3.77$0.03
                    200mg/20mg/20ml118 ml$4.89$0.04
                    400mg/20mg/20ml118 ml$4.67$0.04
                    ml of syrup
                    Ml of syrup
                    DosageQuantityPrice as low asPrice per unit
                    100mg/10mg/5ml118 ml$4.28$0.04
                    tablet
                    Tablet
                    DosageQuantityPrice as low asPrice per unit
                    400mg/20mg30 tablets$4.54$0.15
                    600mg/30mg20 tablets$9.73$0.49
                    1200mg/60mg14 tablets$6.58$0.47

                    Typical dosing for Mucinex DM (guaifenesin / dextromethorphan)

                    This medication is made by many different manufacturers in different formulations. These formulations can have different directions and strengths.

                    Follow the specific product instructions on the package or talk with your provider or pharmacist about how to take this medication correctly. Some examples are listed below:

                    Extended-release tablets

                    • Regular strength (Mucinex DM and generic): Each tablet contains 600 mg of guaifenesin and 30 mg of dextromethorphan.

                      • People 12 years and older: The typical dose is 1 or 2 tablets by mouth every 12 hours. Don't take more than 4 tablets in a 24-hour period.

                      • Children under age 12: Don't use. Ask your child's provider for other options.

                    • Maximum strength (Mucinex DM Maximum Strength and generic): Each tablet contains 1,200 mg of guaifenesin and 60 mg of dextromethorphan.

                      • People 12 years and older: The typical dose is 1 tablet by mouth every 12 hours. Don't take more than 2 tablets in a 24-hour period.

                      • Children under age 12: Don't use. Ask your child's provider for other options.

                    Oral liquids

                    • Children’s Robitussin Cough and Chest Congestion DM: Each teaspoon (5 mL) contains 50 mg of guaifenesin and 5 mg of dextromethorphan. Don't take more than 6 doses in a 24-hour period.

                      • People 12 years and older: The typical dose is 20 mL by mouth every 4 hours.

                      • Children 6 to 12 years: The typical dose is 10 mL by mouth every 4 hours.

                      • Children 4 to 6 years: The typical dose is 5 mL by mouth every 4 hours.

                      • Children under age 4: Don't use. Ask your child's provider for other options.

                    Oral granules

                    • Mucinex Children's Cough and Chest Congestion Mini-Melts: Each packet contains 100 mg of guaifenesin and 5 mg of dextromethorphan. Don't take more than 6 doses in a 24-hour period.

                      • People 12 years and older: The typical dose is 2 to 4 packets by mouth every 4 hours.

                      • Children 6 to 12 years: The typical dose is 1 to 2 packets by mouth every 4 hours.

                      • Children 4 to 6 years: The typical dose is 1 packet by mouth every 4 hours.

                      • Children under age 4: Don't use. Ask your child's provider for other options.

                    More on Mucinex DM (guaifenesin / dextromethorphan) dosage forms

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                    Mucinex DM Dosages: Your GoodRx Guide

                    Written by Sarah Morin, RPh
                    Reviews

                    Mucinex DM (guaifenesin / dextromethorphan) Reviews

                    GoodRx has partnered with PatientsLikeMe to provide reviews on the different aspects of Mucinex DM (guaifenesin / dextromethorphan).

                    Effectiveness

                    Learn more about the effectiveness of Mucinex DM (guaifenesin / dextromethorphan) based on real life experiences.

                    Overall Rating

                    Based on 2 people taking this medication

                    1.3

                    Effectiveness by condition:

                    fibromyalgia2 reviews

                    1.3

                    Side effects
                    Learn more about the side effects others have reported while taking Mucinex DM (guaifenesin / dextromethorphan).

                    Severity of side effects

                    Based on 19 people taking this medication

                    None

                    69%

                    Mild

                    32%

                    Moderate

                    0%

                    Severe

                    0%

                    0%

                    50%

                    100%

                    Top side effects

                    Based on 19 people taking this medication

                    Sleepiness

                    11%

                    Fatigue

                    6%

                    Nausea

                    6%

                    Restlessness (akathisia)

                    6%

                    Usage
                    Review why people stop taking this medication and how long they take it.

                    Reasons people stopped taking Mucinex DM (guaifenesin / dextromethorphan)

                    Based on 20 people who have taken this medication

                    Course of treatment ended

                    60%

                    Did not seem to work

                    15%

                    Doctor's advice

                    10%

                    Other

                    10%

                    Personal research

                    5%

                    How long people take Mucinex DM (guaifenesin / dextromethorphan)

                    Based on 27 people taking this medication

                    2 to <5 years

                    4%

                    5 to <10 years

                    30%

                    10+ years

                    67%

                    0%

                    50%

                    100%

                    Powered by:Patients Like Me logo
                    drug-cost

                    How much does Mucinex DM (guaifenesin / dextromethorphan) cost?

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                    Mucinex DM (guaifenesin / dextromethorphan) (generic)
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                    contraindications-icon

                    Mucinex DM (guaifenesin / dextromethorphan) contraindications

                    Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Mucinex DM (guaifenesin / dextromethorphan) will not be safe for you to take.
                    alternatives

                    What are alternatives to Mucinex DM (guaifenesin / dextromethorphan)?

                    There are a number of medications that your doctor can prescribe in place of Mucinex DM (guaifenesin / dextromethorphan). Compare a few possible alternatives below.
                    Mucinex DM (guaifenesin / dextromethorphan)
                    Used for:

                    • Short-term relief of coughs caused by minor throat or lung irritation (e.g., common cold)

                    • Loosens and breaks up mucus in the airways (chest congestion)

                    $3.77 Lowest GoodRx priceView Prices
                    Codeine/guaifenesin
                    Used for:

                    • Temporarily easily cough from throat or lung irritations

                    • Loosens mucus so that its easier to cough up

                    $6.25 Lowest GoodRx priceView Prices
                    Benzonatate (Tessalon Perles)
                    Used for:

                    • Cough in people ages 10 years and older

                    $11.31 Lowest GoodRx priceView Prices
                    images

                    Mucinex DM (guaifenesin / dextromethorphan) images

                    White And Yellow Oval 600, Adams, And Mucinex - Mucinex DM 30mg-600mg Extended-Release Tablet
                    This medicine is White And Yellow, Oval Tablet Imprinted With "Adams", "Mucinex", And "600".White And Yellow Oval 600, Adams, And Mucinex - Mucinex DM 30mg-600mg Extended-Release Tablet

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                    References

                    Best studies we found

                    Albrecht, H. H., et al. (2017). Role of guaifenesin in the management of chronic bronchitis and upper respiratory tract infections. Multidisciplinary Respiratory Medicine.

                    Centers for Disease Control and Prevention. (2021). Sore throat.

                    Centers for Disease Control and Prevention. (2023). Put your medicines up and away and out of sight.

                    View All References (16)

                    Dolansky, G., et al. (2008). What is the evidence for the safety and efficacy of over-the-counter cough and cold preparations for children younger than six years of age? Paediatrics & Child Health.

                    Dr. Reddy’s Laboratories Inc. (2023). Guaifenesin and dextromethorphan HBR tablet, extended release [package insert]. DailyMed.

                    Haleon US Holdings LLC. (2024). Childrens Robitussin cough and chest congestion DM- dextromethorphan hydrobromide and guaifenesin liquid [package insert]. DailyMed.

                    Journey, J. D., et al. (2023). Dextromethorphan toxicity. StatPearls.

                    Kroger Company. (2022). Guaifenesin and dextromethorphan HBR- guaifenesin and dextromethorphan hbr tablet, extended release [package insert]. DailyMed.

                    May, M. E. (n.d.). Dextromethorphan abuse. Poison Control.

                    National Human Genome Research Institute. (2014). About phenylketonuria.

                    Oh, S. R., et al. (2023). Dextromethorphan. StatPearls.

                    Proctor & Gamble. (n.d.). Powerful max strength symptom relief.

                    RB Health (US) LLC. (2022). Mucinex childrens  cough and chest congestion mini-melts orange creme- dextromethorphan hydrobromide and guaifenesin granule [package insert]. DailyMed.

                    RB Health (US) LLC. (2022). Mucinex DM- guaifenesin and dextromethorphan hydrobromide tablet, extended release [package insert]. DailyMed.

                    RB Health (US) LLC. (2023). Mucinex DM maximum strength- guaifenesin and dextromethorphan hydrobromide tablet, extended release [package insert]. DailyMed.

                    Siu, A., et al. (2007). Dextromethorphan: A review of N-methyl-D-aspartate receptor antagonist in the management of pain. Central Nervous System Drug Reviews.

                    Spangler, D. C., et al. (2016). Dextromethorphan: A case study on addressing abuse of a safe and effective drug. Substance Abuse Treatment, Prevention, and Policy.

                    Thomas, S. J., et al. (2015). Combination therapy with monoamine oxidase inhibitors and other antidepressants or stimulants: Strategies for the management of treatment-resistant depression. Reviews of Therapeutics.

                    U.S. Food and Drug Administration. (2023). Should you give kids medicine for coughs and colds?

                    GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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