Welcome! You’re in GoodRx for healthcare professionals. Now, you’ll enjoy a streamlined experience created specifically for healthcare professionals.
Minizide
Minizide (prazosin / polythiazide) is a combination medication used to treat high blood pressure. It has been discontinued and is no longer available in the United States.
Last reviewed on June 2, 2022
What is Minizide (prazosin / polythiazide)?
What is Minizide (prazosin / polythiazide) used for?
High blood pressure (hypertension)
How Minizide (prazosin / polythiazide) works
Are you looking for information on prazosin (Minipress) instead?
Drug Facts
Common BrandsMinizide (brand no longer available)
Drug ClassAlpha blocker / Diuretic (water pill)
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityDiscontinued
Frequently asked questions about Minizide (prazosin / polythiazide)
What is Minizide (prazosin / polythiazide)?
Minizide (prazosin / polythiazide) is a medication taken by mouth that's used to lower blood pressure. It's a combination of two medications, prazosin and polythiazide. Prazosin is an alpha blocker, which lowers blood pressure by relaxing blood vessels. Polythiazide is a diuretic (water pill), which lowers blood pressure by lowering the amount of fluid buildup in your body.
Is Minizide (prazosin / polythiazide) still available?
No, Minizide (prazosin / polythiazide) has been discontinued and is no longer available in the United States.
Why was Minizide (prazosin / polythiazide) discontinued?
It's not clear why Minizide (prazosin / polythiazide) was discontinued. Prazosin is still available as a single-ingredient medication (also known as the brand Minipress), which can be used to treat high blood pressure. Polythiazide was available as a single-ingredient medication at one time. But, it has also been discontinued and is no longer available in the United States.
What alternatives can I use instead of Minizide (prazosin / polythiazide)?
There are many medications available that can treat high blood pressure. Prazosin (Minipress) alone is available and can be used to treat high blood pressure, among other conditions. And there are diuretics that are similar to polythiazide (e.g., hydrochlorothiazide (Microzide), chlorothiazide (Diuril)) that can also be used for high blood pressure. In addition, there are other combination products that include two different types of blood pressure medications. Some examples include Zestoretic (lisinopril / hydrochlorothiazide) and Diovan HCT (valsartan / hydrochlorothiazide). These medications might not be appropriate for everyone. Talk to your provider about what the best treatment choice is for you.
How to save using GoodRx
1. Compare PricesSpecify your dosage and quantity to find out exactly how much you can save.
2. Select your free couponYou can use the displayed coupon, or compare prices at other pharmacies near you.
3. Show coupon to your pharmacistPresent your printed or electronic coupon when you pick up your prescription.
What are alternatives to Minizide (prazosin / polythiazide)?
There are a number of medications that your doctor can prescribe in place of Minizide (prazosin / polythiazide). Compare a few possible alternatives below.
Used for:
High blood pressure
Swelling in the body from fluids (edema), in addition to other medications
Get savings updates for Minizide (prazosin / polythiazide)
Receive price alerts, news, and other messages from GoodRx about Minizide (prazosin / polythiazide) and other healthcare topics and relevant savings offers.By signing up, I agree to GoodRx's Terms and Privacy Policy, and to receive marketing messages from GoodRx.
Browse medications
View AllResearch prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.