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Minivelle

Minivelle Side Effects

Kristianne Hannemann, PharmDDaisy Chau, PharmD
Reviewed by Kristianne Hannemann, PharmD, Daisy Chau, PharmD
Last reviewed on March 5, 2025

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Headache (up to 50%)
  • Common cold symptoms (up to 20%)
  • Breast tenderness (up to 17%)
  • Sinus swelling (up to 13%)
  • Bleeding in-between periods (up to 11%)
  • Depression (up to 11%)
  • Back pain (up to 11%)
  • Sinus headache (up to 10%)
  • Indigestion (up to 9%)
  • Weight gain (up to 9%)
  • Joint pain (up to 9%)

Less Common Side Effects

  • Constipation
  • Flu-like symptoms
  • Pain in arms or legs
  • Neck pain
  • Other pain in body
  • Anxiety
  • Trouble sleeping
  • Nausea
  • Vomiting
  • Stomach cramps
  • Migraine
  • Dizziness

Minivelle serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Heart attack: chest pain or tightness, pain that radiates up to your shoulder, arm, neck, or jaw
  • Stroke: sudden trouble talking, trouble walking, numbness on one side of your body or face, severe headache, confusion
  • Deep vein thrombosis (blood clot in the leg): leg cramp, swelling, pain, muscle tightness
  • Pulmonary embolism (blood clot in the lung): cough, chest pain, trouble breathing, racing heart
  • Cancer: lumps, pain, swelling, or changes in the breasts; swollen lymph nodes, unusual or heavy vaginal bleeding, bloating, extreme tiredness, stomach-area pain
  • Gallbladder problems: stomach pain, nausea or vomiting that doesn't go away, fever, yellowing of the skin and eyes (jaundice)
  • Severe allergic reaction: hives, swelling in the face or throat, trouble breathing, stomach pain, vomiting

Source: DailyMed

The following Minivelle side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Incidence not known

Abdominal or stomach cramps or pain

acid or sour stomach

anxiety

backache

belching

blistering, peeling, or loosening of the skin

bloating

blurred vision

breast tenderness, enlargement, pain, or discharge

change in vaginal discharge

changes in skin color

changes in vision

chest pain or discomfort

chills

clay-colored stools

clear or bloody discharge from the nipple

confusion

constipation

convulsions

cough

darkening of the urine

diarrhea

difficulty with breathing

difficulty with swallowing

dimpling of the breast skin

dizziness or lightheadedness

double vision

fainting

fast heartbeat

fever

fluid-filled skin blisters

full or bloated feeling or pressure in the stomach

headache

headache, severe and throbbing

heartburn

indigestion

inverted nipple

irregular heartbeat

itching of the vagina or genital area

joint or muscle pain

large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs

light-colored stools

loss of appetite

loss of bladder control

lump in the breast or under the arm

migraine headache

mood or mental changes

muscle cramps in the hands, arms, feet, legs, or face

muscle spasm or jerking of all extremities

nausea

noisy breathing

numbness and tingling around the mouth, fingertips, or feet

pain during sexual intercourse

pain in the ankles or knees

pain or discomfort in the arms, jaw, back, or neck

pain or feeling of pressure in the pelvis

pain, redness, or swelling in the arm, foot, or leg

painful, red lumps under the skin, mostly on the legs

pains in the stomach, side, or abdomen, possibly radiating to the back

persistent crusting or scaling of the nipple

poor insight and judgment

problems with memory or speech

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

rash, hives, or itching

red, irritated eyes

redness or swelling of the breast

sensitivity to the sun

skin thinness

sore on the skin of the breast that does not heal

sore throat

sores, ulcers, or white spots in the mouth or on the lips

stomach discomfort, upset, or pain

sudden loss of consciousness

sudden shortness of breath or troubled breathing

sweating

swelling

swelling of the abdominal or stomach area

thick, white vaginal discharge with no odor or with a mild odor

tightness in the chest

tremor

trouble recognizing objects

trouble thinking and planning

trouble walking

unexpected or excess milk flow from the breasts

unpleasant breath odor

unusual tiredness or weakness

unusually heavy or unexpected menstrual bleeding

vaginal bleeding or spotting

vomiting

vomiting of blood

yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Back pain

difficulty with moving

muscle aches

muscle pain or stiffness

stuffy or runny nose

Incidence not known

Decreased interest in sexual intercourse

heavy bleeding

hives or welts

inability to have or keep an erection

increased hair growth, especially on the face

increased in sexual ability, desire, drive, or performance

increased interest in sexual intercourse

irritability

leg cramps

loss in sexual ability, desire, drive, or performance

loss of scalp hair

mental depression

mood disturbances

patchy brown or dark brown discoloration of the skin

redness of the skin

twitching, uncontrolled movements of the tongue, lips, face, arms, or legs

weight changes

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Why trust our experts?

Kristianne Hannemann, PharmD, is a licensed pharmacist in California. She has been a retail pharmacy manager and staff pharmacist for over 7 years and has contributed drug information content to different health companies.
Daisy Chau, PharmD
Reviewed by:
Daisy Chau, PharmD
Daisy Chau, PharmD, is the drug information pharmacist manager at GoodRx. She is licensed in California and has more than 6 years of experience working as a pharmacist in drug information.

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