The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Dizziness
- Electrolyte imbalance (low sodium, magnesium, and potassium)
Less Common Side Effects
- Muscle cramps
- Fatigue (feeling very tired)
- High uric acid levels
Metolazone serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Allergic reactions: trouble breathing, rash or hives, swelling in your face, lips, tongue, or throat
- Serious skin reaction: fever, chills, body aches, cough, itchiness, blistering or peeling skin, severe rash
- Electrolyte imbalance: weakness, muscle pain or cramps, dizziness, fast heartbeat, or vomiting
- Kidney problems: fatigue, confusion, swelling in your feet or ankles, or little to no urination
Source: DailyMed
The following Metolazone side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Incidence not known
Black, tarry stools
bleeding gums
blistering, peeling, or loosening of skin
blood in urine or stools
blurred vision
bone pain
chills
clay-colored stools
cold sweats
coma
confusion
convulsions
dark urine
decreased urine
dizziness, faintness, or lightheadedness when getting up from lying or sitting position
drowsiness
fast, irregular, pounding, or racing heartbeat or pulse
flushed, dry skin
fruit-like breath odor
general tiredness and weakness
headache
incoherent speech
increased hunger
increased thirst
increased urination
indigestion
irritability
joint or muscle pain
light-colored stools
loss of appetite
lower back or side pain
metallic taste
mood changes
muscle pain or cramps
numbness or tingling in hands, feet, or lips
pain in lower legs
painful or difficult urination
pinpoint red spots on skin
rash
red irritated eyes
red skin lesions, often with a purple center
redness or swelling of lower leg
shortness of breath
sores, ulcers, or white spots in mouth or on lips
sugar in the urine
sweating
swelling of face, ankles, or hands
swollen or painful glands
tightness in chest
trembling
troubled breathing
unexplained weight loss
unpleasant breath odor
unusual bleeding or bruising
unusual tiredness or weakness
upper right abdominal pain
vomiting of blood
weak pulse
yellow eyes and skin
Get emergency help immediately if any of the following symptoms of overdose occur:
Symptoms of overdose
Fainting
irregular, fast or slow, or shallow breathing
pale or blue lips, fingernails, or skin
unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
weakness and heaviness of legs
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Incidence not known
Blue-green to black skin discoloration
burning, tingling, numbness, or pain in the hands, arms, feet, or legs
cracked, dry, or scaly skin
decreased interest in sexual intercourse
feeling of constant movement of self or surroundings
hives or welts
inability to have or keep an erection
loss in sexual ability, desire, drive, or performance
pain, redness, or sloughing of skin at place of injection
restlessness
sensation of pins and needles
sensation of spinning
stabbing pain
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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