The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Temporary sleepiness
- Temporary headache
- Temporary weakness
- Low blood pressure
- Dizziness
- Sensitivity to light
Less Common Side Effects
- Swelling
- Weight gain
- Slow heart rate
- Nausea
- Vomiting
- Diarrhea
- Dry mouth
- Lightheadedness
- Pins and needles feeling
- Joint or muscle pain
- Stuffy nose
- Rash
- Absent period
- Breast enlargement
- Lower sex drive
Methyldopa/HCTZ serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Electrolyte imbalance: dry mouth, extreme thirst, weakness, tiredness, sleepiness, restlessness, confusion, seizures, muscle pain or cramps, low blood pressure, trouble urinating, irregular heart beat, nausea, or vomiting
- Hemolytic anemia: paleness of skin, dark urine, fever, weakness, confusion, or yellowing of eyes and skin
- Liver damage: unsual vomiting, pale stools, dark urine, stomach pain, or yellowing of the eyes and skin
Source: DailyMed
The following Methyldopa/HCTZ side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Rare
Unexplained fever shortly after starting to take this medicine
Check with your doctor as soon as possible if any of the following side effects occur:
Signs and symptoms of too much potassium loss
increased thirst
irregular heartbeats
muscle cramps or pain
nausea or vomiting
unusual tiredness or weakness
weak pulse
Rare
Cough or hoarseness
dark or amber urine
diarrhea or stomach cramps (severe or continuing)
fever, chills, troubled breathing, and fast heartbeat
general feeling of discomfort or illness or weakness
joint pain
lower back or side pain
painful or difficult urination
pale stools
stomach pain (severe) with nausea and vomiting
tiredness or weakness after having taken this medicine for several weeks (continuing)
yellow eyes or skin
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Dizziness or light-headedness when getting up from a lying or sitting position
drowsiness
dryness of mouth
headache
Less common
Decreased sexual ability or interest in sex
increased sensitivity of skin to sunlight (skin rash, itching, redness or other discoloration of skin or severe sunburn after exposure to sunlight)
loss of appetite
numbness, tingling, pain, or weakness in hands or feet
slow heartbeat
swelling of breasts or unusual milk production
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
