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Methadone

Methadone Dosage

Robert Chad Hakim, PharmD, BCCCPAllison Gourley, PharmD
Reviewed by Robert Chad Hakim, PharmD, BCCCP, Allison Gourley, PharmD
Last reviewed on June 3, 2024

The average cost for 90 tablets of 10mg of Methadone is $22.37 with a free GoodRx coupon. This is 59.59% off the average retail price of $55.36.

ml of oral solutionMl of oral solution

Dosage

Quantity

Price as low as

Price per unit

5mg/5ml

150 ml

$12.99

$0.09

10mg/5ml

30 ml

$8.22

$0.27

tabletTablet

Dosage

Quantity

Price as low as

Price per unit

5mg

90 tablets

$14.27

$0.16

10mg

90 tablets

$22.37

$0.25

40mg

4 tablets

$6.32

$1.58

ml of oral concentrateMl of oral concentrate

Dosage

Quantity

Price as low as

Price per unit

10mg/ml

90 ml

$23.88

$0.27

dropperDropper

Dosage

Quantity

Price as low as

Price per unit

30ml of 10mg/ml

1 dropper

$13.99

$13.99

Typical dosage for Methadone

In general, your dose will depend on why you need methadone, how severe your symptoms are, and whether you're taking other opioids. Your prescriber will work closely with you to adjust your dose based on your individual needs. It's recommended to take the smallest amount of methadone necessary to manage your condition for the shortest period of time possible.

  • Long-term pain

    • If you're not already taking an opioid: The typical starting dose of methadone is 2.5 mg by mouth every 8 to 12 hours.
    • If you're switching from another opioid to methadone: Your prescriber will calculate your methadone dose based on the dose of the opioid you were taking. Methadone is taken by mouth, as directed by your prescriber.
  • Opioid use disorder (OUD)

    • Methadone is typically started in a healthcare setting (e.g., methadone clinic) under the direct supervision by a healthcare professional (HCP).
    • The typical starting dose is 20 mg to 30 mg by mouth at the first sign of opioid withdrawal. The HCP will observe you at the clinic for 2 to 4 hours and they might give you an additional 5 mg to 10 mg if your withdrawal symptoms haven't improved. The maximum dose on the first day of treatment is 40 mg.

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