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Dexamethasone

Dexamethasone Side Effects

Robert Chad Hakim, PharmD, BCCCPKristianne Hannemann, PharmD
Reviewed by Robert Chad Hakim, PharmD, BCCCP, Kristianne Hannemann, PharmD
Last reviewed on March 14, 2023

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

When used for eye inflammation:

  • Eye discomfort (10%)
  • Eye irritation (1%)

Less Common Side Effects

When used for eye inflammation:

  • Dry eye
  • Blurred vision
  • Itchy eye
  • Feeling like something is in your eye
  • Sensitivity to light
  • Eye infection

Dexamethasone serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Severe allergic reaction: hives; trouble breathing; swelling in the face, tongue, or throat

Source: DailyMed

The following Dexamethasone side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Aggression

agitation

anxiety

blurred vision

decrease in the amount of urine

dizziness

fast, slow, pounding, or irregular heartbeat or pulse

headache

irritability

mental depression

mood changes

nervousness

noisy, rattling breathing

numbness or tingling in the arms or legs

pounding in the ears

swelling of the fingers, hands, feet, or lower legs

trouble thinking, speaking, or walking

troubled breathing at rest

weight gain

Incidence not known

Abdominal or stomach cramping and/or burning (severe) or pain

backache

bloody, black, or tarry stools

cough or hoarseness

darkening of the skin

decrease in height

decreased vision

diarrhea

dry mouth

eye pain

eye tearing

facial hair growth in females

fainting

fatigue

fever or chills

flushed, dry skin

fractures

fruit-like breath odor

full or round face, neck, or trunk

heartburn and/or indigestion (severe and continuous)

increased hunger

increased thirst

increased urination

loss of appetite

loss of sexual desire or ability

lower back or side pain

menstrual irregularities

muscle pain or tenderness

muscle wasting or weakness

nausea

pain in the back, ribs, arms, or legs

painful or difficult urination

skin rash

sleeplessness

sweating

trouble healing

trouble sleeping

unexplained weight loss

unusual tiredness or weakness

vision changes

vomiting

vomiting of material that looks like coffee grounds

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Increased appetite

Incidence not known

Abnormal fat deposits on the face, neck, and trunk

acne

dry scalp

lightening of normal skin color

red face

reddish purple lines on the arms, face, legs, trunk, or groin

swelling of the stomach area

thinning of the scalp hair

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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