Skip to main content
Lialda

Lialda Side Effects

Robert Chad Hakim, PharmD, BCCCPAllison Gourley, PharmD
Reviewed by Robert Chad Hakim, PharmD, BCCCP, Allison Gourley, PharmD
Last reviewed on August 15, 2024

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

Less Common Side Effects

  • Stomach bloating
  • Indigestion
  • Back pain
  • Joint pain
  • Fatigue
  • High blood pressure
  • Rash
  • Itching
  • Hair loss

Note: Side effects listed were reported by adults who took 2.4 grams of mesalamine DR (Lialda) per day for maintenance of remission. Side effects might differ depending on dosage and age.

Lialda serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Kidney damage: urinating less often than usual; dry and itchy skin; muscle cramps; swelling in your feet, ankles, or hands
  • Kidney stone: trouble urinating, bloody urine, fever, chills, back or side pain
  • Liver problems: stomach bloating, right-sided stomach pain, yellowing of your skin or the whites of your eyes, dark urine
  • Serious allergic reactions: hives, swelling of the lips or tongue, trouble breathing
  • Serious skin reactions: hives, blisters, peeling skin, skin reddening, fever, sore throat, swollen lymph nodes

Source: DailyMed

The following Lialda side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Bloody diarrhea

rectal bleeding

stomach pain

Less common

Bloody stools

bloody urine

blurred vision

chest tightness

chills

clay-colored stools

cough

dark urine

diarrhea

difficulty with breathing

dizziness

fever

full or bloated feeling

general feeling of discomfort or illness

headache

itching, skin rash

joint pain

loss of appetite

muscle aches and pains

nausea

nervousness

pain or tenderness around the eyes and cheekbones

pounding in the ears

pressure in the stomach

runny or stuffy nose

shivering

slow or fast heartbeat

sore throat

stomach cramps

sweating

swelling of the stomach area

trouble sleeping

unpleasant breath odor

unusual tiredness or weakness

vomiting

vomiting of blood

yellow eyes or skin

Rare

Anxiety

back pain

blue or pale skin

chest pain, possibly moving to the left arm, neck, or shoulder

Incidence not known

Black, tarry stools

blistering, peeling, or loosening of the skin

bloating

change in the ability to see colors, especially blue or yellow

chest discomfort

constipation

decreased frequency or amount of urine

dry cough

greatly increased frequency of urination or amount of urine

hives or welts

hoarseness

inability to move the arms and legs

increased thirst

indigestion

large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals

light-colored stools

lower back or side pain

muscle weakness, sudden and progressing

pain in the ankles or knees

painful or difficult urination

painful, red lumps under the skin, mostly on the legs

rapid breathing

red skin lesions, often with a purple center

red, irritated eyes

severe nausea or vomiting

sores, ulcers, or white spots in the mouth or on the lips

stomach tenderness

sudden numbness and weakness in the arms and legs

swelling of the feet or lower legs

swollen or painful glands

thickening of bronchial secretions

unusual bleeding or bruising

weight gain

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Sneezing

Less common

Acne

belching

continuing ringing or buzzing or other unexplained noise in the ears

difficulty with moving

dizziness or lightheadedness

excess air or gas in the stomach or bowels

feeling of constant movement of self or surroundings

hair loss or thinning of the hair

hearing loss

heartburn

muscle stiffness

passing gas

sensation of spinning

stomach discomfort or upset

Incidence not known

Burning, numbness, tingling, or painful sensations

unsteadiness or awkwardness

weakness in the arms, hands, legs, or feet

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Was this page helpful?