Key takeaways:
The cost of levothyroxine (Levoxyl, Synthroid, Tirosint) may depend on the pharmacy you choose and whether you have insurance coverage, among other factors.
The average retail price for 30 levothyroxine 50 mcg tablets is $10.82 without insurance or discounts. But you could pay as little as $4.00 for the same prescription with a free GoodRx discount — or get it for free at certain pharmacies with GoodRx Companion.
Manufacturer savings programs and patient assistance programs can help lower the cost of brand-name versions of levothyroxine. But you shouldn’t change your thyroid medication without your prescriber’s OK.
Save on related medications
Levothyroxine (Levoxyl, Synthroid, Tirosint) is a medication that’s commonly prescribed for hypothyroidism (an underactive thyroid). Knowing how much levothyroxine costs is important, since you’ll likely take it long term and want to plan for ongoing medication expenses.
How much you pay for levothyroxine may depend on your dose, pharmacy, and whether you take generic levothyroxine or a brand-name version. Here’s what to know about how much levothyroxine costs without insurance and options that may help you save on your prescription.
How much does levothyroxine cost?
Levothyroxine is considered a fairly affordable medication. Without insurance or discounts, 30 tablets of 50 mcg generic levothyroxine cost $10.82 on average. The chart below shows average cash prices for common levothyroxine doses.
Levothyroxine dose and quantity | Average cash price |
|---|---|
25 mcg, 30 tablets | |
50 mcg, 30 tablets | |
75 mcg, 30 tablets | |
88 mcg, 30 tablets | |
100 mcg, 30 tablets | |
112 mcg, 30 tablets | |
125 mcg, 30 tablets | |
137 mcg, 30 tablets | |
150 mcg, 30 tablets | |
175 mcg, 30 tablets | |
200 mcg, 30 tablets | |
300 mcg, 30 tablets |
Factors that affect the cost of levothyroxine
Factors that can affect the cost of levothyroxine include:
Brand-name vs. generic availability: Generic levothyroxine is typically more affordable than its brand-name counterparts. But keep in mind that switching between versions isn’t recommended without your prescriber’s OK.
Dose and quantity: The cash price of levothyroxine can differ based on the dose. The quantity of tablets you’re prescribed can also affect how much you pay.
Location: Prices for prescription medications vary across different areas of the country. For example, according to GoodRx research, people in Little Rock, Arkansas, tend to pay more for prescription medications than people in Houston.
Pharmacy: Pharmacies negotiate their own pricing for prescription medications. So the cash price of levothyroxine can vary among different pharmacies, even ones located in the same neighborhood. GoodRx can help you compare prices at pharmacies in your area to help you find the lowest price.
Insurance coverage: If you have prescription insurance, it may lower what you pay for levothyroxine. But you may still have out-of-pocket costs, such as a deductible, copays, or coinsurance. You can check your coverage details in your plan’s summary of benefits and coverage online or by calling the number on the back of your prescription insurance card.
Does insurance cover levothyroxine?
Nearly all prescription insurance plans cover levothyroxine. About 99% of commercial plans and Medicare plans — and 100% of Affordable Care Act (ACA) plans — cover the generic medication. Medicaid also covers levothyroxine for 99.9% of enrollees. But about 5% of Medicaid enrollees have to get prior authorization for coverage. If you have to get prior authorization, your prescriber will need to provide your insurance company with additional information before you can get coverage.
How different insurance plans cover levothyroxine
The table below shows the likelihood of having coverage for levothyroxine — as well as prior authorization and step therapy requirements — with different types of insurance plans.
Insurance type | Enrollees covered for levothyroxine 50 mcg tablets | Enrollees required to get prior authorization | Enrollees required to do step therapy |
|---|---|---|---|
100% | 0% | 1.7% | |
Commercial plans (excluding ACA plans) | 99.1% | 0% | 0.4% |
Medicare, including original Medicare and Medicare Advantage plans | 99.7% | 0% | 0% |
Medicaid, including state-run and managed care plans | 99.9% | 5.1% | 0% |
Source: Managed Markets Insight & Technology, LLC™, as of June 13, 2025. (See methodology below.)
What to do if levothyroxine isn’t covered by your insurance?
If your insurance doesn’t cover levothyroxine, consider these options:
Ask your prescriber to submit a letter of medical necessity or request a formulary exception on your behalf. If the request is denied, you can appeal the decision.
Talk to your prescriber about levothyroxine alternatives. They can see if a different thyroid hormone medication may be less costly or more likely to be covered by your insurance.
Look into other savings options, such as GoodRx discounts.
Ways to save on levothyroxine
Whether or not you have insurance coverage, there are ways to save on the cost of levothyroxine. Here are six options to consider.
1. Use a GoodRx coupon
A free GoodRx discount could help lower the cost of levothyroxine. The table below shows how low GoodRx prices compare with average cash prices for common levothyroxine doses.
Levothyroxine dose and quantity | Average cash price | GoodRx low price |
|---|---|---|
25 mcg, 30 tablets | ||
50 mcg, 30 tablets | ||
75 mcg, 30 tablets | ||
88 mcg, 30 tablets | ||
100 mcg, 30 tablets | ||
112 mcg, 30 tablets | ||
125 mcg, 30 tablets | ||
137 mcg, 30 tablets | ||
150 mcg, 30 tablets | ||
175 mcg, 30 tablets | ||
200 mcg, 30 tablets | ||
300 mcg, 30 tablets |
To save with a GoodRx coupon:
Visit www.goodrx.com or download the GoodRx app.
Search for “levothyroxine,” and then click or tap “Find the lowest prices.”
Select your prescribed dose and quantity.
Choose if you want to receive the discount information by text or email. You can also take a screenshot on your phone or save it to your phone’s digital wallet.
To avoid delays, give the discount information to your pharmacy before you pick up your prescription.
Keep in mind: GoodRx savings may vary by pharmacy and geographic location. The GoodRx website and app can help you compare prices in your area.
2. Enroll in GoodRx Companion
You can access discounted prescription medications with a GoodRx Companion subscription. Over 250 medications (including some doses of levothyroxine) are available for free at certain pharmacies. And hundreds more are available for under $10 per month.
The GoodRx Companion program also includes benefits to help you cut your self-pay costs, such as lower prices for online care visits, discounts on dental care, and other health service savings.
3. See if you qualify for manufacturer savings programs
You may be able to save money on a brand-name form of levothyroxine with a savings card or prescription delivery program from the manufacturer:
Synthroid: You may be able to pay $29.50 for a 30-day supply, $54 for a 60-day supply, or $75 for a 90-day supply through the Synthroid Delivers Program. This is a cash-pay program, meaning insurance isn’t required or accepted. If you qualify, your medication will be delivered to you directly from the manufacturer. Or you may be able to use a copay savings card to pay as little as $25 per month with insurance, or $39.95 per month without insurance, at the pharmacy of your choosing.
Unithroid: You may be able to pay as little as $3 per month for Unithroid if you have commercial insurance. You aren’t eligible for this savings program if you have government-funded insurance, such as Medicare or Medicaid. But there are no insurance requirements for the Unithroid At Your Door program. Through this program, you could get Unithroid delivered directly to you for a cash price of $28 for a 30-day supply or $72 for a 90-day supply
Tirosint or Tirosint-SOL: You may be able to pay as little as $25 for a 30-day supply, or $60 for a 90-day supply, if you have commercial insurance. Savings are also available for those without insurance, with prices as low as $50 per month.
Thyquidity: You may be able to pay as little as $0 for your prescription if you have commercial insurance. (People with government-funded insurance are not eligible.) Or you could get Thyquidity shipped directly to you for $99 per bottle if you don’t have insurance coverage.
Each program has certain eligibility requirements you must meet to access savings. Keep in mind that you shouldn’t switch from generic levothyroxine to a brand-name version without your prescriber’s OK. If your prescriber approves a switch, you’ll need a new prescription for the brand-name product to access manufacturer savings.
4. See if you qualify for a patient assistance program
Brand-name Synthroid is available at no cost through the myAbbVie Assist program. This program is available to people who are uninsured or underinsured and meet eligibility and income requirements. You can apply online or by calling 1-800-222-6885.
5. Ask about a 90-day supply
Some pharmacies may cut you a deal on the cash price of levothyroxine if you buy more than 1 month of medication at a time. Some insurance plans also offer savings for filling a 90-day supply, but you may need to use a specific mail-order pharmacy to access the savings. You may also need a new prescription to fill more than 1 month of medication at a time in some cases. Ask your pharmacist for more information.
6. Tap into your HSA, FSA, or HRA
If you have a health savings account (HSA), flexible spending account (FSA), or health reimbursement arrangement (HRA), you can use it to help cover your out-of-pocket costs for levothyroxine. These tax-advantaged healthcare accounts let you pay for eligible expenses with tax-free dollars.
Pay directly with your HSA or FSA card at the pharmacy, or cover the cost yourself and request reimbursement. The funds in HSAs and some HRAs roll over annually. But you typically have to use FSA dollars before a certain deadline or they’ll expire.
Frequently asked questions
Most likely, you’ll need to take levothyroxine long term. That’s because hypothyroidism doesn’t typically go away on its own, and there isn’t currently a cure for it. That being said, your prescriber will monitor your thyroid hormone levels over time to ensure they stay within the goal range. They can adjust your levothyroxine dose or stop treatment if your lab work justifies a change. But you shouldn’t stop taking levothyroxine on your own. Untreated low thyroid levels can lead to serious complications, such as heart problems and nerve damage.
Yes, as long as your thyroid hormone levels stay within the goal range, it’s safe — and usually necessary — to take levothyroxine long term. Just be sure to stay on top of your regular lab appointments and let your prescriber know if you experience any symptoms of low or high thyroid levels during treatment.
Most likely, you’ll need to take levothyroxine long term. That’s because hypothyroidism doesn’t typically go away on its own, and there isn’t currently a cure for it. That being said, your prescriber will monitor your thyroid hormone levels over time to ensure they stay within the goal range. They can adjust your levothyroxine dose or stop treatment if your lab work justifies a change. But you shouldn’t stop taking levothyroxine on your own. Untreated low thyroid levels can lead to serious complications, such as heart problems and nerve damage.
Yes, as long as your thyroid hormone levels stay within the goal range, it’s safe — and usually necessary — to take levothyroxine long term. Just be sure to stay on top of your regular lab appointments and let your prescriber know if you experience any symptoms of low or high thyroid levels during treatment.
The bottom line
The cost of levothyroxine may depend on the pharmacy you choose and whether you have insurance coverage, among other factors.The average retail price for 30 levothyroxine 50 mcg tablets is $10.82 without insurance or discounts. But you could pay as little as $4.00 for the same prescription with a free GoodRx discount. Or you could get it for free at certain pharmacies with GoodRx Companion.
Manufacturer savings programs and patient assistance programs can help lower the cost of brand-name versions of levothyroxine. But you shouldn’t switch your thyroid medication without your prescriber’s OK.
Why trust our experts?
Methodology
We obtained national prescription coverage data for each medication from Managed Markets Insight & Technology (MMIT). The data reflects health insurance coverage as of June 2025.
We calculated the percentage of enrollees in plans that cover each medication by dividing the number of enrollees covered for the medication within a specific insurance channel (e.g., ACA, Medicare, Medicaid) by the total number of enrollees in all plans within that channel.
We determined the percentage of enrollees in plans with a prior authorization requirement by calculating the proportion of enrollees in plans that required prior authorization for the medication within each channel.
Finally, we measured the percentage of enrollees in plans with a step therapy requirement by calculating the proportion of enrollees in plans that imposed step therapy requirements for the medication in each channel.
These estimates, derived from national MMIT coverage data, provide insight into health insurance coverage for each medication. They take into account restrictions such as prior authorization, step therapy, and quantity limits. The percentages are expressed relative to the total number of enrollees covered by various insurance channels, including ACA plans, commercial (excluding ACA) plans, Medicare, and Medicaid (both state-run and managed care plans).
References
AbbVie. (n.d.). Patient assistance.
Medicaid.gov. (n.d.). Managed care.
Synthroid. (n.d.). Support programs. AbbVie.
Synthroid. (n.d.). Synthroid Delivers Program.
Thyquidity. (n.d.). Olivia2You. Olivia Therepeutics.
Tirosint. (n.d.). Savings and support. IBSA Pharma.
Unithroid. (n.d.). Save on Unithroid. Amneal Pharmaceuticals.
