Typical dosage for Lupron Depot
Lupron Depot is available in two strengths: 3.75 mg and 11.25 mg. Depending on the dose, the medication can be injected once every month or once every 3 months.
Endometriosis:
The typical dose is 3.75 mg injected into the muscle (intramuscularly or IM) once a month for up to 6 months. Alternatively, the 11.25 mg dose is injected IM every 3 months for up to 2 doses.
Lupron Depot can be given by itself. The medication can also be used together with 5 mg of norethindrone acetate (Aygestin) that's taken by mouth every day. If needed, your provider might repeat treatment for a maximum of 1 year.
Uterine fibroids:
The typical dose is 3.75 mg injected IM once a month for up to 3 months. Alternatively, the 11.25 mg dose is injected IM for only one time. Lupron Depot is typically used together with iron supplementation.
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