Latuda (Lurasidone) Dosages: Your GoodRx Guide

Latuda (lurasidone) is a prescription medication that treats schizophrenia and bipolar depression (depression due to bipolar disorder). It’s an atypical antipsychotic medication that affects dopamine and serotonin levels in the brain.

If you or someone you know has been prescribed Latuda, it’s important to know how to take it safely. In this guide, we’ll review the recommended Latuda dosages for adults and children. Remember to check with your prescriber or pharmacist if you have questions about your Latuda dosage. It could be different from what’s covered here.

What’s the typical Latuda dosage for adults?

Latuda is approved to treat schizophrenia and bipolar depression in adults. Mental health conditions vary from person to person. So your prescriber will determine your Latuda dosage based on how you respond to the medication. The recommended dosage range is based on what you’re taking it for.

Schizophrenia

The typical starting Latuda dosage for adults with schizophrenia is 40 mg by mouth once daily with food. Your prescriber will assess your response and slowly raise your dosage as needed. Latuda’s maximum recommended dosage for schizophrenia is 160 mg daily.

Depressive episodes associated with bipolar 1 disorder

Adults experiencing bipolar depression typically start with 20 mg of Latuda by mouth once daily with food. You may take Latuda alone or along with another medication, such as lithium (Lithobid).

Your prescriber will adjust your Latuda dosage as needed based on your symptoms. The maximum recommended Latuda dosage for bipolar depression is 120 mg daily. But 20 mg to 60 mg daily works well for most adults.

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What’s the typical Latuda dosage for children and adolescents?

Latuda is approved to treat schizophrenia in adolescents ages 13 to 17, and bipolar depression in children and adolescents ages 10 to 17. The Latuda dosage for your child is based on why they’re taking it and their response to the medication.

Schizophrenia

The typical starting Latuda dosage for schizophrenia in adolescents is 40 mg once daily with food. Your child’s prescriber may then raise the dose up to a maximum of 80 mg daily as needed.

Depressive episodes associated with bipolar 1 disorder

For children ages 10 to 17 with bipolar depression, the typical starting dosage of Latuda is 20 mg by mouth once daily with food. After 1 week, your child’s prescriber may increase their dose as needed.

The highest recommended Latuda dosage for bipolar depression in children and adolescents is 80 mg per day. But 20 mg to 40 mg daily works well for most in this age group.

How to take Latuda

Latuda comes as an oral tablet in the following doses:

• 20 mg

• 40 mg

• 60 mg

• 80 mg

• 120 mg

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You should take Latuda with food — a meal or snack containing at least 350 calories is best. Food helps your body absorb Latuda so it can reach its full effect. But you should avoid grapefruit juice while you’re taking Latuda. It can raise the amount of Latuda in the body to unsafe levels.

Are there any dosage adjustments for medical conditions?

Sometimes, your Latuda dosage may need to be adjusted because of other health conditions or interactions. Keep in mind, the Latuda dosage will vary from person to person. Your prescriber will help decide if the dosage changes below apply to you.

Dosage for people with kidney problems

Lower Latuda dosages are recommended for people with kidney problems, such as chronic kidney disease. If you have moderate to severe kidney problems, it’s best to start with a lower Latuda dosage of 20 mg daily. And doses over 80 mg daily aren’t recommended.

Dosage for people with liver problems

A lower Latuda dosage is also recommended if you have moderate or severe liver disease. A lower starting dosage of 20 mg daily is best. Your dosage may be raised to a maximum of 80 mg per day if you have moderate liver issues. But if you have severe liver problems, Latuda dosages over 40 mg daily aren’t recommended.

Dosage with certain interactions

Certain medications interact with Latuda and can raise the levels of Latuda in your body. If you’re taking one of these medications, your prescriber will likely start Latuda at half the usual dose. If you’re already taking Latuda and you start taking one of these medications, your Latuda dosage should be cut in half. The medications include:

• Calcium channel blockers, such as diltiazem (Cardizem) and verapamil (Verelan)

• Erythromycin (Ery-tab, E.E.S.)

• Fluconazole (Diflucan)

• Atazanavir (Reyataz)

Make sure to give your prescriber a complete list of medications and supplements you take before starting Latuda. And check with them before starting any new medications while you’re taking it. They can make any necessary changes to your Latuda dosage based on these interactions.

What happens if you miss a dose of Latuda?

If you miss a dose of Latuda, take it with food as soon as possible. But skip the missed dose if it’s almost time for your next one. You shouldn’t take two doses at once to make up for a missed dose.

If you miss more than one dose of Latuda, contact your pharmacist or prescriber. They can help you get back on track with your medication safely. Consider tools, such as a medication reminder app or daily pill organizer, to help you remember your medication.

What should you do if you take too much Latuda?

If you accidentally take an extra dose of Latuda, it’s unlikely to cause you any serious harm. But you may have a higher risk of side effects, such as nausea or drowsiness.

Large doses of Latuda may cause more serious effects, such as an irregular heartbeat, vomiting, and high or low blood pressure. Severe uncontrolled body movements can also happen.

If you or someone you know has taken too much Latuda, contact your healthcare team or call the Poison Control Center at 1-800-222-1222. But if you have chest pain or you’re having trouble breathing, it’s best to seek emergency medical care.

How to save on Latuda

There are ways to save on Latuda, which is available as both a brand-name and generic medication. GoodRx can help you save over 95% off the average retail price of the generic version. Generic Latuda’s price at certain pharmacies is less than $22.00 with a free GoodRx discount.

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Written by:

Justin DeFlorian, PharmD, BCPS

Justin DeFlorian, PharmD, BCPS, is a board-certified clinical pharmacist. He received his Doctor of Pharmacy degree from the University of Wisconsin-Madison.

Edited by:

Stacia Woodcock, PharmD

Stacia Woodcock, PharmD, is a pharmacy editor for GoodRx. She earned her Doctor of Pharmacy degree from the University of Kentucky and is licensed in New York and Massachusetts.

Reviewed by:

Christina Aungst, PharmD

Christina Aungst, PharmD, is a pharmacy editor for GoodRx. She began writing for GoodRx Health in 2019, transitioning from freelance writer to editor in 2021.

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