provider image
Welcome! You’re in GoodRx for healthcare professionals. Now, you’ll enjoy a streamlined experience created specifically for healthcare professionals.
Skip to main content

Juvisync

sitagliptan and simvastatin
Used for Diabetes Type 2, High Cholesterol
Used for Diabetes Type 2, High Cholesterol

Juvisync (sitagliptin / simvastatin) is a combination medication used for people with Type 2 diabetes who might also have high cholesterol. It's used along with diet and exercise to help lower blood sugar and "bad" cholesterol, which can help lower the risk of heart attack and stroke. This medication has been discontinued by the manufacturer and is no longer available in the United States.

Reviewed by:
reviewer
Ally Tsai, PharmD
reviewer
Cydnee Ng, PharmD
Last reviewed on May 24, 2022
BasicsFAQsInteractionsAlternativesPricesMedicare
basics-icon

What is Juvisync (sitagliptin / simvastatin)?

What is Juvisync (sitagliptin / simvastatin) used for?

Type 2 diabetes with:

  • High cholesterol

  • Risk of heart attack or stroke

How Juvisync (sitagliptin / simvastatin) works

Are you looking for information on Januvia (sitagliptin) or simvastatin (Zocor) instead?

Drug Facts

Common BrandsJuvisync (brand no longer available)
Drug ClassDPP-4 inhibitor / Statin
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityDiscontinued
faqs

Frequently asked questions about Juvisync (sitagliptin / simvastatin)

What is Juvisync (sitagliptin / simvastatin)?
Juvisync (sitagliptin / simvastatin) is a combination of two medications. Sitagliptin is a medication that helps bring down blood sugar in people with Type 2 diabetes. It works by blocking dipeptidyl peptidase-4 (DPP-4), which is a protein that lowers the amount of insulin in the body. By stopping DPP-4, sitagliptin helps the body make more insulin so it can break down sugar for energy. This lowers blood sugar levels. Simvastatin is a statin that works by slowing the production of cholesterol in the body. It helps lower your low-density lipoprotein (LDL, or "bad" cholesterol) and triglyceride (fat) levels. This can help lower the risk of heart attack or stroke. Statins are often recommended in people with Type 2 diabetes, because they also tend to have high cholesterol levels. Both diabetes and high cholesterol can raise your risk of heart attack or stroke.
Is Juvisync (sitagliptin / simvastatin) still available?
No, Juvisync (sitagliptin / simvastatin) has been discontinued as of 2013 and is no longer available in the United States.
Why was Juvisync (sitagliptin / simvastatin) discontinued?
The manufacturer (Merck) voluntarily discontinued Juvisync (sitagliptin / simvastatin) in 2013 for business reasons only. It wasn't taken off the market for safety concerns or lack of benefit.
What alternatives can I use instead of Juvisync (sitagliptin / simvastatin)?
Juvisync (sitagliptin / simvastatin) is a combination of two medications, sitagliptin and simvastatin, which are both still available and are sold separately. Sitagliptin is only available as brand-name Januvia. Simvastatin is available as both brand-name Zocor and generic. Keep in mind that there are many factors that your provider must consider when choosing a medication for Type 2 diabetes. Talk with your provider to determine which medications are best for your health conditions.
GoodRxEducationalIcon

How to save using GoodRx

Compare Prices
1. Compare PricesSpecify your dosage and quantity to find out exactly how much you can save.
Select your free coupon
2. Select your free couponYou can use the displayed coupon, or compare prices at other pharmacies near you.
Show coupon to your pharmacist
3. Show coupon to your pharmacistPresent your printed or electronic coupon when you pick up your prescription.
Get free couponLearn more
interactions

Interactions between Juvisync (sitagliptin / simvastatin) and other drugs

Juvisync (sitagliptin / simvastatin) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Juvisync (sitagliptin / simvastatin). Please note that only the generic name of each medication is listed below.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

alternatives

What are alternatives to Juvisync (sitagliptin / simvastatin)?

There are a number of medications that your doctor can prescribe in place of Juvisync (sitagliptin / simvastatin). Compare a few possible alternatives below.
Juvisync (sitagliptin / simvastatin)
Used for:

Type 2 diabetes with:

  • High cholesterol

  • Risk of heart attack or stroke

View Prices
Januvia (sitagliptin)
Used for:

  • Type 2 diabetes in adults

$335.50 Lowest GoodRx priceView Prices
Simvastatin (Zocor)
Used for:
$12.60 Lowest GoodRx priceView Prices

Get savings updates for Juvisync (sitagliptin / simvastatin)

Receive price alerts, news, and other messages from GoodRx about Juvisync (sitagliptin / simvastatin) and other healthcare topics and relevant savings offers.

By signing up, I agree to GoodRx's Terms and Privacy Policy, and to receive marketing messages from GoodRx.

Browse medications

View All

Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.