Iyuzeh (latanoprost) is an eye drop medication. It helps lower pressure in the eye for certain people with glaucoma or high eye pressure. Typically, this medication works best when it's used once a day at night. Common side effects of Iyuzeh (latanoprost) include eye redness, eye irritation, and itchy eyes. Iyuzeh (latanoprost) is the first and only preservative-free formulation of latanoprost.
Iyuzeh (latanoprost) is a prostaglandin eye drop medication. It works similarly to the prostaglandin chemical your body naturally makes. When placed into the eyes, Iyuzeh (latanoprost) helps drain the fluid inside your eyes. This helps your eye pressure go down.
The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Contact your healthcare provider immediately if you experience any of the following.
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
More common
Eye pain or stinging
Less common
Decreased vision
painful irritation of the clear front part of the eye
swelling or redness of the eye and the lining of the eyelid
Incidence not known
Arm, back, or jaw pain
blistering, peeling, or loosening of the skin
blurred vision or other change in vision
burning, dry, or itching eyes
chest pain or discomfort
chest tightness or heaviness
chills
difficulty breathing
discharge, excessive tearing
fast, irregular, pounding, or racing heartbeat or pulse
joint or muscle pain
noisy breathing
red skin lesions, often with a purple center
sensitivity of the eye to light
sores, ulcers, or white spots in the mouth or on the lips
tearing
unusual tiredness or weakness
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Drainage from the eyes
longer and thicker eyelashes
Less common
Eyelash discoloration
feeling of having something in the eye
Incidence not known
Darkening of the eyelid skin color
dizziness
headache
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
It typically takes about 3 to 4 hours for Iyuzeh (latanoprost) to start lowering eye pressure after you use the medication. Iyuzeh (latanoprost) works best when it's used consistently in the affected eye(s) once daily in the evening. Missing a dose or using this medication more than once a day can cause Iyuzeh (latanoprost) to not work as well. Your provider will check your eye pressure during routine eye exams to make sure Iyuzeh (latanoprost) is working properly for you.
Yes, you can use Iyuzeh (latanoprost) with certain other eye drops. In fact, if you have glaucoma, your provider might add on a different eye drop medication to help lower your eye pressure. But you shouldn't use Iyuzeh (latanoprost) together with other similar eye drop medications, such as Lumigan (bimatoprost) and travoprost (Travatan Z). Using more than one prostaglandin eye drop medication can cause them to work less well. As a result, your eye pressure can actually go up and your glaucoma can worsen. If you're using more than one eye drop medication, make sure to wait at least 5 minutes between each medication so the next eye drop doesn't rinse off the previous one.
Preservative ingredients in eye drop medications can sometimes cause serious eye irritation, especially if you use them for a long time. Iyuzeh (latanoprost) doesn't contain any preservatives so it might be less likely to cause eye discomfort. In clinical studies, people who used preservative-free Iyuzeh (latanoprost) had less eye redness and irritation than those who used latanoprost (Xalatan) that contains preservatives. Speak to your provider if preservative-free Iyuzeh (latanoprost) best fits your needs.
Iyuzeh and Xalatan are both eye drop medications that contain latanoprost. Both medications are used to treat high eye pressure in certain people with glaucoma. While latanoprost (Xalatan) contains preservatives and comes in a bottle that can be used multiple times before it's thrown away, Iyuzeh (latanoprost) is preservative-free and comes in vials that can each only be used once. Additionally, in two clinical studies comparing these medications, Iyuzeh (latanoprost) was less likely to cause eye redness and eye discomfort than latanoprost (Xalatan). Iyuzeh (latanoprost) and latanoprost (Xalatan) are available by prescription from your provider, but only latanoprost (Xalatan) has lower-cost generics available.
According to the manufacturer’s instructions, Iyuzeh (latanoprost) should be used at night every day. This might be because some research suggests that your eye pressure might be higher at night. On the other hand, other research about a similar glaucoma eye drop suggests that there might not be a big difference between how well the medication works if you use it at night or in the morning. It might be more important to make sure you use it consistently every day. Talk with your provider about when the best time to use Iyuzeh (latanoprost) is for you.
One side effect of Iyuzeh (latanoprost) is that it can make you grow more eyelashes or cause the eyelashes you already have to become longer and thicker. These eyelash changes usually go away after you stop using this medication. Keep in mind that Iyuzeh (latanoprost) isn't FDA approved to help your eyelashes grow. But there's a different prostaglandin eye drop called bimatoprost (Latisse) that's FDA approved for this specific purpose.
Iyuzeh (latanoprost) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Iyuzeh (latanoprost) can sometimes darken the color of your eyes, eyelids, and eyelashes. Most people notice these changes after they've used Iyuzeh (latanoprost) for a few months or years. Color changes in the eyes might become permanent, while color changes to the eyelids and eyelashes might not. Please be aware that these side effects aren't known to be harmful. But it's best to check in with your provider regularly so they can make sure your eyes stay healthy.
Iyuzeh (latanoprost) can make your eyelashes grow longer and thicker. These changes usually go away after you stop using Iyuzeh (latanoprost).
Iyuzeh (latanoprost) can cause or worsen inflammation of the eyes. Your risk of eye inflammation is higher if you currently have an eye infection or have had a viral eye infection in the past (herpes keratitis). Let your provider know if you have symptoms of red, itchy, or painful eyes. Ask them if you should continue to use Iyuzeh (latanoprost) while your eyes are inflamed.
Sometimes, people using Iyuzeh (latanoprost) have developed swelling in the part of the eye called the retina This condition is known as macular edema. In general, the risk of macular edema is higher in people with certain medical conditions, such as diabetes, older age, and other eye problems. In addition, if you've had cataract surgery in the past, using Iyuzeh (latanoprost) might also raise your risk of macular edema. Let your provider know right away if you notice any blurry vision or vision changes while using this medication.
| Dosage | Quantity | Price as low as | Price per unit |
|---|---|---|---|
| 30 containers of 0.005% | 1 carton | $264.04 | $264.04 |
The typical dose is 1 drop in the affected eye(s) once daily in the evening.
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.