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Iyuzeh Coupon - Iyuzeh 30 containers of 0.005% carton

Iyuzeh

latanoprost
Used for Eye Pressure, Glaucoma

Iyuzeh (latanoprost) is an eye drop medication. It helps lower pressure in the eye for certain people with glaucoma or high eye pressure. Typically, this medication works best when it's used once a day at night. Common side effects of Iyuzeh (latanoprost) include eye redness, eye irritation, and itchy eyes. Iyuzeh (latanoprost) is the first and only preservative-free formulation of latanoprost.

Reviewed by:Last reviewed on April 26, 2023
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What is Iyuzeh (latanoprost)?

What is Iyuzeh (latanoprost) used for?

How Iyuzeh (latanoprost) works

Iyuzeh (latanoprost) is a prostaglandin eye drop medication. It works similarly to the prostaglandin chemical your body naturally makes. When placed into the eyes, Iyuzeh (latanoprost) helps drain the fluid inside your eyes. This helps your eye pressure go down.

Drug facts

Common BrandsIyuzeh
Drug ClassProstaglandin
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityPrescription only
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Side effects of Iyuzeh (latanoprost)

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Eye redness (34%)
  • Eye irritation (19%)
  • Itchy eye (15%)
  • Eye discomfort (14%)
  • Feeling like there's something in your eye (12%)

Less Common Side Effects

  • Blurry vision
  • Watery eyes
  • Light sensitivity
  • Thicker or longer eyelashes
  • Darker eyes, eyelids, or eyelashes

Iyuzeh (latanoprost) serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Eye inflammation or infection
  • Macular edema: blurry vision, dull color vision

Source: FDA

The following Iyuzeh (latanoprost) side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Eye pain or stinging

Less common

Decreased vision

painful irritation of the clear front part of the eye

swelling or redness of the eye and the lining of the eyelid

Incidence not known

Arm, back, or jaw pain

blistering, peeling, or loosening of the skin

blurred vision or other change in vision

burning, dry, or itching eyes

chest pain or discomfort

chest tightness or heaviness

chills

cough

diarrhea

difficulty breathing

discharge, excessive tearing

fast, irregular, pounding, or racing heartbeat or pulse

itching

joint or muscle pain

noisy breathing

red skin lesions, often with a purple center

sensitivity of the eye to light

sore throat

sores, ulcers, or white spots in the mouth or on the lips

tearing

unusual tiredness or weakness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Drainage from the eyes

longer and thicker eyelashes

Less common

Eyelash discoloration

feeling of having something in the eye

Incidence not known

Darkening of the eyelid skin color

dizziness

headache

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Pros and cons of Iyuzeh (latanoprost)

Pros

Cons

  • Interacts with other medications in the same class (e.g., travoprost (Travatan Z))
  • Might permanently change the color of your eyes
  • Can worsen eye inflammation
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Pharmacist tips for Iyuzeh (latanoprost)

pharmacist
  • Try to use Iyuzeh (latanoprost) around the same time in the evening every day. If you accidentally forget to use the medication, skip the missed dose. Then, use Iyuzeh (latanoprost) the next evening.
  • If you wear contact lenses, make sure to take them out before using Iyuzeh (latanoprost). Then, wait at least 15 minutes after using the medication to put them back in.
  • To use Iyuzeh (latanoprost), pull down your lower eyelid with one hand and hold the bottle upside down with the other. Make sure the tip of the bottle is above your eye, but don't let the tip touch your eye. Squeeze 1 drop of medication into your eye. Then, close your eye, and press your finger on the corner of your eye closest to your nose for a minute. Doing this helps the medication stay in your eye and prevents it from leaking into your nose.
  • If you need to use another eye drop medication in the same eye, wait at least 5 minutes after using Iyuzeh (latanoprost) so the second eye drop doesn't rinse off the first one.
  • Write down the date you open the foil pouch on the outside of the pouch. Remember to throw away any unused Iyuzeh (latanoprost) vials inside the foil pouch 30 days after opening it.
  • Keep Iyuzeh (latanoprost) in the original foil pouch at room temperature.
  • Don't open the Iyuzeh (latanoprost) vial until you're ready to use the medication. After you've placed a drop in the affected eye(s), throw the vial away. Don't save any leftover medication. These single-use vials don't have any preservatives in them to prevent germs from growing in the medication. So, opening the vial before you're ready to use it and using any leftover medication can raise your risk of an eye infection.
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Common questions about Iyuzeh (latanoprost)

It typically takes about 3 to 4 hours for Iyuzeh (latanoprost) to start lowering eye pressure after you use the medication. Iyuzeh (latanoprost) works best when it's used consistently in the affected eye(s) once daily in the evening. Missing a dose or using this medication more than once a day can cause Iyuzeh (latanoprost) to not work as well. Your provider will check your eye pressure during routine eye exams to make sure Iyuzeh (latanoprost) is working properly for you.

Yes, you can use Iyuzeh (latanoprost) with certain other eye drops. In fact, if you have glaucoma, your provider might add on a different eye drop medication to help lower your eye pressure. But you shouldn't use Iyuzeh (latanoprost) together with other similar eye drop medications, such as Lumigan (bimatoprost) and travoprost (Travatan Z). Using more than one prostaglandin eye drop medication can cause them to work less well. As a result, your eye pressure can actually go up and your glaucoma can worsen. If you're using more than one eye drop medication, make sure to wait at least 5 minutes between each medication so the next eye drop doesn't rinse off the previous one.

Preservative ingredients in eye drop medications can sometimes cause serious eye irritation, especially if you use them for a long time. Iyuzeh (latanoprost) doesn't contain any preservatives so it might be less likely to cause eye discomfort. In clinical studies, people who used preservative-free Iyuzeh (latanoprost) had less eye redness and irritation than those who used latanoprost (Xalatan) that contains preservatives. Speak to your provider if preservative-free Iyuzeh (latanoprost) best fits your needs.

Iyuzeh and Xalatan are both eye drop medications that contain latanoprost. Both medications are used to treat high eye pressure in certain people with glaucoma. While latanoprost (Xalatan) contains preservatives and comes in a bottle that can be used multiple times before it's thrown away, Iyuzeh (latanoprost) is preservative-free and comes in vials that can each only be used once. Additionally, in two clinical studies comparing these medications, Iyuzeh (latanoprost) was less likely to cause eye redness and eye discomfort than latanoprost (Xalatan). Iyuzeh (latanoprost) and latanoprost (Xalatan) are available by prescription from your provider, but only latanoprost (Xalatan) has lower-cost generics available.

According to the manufacturer’s instructions, Iyuzeh (latanoprost) should be used at night every day. This might be because some research suggests that your eye pressure might be higher at night. On the other hand, other research about a similar glaucoma eye drop suggests that there might not be a big difference between how well the medication works if you use it at night or in the morning. It might be more important to make sure you use it consistently every day. Talk with your provider about when the best time to use Iyuzeh (latanoprost) is for you.

One side effect of Iyuzeh (latanoprost) is that it can make you grow more eyelashes or cause the eyelashes you already have to become longer and thicker. These eyelash changes usually go away after you stop using this medication. Keep in mind that Iyuzeh (latanoprost) isn't FDA approved to help your eyelashes grow. But there's a different prostaglandin eye drop called bimatoprost (Latisse) that's FDA approved for this specific purpose.

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Risks and warnings for Iyuzeh (latanoprost)

Iyuzeh (latanoprost) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

Darker eyes, eyelids, or eyelashes

  • Risk factors: Long-term use of Iyuzeh (latanoprost)

Iyuzeh (latanoprost) can sometimes darken the color of your eyes, eyelids, and eyelashes. Most people notice these changes after they've used Iyuzeh (latanoprost) for a few months or years. Color changes in the eyes might become permanent, while color changes to the eyelids and eyelashes might not. Please be aware that these side effects aren't known to be harmful. But it's best to check in with your provider regularly so they can make sure your eyes stay healthy.

Eyelash changes

Iyuzeh (latanoprost) can make your eyelashes grow longer and thicker. These changes usually go away after you stop using Iyuzeh (latanoprost).

Eye inflammation and infection

  • Risk factors: Eye inflammation | History of herpes eye infection | High risk for macular edema (e.g., diabetes, high blood pressure)

Iyuzeh (latanoprost) can cause or worsen inflammation of the eyes. Your risk of eye inflammation is higher if you currently have an eye infection or have had a viral eye infection in the past (herpes keratitis). Let your provider know if you have symptoms of red, itchy, or painful eyes. Ask them if you should continue to use Iyuzeh (latanoprost) while your eyes are inflamed.

Macular edema

  • Risk factors: High risk for macular edema (e.g., diabetes, high blood pressure)

Sometimes, people using Iyuzeh (latanoprost) have developed swelling in the part of the eye called the retina This condition is known as macular edema. In general, the risk of macular edema is higher in people with certain medical conditions, such as diabetes, older age, and other eye problems. In addition, if you've had cataract surgery in the past, using Iyuzeh (latanoprost) might also raise your risk of macular edema. Let your provider know right away if you notice any blurry vision or vision changes while using this medication.

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Iyuzeh (latanoprost) dosage

The average cost for 1 carton of 30 containers of 0.005% of Iyuzeh (latanoprost) is $264.04 with a free GoodRx coupon. This is 30.63% off the average retail price of $380.61.
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DosageQuantityPrice as low asPrice per unit
30 containers of 0.005%1 carton$264.04$264.04

Typical dosage for Iyuzeh (latanoprost)

The typical dose is 1 drop in the affected eye(s) once daily in the evening.

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Interactions between Iyuzeh (latanoprost) and other drugs

Iyuzeh (latanoprost) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Iyuzeh (latanoprost). Please note that only the generic name of each medication is listed below.

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

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What are alternatives to Iyuzeh (latanoprost)?

There are a number of medications that your doctor can prescribe in place of Iyuzeh (latanoprost). Compare a few possible alternatives below.
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References

Best studies we found

American Academy of Ophthalmology. (2016). Primary open-angle glaucoma.

Boyd, K. (2022). Eye pressure testing. American Academy of Ophthalmology.

Centers for Disease Control and Prevention. (2022). Basics of HSV (herpes simplex virus) keratitis.

GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.

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