The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Nerve problems that affect touch (up to 65%)
- Tender, red palms and sole of the feet (hand-foot syndrome) (up to 64%)
- Tiredness (up to 60%)
- Nausea (up to 53%)
- Bone, muscle and joint pain (up to 49%)
- Hair loss (up to 48%)
- Diarrhea (up to 44%)
- Low white blood cell count (up to 41%)
- Vomiting (up to 39%)
- Loss of appetite (up to 34%)
- Mouth sores (up to 31%)
- Stomach pain (up to 24%)
- Changes in nails (up to 24%)
- Constipation (up to 22%)
Please note: These side effects were reported by people who were treated with Ixempra (ixabepilone) alone or in combination with capecitabine (Xeloda).
Less Common Side Effects
- Skin rash
- Damage to the nerves that help with movement
- Changes in taste
- Darkening of skin
- Weight loss
- Headache
- Fever
Source: DailyMed
The following Ixempra side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur:
More common
Black, tarry stools
body aches or pain
burning, numbness, tingling, or painful sensations
burning pain on urination
chills
difficult or labored breathing
ear congestion
headache
loss of voice
lower back or side pain
painful or difficult urination
pale skin
red, swelling, or painful skin
scaling of the skin on the hands and feet
shortness of breath
sores, ulcers, or white spots on the lips, tongue, or inside the mouth
swelling of the hands, ankles, feet, or lower legs
swollen glands
tightness in the chest
tingling of the hands and feet
troubled breathing with exertion
ulceration of the skin
unsteadiness or awkwardness
unusual bleeding or bruising
unusual tiredness or weakness
unusual weight gain
weakness in the arms, hands, legs, or feet
Less common
Bleeding gums
blood in the urine or stools
confusion
decreased urination
dizziness
fainting
fast heartbeat
hoarseness
increase in heart rate
irritation
joint pain, stiffness, or swelling
lightheadedness
pinpoint red spots on the skin
rapid breathing
rash
sunken eyes
swelling of the eyelids, face, or lips
thirst
trouble with swallowing
wrinkled skin
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Bad, unusual, or unpleasant (after) taste
bone pain
change in taste
cracked lips
difficulty having a bowel movement (stool)
discoloration of the fingernails or toenails
feeling of warmth
hair loss or thinning of the hair
lack or loss of strength
loss of appetite
redness of the face, neck, arms, and occasionally, upper chest
stomach pain
sudden sweating
swelling or inflammation of the mouth
vomiting
Less common
Darkening of the skin
flaking and falling off of the skin
trouble with sleeping
unable to sleep
watering of the eyes
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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