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Indapamide Coupon - Indapamide 1.25mg tablet

indapamide

Generic Lozol
Used for Heart Failure, Hypertension
Used for Heart Failure, Hypertension

Indapamide is an oral tablet that's used to lower blood pressure and ease swelling (edema) caused by heart failure. Typically, the dose is once daily in the morning. Some common indapamide side effects of this medication include dizziness and feeling weak, which can put older adults at higher risk of falling. Indapamide is only available as a generic medication since the brand name (Lozol) has been discontinued.

Reviewed by:
reviewer
Ally Tsai, PharmD
reviewer
Daisy Chau, PharmD
Last reviewed on May 15, 2023
BasicsSide effectsPros & consPharmacist tipsFAQsWarningsDosageInteractionsCostContraindicationsAlternativesImagesReferencesPricesMedicare
basics-icon

What is Indapamide?

What is Indapamide used for?

  • High blood pressure

  • Swelling (edema) due to heart failure

How Indapamide works

Indapamide is a thiazide-like diuretic, also known as a water pill. It works in the kidneys to get rid of extra water and electrolytes (like sodium and potassium), which brings down swelling and lowers blood pressure. It also relaxes your blood vessels, which helps to lower your blood pressure more.

Drug Facts

Common BrandsLozol (brand no longer available)
Drug ClassThiazide-like diuretic (water pill)
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only
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What are the side effects of Indapamide?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

These side effects have been reported in up to 5% of people:
  • Headache
  • Body and back pain
  • Dizziness
  • Stuffy nose
  • Feeling weak or having low energy
  • Muscle cramps
  • Feeling nervous, anxious, or irritable

Other Side Effects

  • Drowsiness
  • Trouble sleeping
  • Feeling depressed
  • Blurry vision
  • Constipation
  • Diarrhea
  • Nausea
  • Vomiting
  • Belly pain
  • Chest pain
  • Indigestion
  • Cough
  • Throat pain
  • Pink eye
  • Weight loss
  • Irregular heart beat
  • Urinating more often
  • Tingling sensation
  • Dry mouth

Source: DailyMed

The following side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Agitation

anxiety

black, tarry stools

chest pain

cough or hoarseness

dark urine

dizziness

fever or chills

headache

irritability

light-colored stools

lower back or side pain

muscle cramps or spasms

painful or difficult urination

sneezing

sore throat

sores, ulcers, or white spots in the mouth or on the lips

stuffy or runny nose

swollen glands

unusual bleeding or bruising

unusual tiredness or weakness

yellow eyes and skin

Less common

Blurred vision

body aches or pain

burning, dry, or itching eyes

change in consciousness

cold sweats

confusion

decreased urine output

discharge, excessive tearing

discouragement

dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position

drowsiness

dry mouth

dryness or soreness of the throat

excessive muscle tone

fast, irregular, pounding, or racing heartbeat or pulse

feeling sad or empty

flushed, dry skin

frequent urination

fruit-like breath odor

increased hunger, thirst, and urination

increased urge to urinate during the night

increased volume of pale, dilute urine

joint pain, stiffness, or swelling

lack of appetite

loss of interest or pleasure

lower back, side, or stomach pain

mood changes

muscle pain, cramps, tension, stiffness, or tightness

nervousness

pain or tenderness around the eyes and cheekbones

redness, pain, swelling of the eye, eyelid, or inner lining of eyelid

sugar in the urine

sweating

swelling of the face, feet, lower legs, ankles, or hands

tender, swollen glands in the neck

tightness in the chest

trouble breathing

trouble concentrating

trouble in swallowing

trouble sleeping

voice changes

waking to urinate at night

Incidence not known

Change in near or distance vision

difficulty in focusing the eyes

eye pain

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Back pain

blistering, peeling, loosening of the skin

diarrhea

increased sensitivity of skin to sunlight

red irritated eyes

red skin lesions, often with a purple center

redness or other discoloration of the skin

severe sunburn

Less common

Acid or sour stomach

belching

bloating or swelling of the face, arms, hands, lower legs, or feet

constipation

decreased interest in sexual intercourse

heartburn

hives or rash

inability to have or keep an erection

indigestion

lack or loss of strength

loss in sexual ability, desire, drive, or performance

nausea

rapid weight gain

stomach discomfort or upset

tingling of the hands or feet

unusual weight gain or loss

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

pros-and-cons

Pros and cons of Indapamide

thumbs-up

Pros

Works well to control blood pressure compared to other medications in the same class

Is an option if you have both high blood pressure and heart failure

Only taken once a day by mouth

Available as a lower-cost generic medication

thumbs-down

Cons

Can cause low levels of important electrolytes, such as sodium and potassium

Requires routine blood tests to check electrolytes and kidney function

Might not be safe for people with severe kidney problems

Not recommended if for people with allergies to "sulfa" medications

pharmacist-tips

Pharmacist tips for Indapamide

pharmacist

  • Indapamide works to lower your blood pressure, but this can cause dizziness and lightheadedness. These are more likely to happen if you're suddenly standing up from a sitting or lying down position. Make sure to get up slowly from these positions after taking indapamide. Tell your provider if you experience fainting or dizziness while taking this medication.

    • Indapamide is a water pill that makes you urinate more often. Taking it in the morning will make it less likely for you to wake up in the middle of the night to use the bathroom.

      • If you're using indapamide to lower blood pressure and it's not enough on its own, your provider might prescribe additional blood pressure-lowering medications.

        • If you have diabetes, you might need to monitor your blood sugar levels more often when starting indapamide. This is because indapamide can raise your blood sugar levels and possibly worsen your diabetes. Let your provider know if there are changes to your blood sugar levels during treatment with this medication. Your provider might need to adjust the dose of your diabetic medications to help better control your blood sugar.

          • Sometimes, people with a "sulfa" allergy might also be allergic to indapamide. Let your provider or pharmacist know if you've had allergic reactions to any medications in the past.

            faqs

            Frequently asked questions about Indapamide

            Is indapamide a beta blocker?
            No, indapamide isn't a beta blocker. Instead it's a thiazide-like diuretic, also known as a water pill. Thiazide-like diuretics and beta blockers are both used to treat heart problems like heart failure and high blood pressure, but they work very differently. While indapamide works to get rid of extra fluid in your body, beta blockers slow down your heart rate to make it easier for your heart to pump blood around your body. Talk to your provider to see which medication is right for you.
            Can I take indapamide every other day?
            Indapamide is typically taken once daily. But for certain reasons, your provider might have you take it differently. So it's most important to take indapamide exactly as prescribed by your provider. If you've been taking this medication for a long time, don't suddenly stop or lower the dose of this medication without talking to your provider. Doing so might worsen your heart failure or cause your blood pressure to suddenly rise. This is more common in older adults who have been using indapamide for a long time.
            How long does it take indapamide to work to lower your blood pressure?
            Indapamide can take within 1 to 2 weeks of treatment to work. And if your blood pressure doesn't seem to improve after 4 weeks, talk to your provider. Your provider might need to raise your dose or add another medication.
            Does indapamide cause weight gain?
            No, indapamide isn't known to cause weight gain. In fact, indapamide might cause a little bit of weight loss since it gets rid of extra fluid from your body. Keep in mind that this medication helps you lose water weight, not body fat.
            Can indapamide cause low potassium?
            Yes, indapamide can cause low potassium. This is because water pills, such as indapamide, cause your kidneys to make more urine to get rid of extra water and electrolytes like sodium and potassium. During treatment with indapamide, you'll probably have regular lab appointments to make sure your potassium levels are normal. In addition, you might be asked to take a potassium supplement if your levels are too low. Talk to your provider right away if you have symptoms of muscle weakness, constipation, or tingling sensation.
            Does indapamide cause erectile dysfunction?
            Indapamide can make it difficult to get or maintain an erection. This is because certain medications that lower blood pressure (e.g., thiazide-like diuretics, beta blockers) slow down blood flow to the genital area. Talk to your provider if you're concerned about this side effect. Your provider might lower your dose or switch you to a different medication altogether.
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            What are the risks and warnings for Indapamide?

            Indapamide can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

            risk-warning

            Electrolyte and fluid imbalance

            • Risk factors: Kidney problems | Liver problems | Women | Older adults | Taking higher doses of indapamide | Taking corticosteroids | Parathyroid problems

              Indapamide can cause low levels of fluid (dehydration) and electrolytes (e.g., sodium, potassium, magnesium, or chloride). Sometimes, these changes might worsen liver or kidney problems. If you have severe liver problems, these changes can even result in a coma. Let your provider know if you experience dry mouth, thirst, weakness, tiredness, drowsiness, muscle pain, dizziness, fast heart rate, vomiting, or nausea. These can be symptoms of dehydration.

              Also rarely, taking thiazide-like diuretics, like indapamide, can raise your blood calcium levels. In some cases, this might be a sign of a problem with your parathyroid. If your provider wants to test your parathyroid function, you'll need to stop taking indapamide. Make sure to tell your provider about all the medications you're taking before getting any tests or lab work done.

              risk-warning

              Gout

              • Risk factors: Personal or family history of gout | Kidney problems

                Indapamide can raise uric acid levels in your body and cause or worsen gout. If you have had gout attacks before or have problems with your kidneys, your risk is higher. Talk to your healthcare provider right away if you notice that your joints are swollen, red, and painful.

                risk-warning

                High blood sugar level

                • Risk factor: Diabetes

                  Indapamide might raise your blood sugar. If you already have diabetes, check your blood sugar regularly and let your provider know if it's consistently higher or lower than usual. Your provider will adjust the dose of your diabetic medications as needed.

                  risk-warning

                  Vision problems

                  • Risk factor: Sulfa or penicillin allergies

                    Vision changes can happen within hours or weeks after starting indapamide. Tell your doctor right away about any vision changes or eye pain and stop taking indapamide as soon as possible. In some cases, surgery might be required to avoid permanent vision loss.

                    risk-warning

                    Allergic reactions

                    • Risk factor: Sulfa allergies

                      People with allergies to other sulfa medications might experience similar reactions with indapamide. Make sure your provider and pharmacist know about all of your medication allergies, especially if they are severe. Stop taking indapamide and get medical attention right away if you notice a rash or other signs of allergic reaction.

                      dosage

                      Indapamide dosage forms

                      The average cost for 90 tablets of 1.25mg of Indapamide is $10.00 with a free GoodRx coupon. This is 77.97% off the average retail price of $45.39.
                      tablet
                      Tablet
                      DosageQuantityPrice as low asPrice per unit
                      1.25mg90 tablets$10.00$0.11
                      2.5mg90 tablets$10.00$0.11

                      Typical dosing for Indapamide

                      • High blood pressure: The typical starting dose is 1.25 mg by mouth once daily in the morning. Your provider might adjust your dose depending on how well the medication is working for you. The maximum dose is 5 mg once daily.

                      • Swelling due to heart failure: The typical starting dose is 2.5 mg by mouth once daily in the morning. Your provider might adjust your dose depending on how well the medication is working for you. The maximum dose is 5 mg once daily.

                      interactions

                      Interactions between Indapamide and other drugs

                      Indapamide may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Indapamide. Please note that only the generic name of each medication is listed below.

                      Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                      Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                      • Aminolevulinic Acid
                      • Gossypol
                      • Licorice
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                      contraindications-icon

                      Indapamide contraindications

                      Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Indapamide will not be safe for you to take.

                      • Having trouble urinating

                      • History of allergies to sulfa medications

                      alternatives

                      What are alternatives to Indapamide?

                      There are a number of medications that your doctor can prescribe in place of Indapamide. Compare a few possible alternatives below.
                      Indapamide
                      Used for:

                      • High blood pressure

                      • Swelling (edema) due to heart failure

                      $10.00 Lowest GoodRx priceView Prices
                      Hydrochlorothiazide
                      Used for:

                      • High blood pressure

                      • Swelling in the body from fluids (edema), in addition to other medications

                      $3.00 Lowest GoodRx priceView Prices
                      Furosemide (Lasix)
                      Used for:
                      $1.80 Lowest GoodRx priceView Prices
                      images

                      Indapamide images

                      Orange Round 597 And Logo - Indapamide 1.25mg Tablet
                      This medicine is Orange, Round Tablet Imprinted With "597" And "Logo".Orange Round 597 And Logo - Indapamide 1.25mg Tablet
                      Pink Round M And 69 - Indapamide 1.25mg Tablet
                      This medicine is Pink, Round Tablet Imprinted With "69" And "M".Pink Round M And 69 - Indapamide 1.25mg Tablet
                      Orange Round Ani 510 - Indapamide 1.25mg Tablet
                      This medicine is Orange, Round Tablet Imprinted With "Ani 510".Orange Round Ani 510 - Indapamide 1.25mg Tablet

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                      References

                      Best studies we found

                      Actavis Pharma, Inc. (2023). INDAPAMIDE- indapamide tablet, film coated [package insert]. DailyMed.

                      McCament-Mann, L. A. (n.d.). Benefits and Side Effects of Indapamide. Poison Control.

                      MedlinePlus. (2016). Parathyroid Disorders.

                      View All References (5)

                      Thomas, J. R. (1985). A review of 10 years of experience with indapamide as an antihypertensive agent. Hypertension.

                      Walma, A., et al. (1997). Withdrawal of long term diuretic medication in elderly patients: a double blind randomised trial. BMJ: British Medical Journal.

                      GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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