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Menstrual Disorders: Bleeding, PMS, PMDD, and More

A GoodRx guide to all the things that can go wrong with your menstrual cycle, from cramps and bleeding to moodiness and feeling blue.

Kerry R. McGee, MD, FAAPSophie Vergnaud, MD
Published on March 30, 2021

Although menstrual periods are a normal part of life, people don’t talk about them much. This can leave many of us feeling like we don’t know if our periods are normal — or if they aren’t.

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Reviewed by Alexandra Schwarz, MD | May 31, 2024

Here are some characteristics of a typical menstrual period:

  • A new period starts every 21 to 45 days.

  • Bleeding lasts 2 to 7 days.

  • The amount of bleeding is manageable.

  • Cramps are mild or go away with over-the-counter pain medication.

  • Mood changes and other symptoms don’t interfere with daily activities.

  • Periods start during puberty (around age 12) and stop at menopause (around age 50).

What is premenstrual syndrome (PMS)?

For several days right before your period, the hormone levels in your body are high. This is a normal part of the menstrual cycle, although for some people these hormones can have unpleasant consequences. The effects of these hormones on your body are called premenstrual syndrome, or PMS.

Up to 80% to 90% of people who menstruate experience symptoms leading up to their menstrual periods.

Most people who get periods experience PMS at some point — but it can take different forms in different people, and can affect many different parts of you. It can also change throughout your life. The main thing your symptoms will have in common is that they occur in a monthly pattern that relates to your period. For most people, PMS symptoms kick in about a week before their period, and then gradually get better once their period starts.

Some common symptoms of PMS are:

  • Belly pain or cramps

  • Digestive problems, diarrhea, or bloating

  • Migraines or headaches

  • Feeling tired or having difficulty sleeping

  • Breast tenderness

  • Acne

  • Trouble concentrating

  • Irritability, moodiness, or sadness

Just because PMS is caused by natural hormone changes doesn’t mean you have to put up with it. If you have PMS, there are a variety of straightforward things you can do to make it less of a problem. Prescription solutions are available for many of the symptoms, too.

What are menstrual disorders?

Menstrual disorders happen when your menstrual cycle isn’t happening exactly as it should. Sometimes, this is because of your hormone patterns, and sometimes it’s because of the way your body responds to your hormones. Most menstrual disorders fall into one (or more) of these categories.

Your bleeding is too heavy

This refers to the amount, or volume, of blood that comes out. Bleeding too much is called menorrhagia, and it can go unnoticed if you don't know how much bleeding is normal. Many people with menorrhagia don't realize they’re losing too much blood, and they can become iron-deficient or anemic.

Your periods last too long

If your period bleeding lasts longer than about 8 days, there might be a problem with the lining of your uterus, or with the hormones controlling your cycle.

You’re bleeding when you shouldn’t be

Spotting in between periods might happen occasionally, but it shouldn’t happen all the time. Certain birth control methods, such as Depo-Provera injections and some birth control pills, can cause this — but so can some medical conditions.

You’re not bleeding when you should be

You should get a period every month, unless you’re pregnant, breastfeeding, or taking medication to stop it. If your periods go away unexpectedly, you’ll want to find out why.

The pain is terrible

Menstrual cramps can slow you down, but they shouldn’t keep you from doing the things you want to do. If your abdominal pain is too intense to ignore, that’s not OK.

Mood changes are causing you problems

It’s not unusual to get a little moody, anxious, or distractable during the days leading up to your period. But if you think your emotions are too strong to handle during the week before your period each month, you could be dealing with something bigger.

You have another medical condition that gets worse with your periods

The hormone changes that come with your monthly cycle can cause all kinds of turmoil inside your body. Your period can cause a variety of symptoms that come and go every month, and those can affect your:

  • Mental health

  • Skin

  • Bowel health

  • Neurological health

  • Urinary health

How the menstrual cycle works

Each month, your menstrual cycle is triggered by changes in hormone levels. Here’s how that happens:

  1. Your brain sends a signal.

  2. The signal causes your ovaries to make hormones.

  3. Different parts of your body respond as the hormones rise and then fall.

  4. Your period begins, and the whole cycle starts again.


If your periods don’t follow a regular monthly pattern, or if the hormones are causing you troublesome symptoms, there could be an issue with some part of this process.

It’s normal for your periods to be weird at times in your life when your body is changing. Some of these times are:

  • When you first get your period, and for 2 to 3 years afterward

  • When you are recovering from pregnancy

  • While you are breastfeeding a newborn

  • Following a miscarriage

  • After starting or changing hormone-containing medications (like birth control pills)

  • As you approach menopause (about age 45 to 55)

If you have problems with your menstrual cycle, you’ll want to talk to a healthcare provider about starting a workup. Menstrual cycles are complicated, and many pieces of information might need to come together before you can pin down the correct diagnosis.

Quiz: Do I have endometriosis?

Common menstrual disorders

Problems with your cycle pattern

The problem

Unpredictable bleeding that doesn’t seem to follow a regular pattern is more than just annoying — it’s often a sign of something else going on. It’s OK if your period doesn’t always come exactly when you’d expect, but if you’re going less than 3 weeks, or more than 3 months, between periods, you’ll want to get that checked out.

What it could be

If your periods are random or too close together, the problem might be:

If your periods are too far apart or they’ve stopped altogether (amenorrhea), this could be caused by:

  • Pregnancy (and breastfeeding)

  • PCOS

  • Thyroid problems (overactive or underactive)

  • Over-exercising, poor nutrition, or rapid weight loss

  • Eating disorders

  • Chronic medical conditions

  • Menopause or early menopause

  • Certain medications

  • Stress

What to do about it

A workup might involve measuring hormone levels in your blood. It could also involve an imaging study, such as an ultrasound, to get a better look at your ovaries and uterus.

Problems with bleeding and blood loss

The problem

Heavy menstrual bleeding, or menorrhagia, is when you lose too much blood for a single period. Sometimes, it’s hard to know the difference between what’s usual in general — and what’s usual for you. A typical amount of bleeding for a period is about 30 mL (or 2 tbs). If you need to use several large pads at the same time, or change your pad or tampon every hour or more, your bleeding could be too heavy.

What it could be

If you’re a teenager who’s always had very heavy periods, it’s possible you could have a bleeding disorder like von Willebrand disease. If your periods only became heavy as you aged, a bleeding disorder is less likely. Here are some causes of abnormally heavy periods:

What to do about it

If you’ve had heavy periods for your entire life, you’ll want to get a workup for a bleeding disorder. This might include blood tests and a look into your family history. Sorting out heavy bleeding that started later in life could involve an ultrasound or other imaging studies.

Problems with painful periods

The problem

Painful periods suck. And really painful periods that knock you out for days at a time are a problem. Dysmenorrhea (the medical term for very painful periods) can happen for no reason, but sometimes these are caused by a medical condition.

What it could be
  • Strong — but otherwise normal — period cramps

  • Endometriosis

  • Adenomyosis

  • Fibroids

What to do about it

Any pain that gets in the way of normal life deserves a medical workup. This might include a conversation with your medical provider about your symptoms, a physical exam, and maybe an ultrasound or other imaging study.

Problems with period-related mood changes

The problem

Some people who menstruate experience major mood changes around their periods.

What it could be
  • Premenstrual dysphoric disorder (PMDD) is when a person gets episodes of depression, moodiness, or irritability with their period but not at other times. Symptoms begin several days before a period, last a week or two, and are bad enough to interfere with normal life.

  • Premenstrual exacerbation (PME) is the worsening of another condition due to your hormone cycle. This happens when you have mental health symptoms already, but your period hormones make them worse.

What to do about it

The best way to know if you have a premenstrual mood disorder is to make a calendar. Keep a careful log of which days you have mental health symptoms and which days you don’t. If you can, include a rating of how bad they are. Make sure to note when your period starts. Collect this information every day — even on good days — for a couple months in a row, and look for a pattern linking your moods to your menstrual cycle. Make sure to take the calendar with you when you talk to your healthcare provider.

Treating menstrual disorders

Different menstrual disorders call for different treatments. Some menstrual disorders can be managed with over-the-counter medications and healthy habits. Others require prescription medications, visits to a specialist, or even surgery.

OTC and home remedies

Since people experience menstrual disorders differently, you’ll want to find a strategy that works for you. Here is some general advice to treat PMS and help you feel better when you get your period.

For period cramps:

  • Take ibuprofen (Advil or Motrin) or naproxen (Aleve).

  • Place a heating pad on your belly or lower back.

  • Get some gentle exercise (this helps with migraines and mood symptoms, too).

  • Try acupuncture or acupressure.

  • Start a multivitamin that contains calcium and magnesium.

For bloating and digestive discomfort:

  • Drink plenty of water or juice.

  • Limit high-fat and salty foods.

  • Eat plenty of fruits and vegetables.

  • Switch to small, frequent meals.

For period-related migraines or headaches:

  • Stay hydrated.

  • Avoid caffeine and alcohol.

  • Take acetaminophen (Tylenol) or naproxen (Aleve).

  • Make sure you’re getting enough sleep.

For mild mood symptoms:

  • Try to wake up, eat, and sleep on a regular schedule.

  • Get some exercise every day.

  • Avoid unnecessary stress.

  • Mediate or keep a journal.

  • Stay connected to people who support you.

  • Consider talking to a counselor, therapist, or religious leader.

Here are some other tips to keep in mind:

  • Eating complex carbohydrates and starches can limit cravings and mood symptoms.

  • An iron supplement will help fight fatigue, especially if you tend to get heavy periods.

  • Think ahead and ramp up your skincare regimen or ask your provider about prescription treatments for hormonal acne.

Birth control pills & other hormone medications

Medications that contain hormones — such as birth control pills — are often very helpful for menstrual disorders. When you take them, your body responds by putting its own hormone production on hold.

The daily schedule for these medications causes regular changes in your hormone levels, which puts you in control of your cycle. And because the amount of hormone in the medications is low, taking them lowers the overall hormone levels in your body — and that can reduce or eliminate hormone-related symptoms.

Menstrual suppression

Menstrual suppression is the name for spreading out or stopping your periods with medication. Birth control shots like Depo-Provera, and medication-releasing intrauterine devices (IUDs) like Liletta or Mirena, can be used for menstrual suppression. Many types of birth control pills can also be used to change if, or how often, you get a period. One common schedule allows for a period every 3 months, or just 4 times a year.

Research looking at menstrual suppression has shown that it is safe for most people. In fact, it might even have advantages. If you have a menstrual disorder, menstrual suppression can limit how often you have symptoms. If you’re sexually active, it can double as birth control. And by keeping lifetime hormone levels low, there’s a chance menstrual suppression can reduce the risk of some hormone-dependent cancers.

Antidepressants

Premenstrual mood disorders can often be treated with an antidepressant medication like fluoxetine (Prozac), citalopram (Celexa), or sertraline (Zoloft). This might mean taking medication every day, no matter where you are in your menstrual cycle. For some people, taking antidepressants for just 2 weeks right before each period is enough to get a handle on their symptoms. You’ll want to work closely with a healthcare provider to figure out the best option for you.

PMDD officially became a mental health diagnosis in 2012.

Preventing menstrual disorders

Menstrual disorders are caused by many factors. Genetics play a large role in conditions like endometriosis, bleeding disorders, and mental health problems. Since there’s not much you can do about your genetics, preventing menstrual disorders is hard to do.

Between 3% and 8% of people who menstruate have PMDD.

That being said, it’s helpful to remember that our menstrual cycles are the result of many interconnected systems inside our bodies. Everything we do to stay healthy helps maintain healthy periods, including:

  • Eating right

  • Exercising

  • Maintaining a healthy body weight

  • Getting enough sleep

  • Participating in activities that boost our mood

Getting help

Menstrual periods should not create barriers in your life. If you can’t do the things you want to do because of your periods, or because of the symptoms that come with your periods, it’s time to talk to your healthcare provider.

Too often, people are shy about discussing their menstrual cycles. And many menstrual problems go unrecognized because the people who have them don’t realize their symptoms aren’t normal. It’s important to have honest discussions with your healthcare providers about your body and your menstrual cycles, especially if you have concerns.

Unlike in the past, there are now many new solutions to menstrual problems. Developments in testing and diagnosis can help sort out what’s going on. A variety of medical technologies are being used to deliver effective medications at lower doses than ever before. And we are learning that, for many people, putting a pause on menstrual cycles is safe — and might even come with health benefits.

The bottom line is to stay in touch with your healthcare provider — and with your body. Your menstrual cycle can hold clues to your health. If something doesn’t seem right, it’s worth making the effort to ask.

Keep in mind

Pregnancy can sometimes be confused with menstrual disorders. When you first get pregnant, you might experience:

  • Unexpected bleeding

  • Cramps

  • Nausea

  • Breast tenderness

  • Mood changes

These things can all happen in early pregnancy, even before you’ve missed a period. The timing can make it seem like you’re getting PMS symptoms.

If you’re sexually active and you experience unexpected changes to your cycle, it’s possible that you are pregnant. No birth control method is perfect, so consider taking a home pregnancy test. If it’s negative, wait a couple weeks and take another one. Then, talk to your provider to make sure.

No matter what’s going on, it’s a good idea to pay attention if your periods change unexpectedly. It doesn’t happen often, but sometimes serious medical conditions, like cancer, can first show up as a menstrual disorder. Problem periods can be a sign of something bigger, so don’t wait to talk to your healthcare provider.

Common concerns

When will my periods be normal?

Periods start during puberty. Most people get their first one (menarche) between the ages of 11 and 15. For a couple of years after that, your periods might happen on an unpredictable schedule.

As you reach adulthood, your periods should settle into a monthly pattern. Except for times when you’re pregnant, breastfeeding, or on medications to stop your periods, you should continue to get one period every month until you reach menopause, which happens around age 50.

The time between the ages of 45 and 55 is called perimenopause. During these years it’s normal for your period to change again. This is an important time to be in touch with your healthcare provider about any new menstrual symptoms you might be experiencing.

Can I be prescribed birth control for menstrual disorders without a doctor’s visit?

Years ago, people starting birth control medication for the first time needed a gynecologic or pelvic exam before they could get a prescription for oral contraceptive pills. These days, that requirement has been dropped by most healthcare providers. Still, talking to your provider is a good idea before starting any prescription.

The pros and cons of beginning any new prescription medication should be weighed carefully because, like all medications, birth control pills have possible side effects. For women who smoke, have a history of blood clots or strokes, or have liver disease, the risks might not be worth it.

What other medications can doctors prescribe for menstrual problems?

Depending on the problem, a variety of other medications are used. Thyroid disorders, menstrual migraines, and hormone-triggered acne are all treated with medications that are also used by other people facing these conditions. Some bleeding disorders require specialized medications. And certain menstrual disorders, like polyps or fibroids, might require medical procedures or surgery.

Will I still get menstrual disorders like PMDD if I get pregnant?

Because pregnancy stops the rise and fall of hormones that cause menstrual disorders and PMDD, you can’t technically have these conditions while you’re pregnant. In fact, part of the definition of a menstrual disorder is that it comes and goes with your period. Your menstrual cycle stops when you get pregnant, so menstrual disorders stop, too.

That being said, the hormones that cause menstrual disorders continue to play a role during pregnancy. If those hormones caused problems for you when you weren’t pregnant, it’s possible you’d see similar symptoms when you were — they just wouldn’t follow the same monthly pattern.

Will having a menstrual disorder keep me from getting pregnant?

It depends. Some menstrual disorders, like PCOS or early menopause, can make it difficult to get pregnant. Others, like PMS and PMDD, don’t affect fertility at all — but the medications you take to treat these conditions might. In particular, hormone-containing contraceptives will make it very difficult for you to get pregnant while you’re using them. When you stop using these medications, your fertility will go back to normal.

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Why trust our experts?

Kerry R. McGee, MD, FAAP
Kerry McGee, MD, FAAP, has over a decade of experience caring for babies, children, and teenagers as a primary care pediatrician. She has a special interest in adolescent health, particularly in adolescent mental health.
Sophie Vergnaud, MD
Sophie Vergnaud, MD, is the Senior Medical Director for GoodRx Health. An experienced and dedicated pulmonologist and hospitalist, she spent a decade practicing and teaching clinical medicine at academic hospitals throughout London before transitioning to a career in health education and health technology.

References

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American College of Obstetricians and Gynecologists. (2019). Heavy menstrual bleeding.

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American College of Obstetricians and Gynecologists. (2020). Amenorrhea: Absence of periods.

Arowojolu, A. O., et al. (2012). Effect of birth control pills on acne in women. Cochrane Database of Systematic Reviews.

Centers for Disease Control and Prevention. (2020). What is von Willebrand disease?.

Committee on Adolescent Health Care. (2019). Screening and management of bleeding in adolescents with heavy menstrual bleeding. The American College of Obstetricians and Gynecologists.

Hantsoo, L., et al. (2015). Premenstrual dysphoric disorder: Epidemiology and treatment. Current Psychiatry Reports.

Hantsoo, L. (2019). What is PMDD?. International Association for Premenstrual Disorders.

Hillard, P. A. (2014). Menstrual suppression: Current perspectives. International Journal of Women's Health.

American Academy of Family Physicians. (2016). Premenstrual disorders. American Family Physician.

International Association for Premenstrual Disorders. (2020). What is PME?.

Rapkin, A. J., et al. (2013). Treatment of premenstrual dysphoric disorder. Sage Journals.

Reid, R. L. (2017). Premenstrual dysphoric disorder (formerly premenstrual syndrome). Endotext.

Strandjord, S. E., et al. (2015). Monthly periods—Are they necessary?. Pediatric Annals.

Torkan, B., et al. (2021). The role of water intake in the severity of pain and menstrual distress among females suffering from primary dysmenorrhea: A semi-experimental study. BMC Women's Health.

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