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Geref

sermorelin acetate
Used for Growth Hormone Deficiency
Used for Growth Hormone Deficiency

Geref (sermorelin) is a man-made hormonal medication used for growth problems in children. It can be injected either under the skin or into a vein. Geref (sermorelin) was approved by the FDA in 1997. It has since been discontinued by the manufacturer and is no longer available in the United States.

Reviewed by:
reviewer
Ally Tsai, PharmD
reviewer
Kristianne Hannemann, PharmD
Last reviewed on June 29, 2022
BasicsFAQsAlternativesPricesMedicare
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What is Geref (sermorelin)?

What is Geref (sermorelin) used for?

  • Slow growth in children

How Geref (sermorelin) works

Are you looking for information on Omnitrope (somatropin) instead?

Drug Facts

Common BrandsGeref (brand no longer available)
Drug ClassGrowth hormone releasing factor analog
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityPrescription only
faqs

Frequently asked questions about Geref (sermorelin)

What is Geref (sermorelin)?
Geref (sermorelin) is an injectable medication used for the treatment of slow growth in children. It's a man-made version of the human growth hormone-releasing hormone (GHRH). Geref (sermorelin) mimics GHRH and causes the pituitary gland to release growth hormone (GH), which helps to promote growth in children.
Is Geref (sermorelin) still available?
No, Geref (sermorelin) has been discontinued as of 2008 and is no longer available in the United States.
Why was Geref (sermorelin) discontinued?
The manufacturer (EMD Serono) voluntarily discontinued Geref (sermorelin) due to manufacturing difficulties. It wasn't taken off the market for safety concerns or lack of benefit.
What other medications can my child use instead of Geref (sermorelin)?
Your provider will help guide you to an alternative treatment for your child's growth problems. There are several alternative medications for slow growth in children, including Omnitrope (somatropin) and Increlex (mecasermin). Both of these medications are injected under the skin. They're recombinant medications, which means that they're engineered (created) in a lab to be just like the natural human hormone. Talk with your provider to determine which treatment is best for your child.
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alternatives

What are alternatives to Geref (sermorelin)?

There are a number of medications that your doctor can prescribe in place of Geref (sermorelin). Compare a few possible alternatives below.
Geref (sermorelin)
Used for:

  • Slow growth in children

View Prices
Omnitrope (somatropin)
Used for:
$5138.25 Lowest GoodRx priceView Prices
Increlex (mecasermin)
Used for:
View Prices

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