Growth hormone deficiency occurs when the pituitary gland does not produce enough growth hormone or somatropin. Symptoms in children include slow growth and muscle development, shorter stature than typical, different body composition, and later puberty. Adults can also be affected, with symptoms including reduced bone and muscle mass, lower energy, and increased body fat and cholesterol.
Treatment involves daily injection of recombinant human growth hormones, which can be costly and impact day-to-day life.