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Fluocinolone

Fluocinolone Side Effects

ThienLy Neal, PharmDChristina Aungst, PharmD
Reviewed by ThienLy Neal, PharmD, Christina Aungst, PharmD
Last reviewed on August 31, 2021

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Spider veins (9%)
  • Skin redness (5%)
  • Itching, irritation, or a burning sensation (5%)

Less Common Side Effects

  • Loss of skin color
  • Shiny skin
  • Inflamed hair follicles

Fluocinolone serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Allergic reactions
  • Weakened immune system (from long-term use)

Source: DailyMed

The following Fluocinolone side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Body aches or pain

congestion

cough

dryness or soreness of the throat

fever

headache

hoarseness

lightening of normal skin color

lightening of treated areas of dark skin

sore throat

stuffy or runny nose

tender, swollen glands in the neck

trouble swallowing

unusual tiredness or weakness

voice changes

Less common

Acne or pimples

accumulation of pus

blistering, crusting, irritation, itching, or reddening of the skin

burning, itching, and pain in hairy areas, or pus at the root of the hair

burning and itching of the skin with pinhead-sized red blisters

change in hearing

cracked, dry, scaly skin

diarrhea

dry skin

earache or pain in the ear

ear drainage

flushing or redness of the skin

darkening of the skin

itching, scaling, severe redness, soreness, or swelling of the skin

itchy, raised, round, smooth, skin-colored bumps found on just one area of the body

ooze thick white fluid

raised, dark red, wart-like spots on skin, especially when used on the face

redness or swelling in the ear

skin irritation

skin rash, encrusted, scaly and oozing

spots on your skin resembling a blister or pimple

swelling

swollen, red, tender area of infection

thickened patches of the skin

vomiting

Incidence not known

Redness and scaling around the mouth

thinning, weakness, or wasting away of the skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Changes in skin color

shiny skin

Incidence not known

increased hair growth on the forehead, back, arms, and legs

reddish purple lines on the arms, face, legs, trunk, or groin

softening of the skin

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Why trust our experts?

ThienLy Neal, PharmD, has over 10 years experience in the pharmacy field, including in such settings as retail, hospital, compounding, and managed care. She has led various clinical programs while focusing on medication adherence programs, specialty drug initiatives, and polypharmacy safety initiatives.
Christina Aungst, PharmD, is a pharmacy editor for GoodRx. She began writing for GoodRx Health in 2019, transitioning from freelance writer to editor in 2021.

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