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Fluconazole Coupon - Fluconazole 150mg tablet

fluconazole

Generic Diflucan
Used for Fungal Infection, Thrush, Yeast Infection

Fluconazole is an antifungal medication that veterinarians commonly prescribe off-label to treat certain fungal infections in cats and dogs. This medication comes in tablet and liquid suspension forms that pets take by mouth. The injectable form of the antifungal is only used in veterinary clinics. Side effects of fluconazole in cats and dogs can include vomiting, diarrhea, and poor appetite.

Reviewed by:
reviewerElizabeth Carman, PharmD, FSVHP
reviewerCydnee Ng, PharmD
Last reviewed on February 3, 2025
Paws

For pets

Fluconazole can be prescribed or used off-label by a licensed veterinarian for pets. Medications prescribed for pets aren't intended for human use.

Explore pet medicationsView information for human use
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What is Fluconazole for pets?

What is Fluconazole for pets used for?

How Fluconazole for pets works

Fluconazole is an azole antifungal. It works by destroying the protective outer covering of the fungus that’s causing the infection. The fungus can’t survive when its outer covering gets damaged.

Drug facts

Common BrandsDiflucan
Drug ClassAntifungal
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only
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Side effects of Fluconazole for pets

The following side effects might get better over time as your pet gets used to the medication. Let your veterinarian know immediately if your pet continues to experience these symptoms or if they worsen over time.

Common Side Effects

  • Low appetite
  • Nausea
  • Vomiting
  • Diarrhea

Less Common Side Effects

For dogs:

  • Eye discharge
  • Hair loss
  • Cushing’s syndrome (when the adrenal glands don’t work well, leading to increased thirst and urination, heat sensitivity, and lack of energy)

Fluconazole serious side effects

Contact your veterinarian immediately if your pet experiences any of the following.

  • Liver damage: yellowing of the eyes and skin, vomiting, diarrhea, low appetite or energy

The following Fluconazole side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Rare

Chills

clay-colored stools

cough

dark urine

diarrhea

difficulty with swallowing

dizziness

fast heartbeat

fever

general feeling of tiredness or weakness

headache

hives, itching, or skin rash

large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals

light-colored stools

loss of appetite

nausea

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

stomach pain, continuing

tightness in the chest

unpleasant breath odor

unusual tiredness or weakness

upper right abdominal or stomach pain

vomiting

vomiting of blood

yellow eyes and skin

Incidence not known

Black, tarry stools

blistering, peeling, or loosening of the skin

chest pain or discomfort

decreased urine

dry mouth

fainting

hoarseness

increased thirst

irregular or slow heart rate

joint or muscle pain

loss of bladder control

lower back or side pain

mood changes

muscle pain or cramps

muscle spasm or jerking of the arms and legs

numbness or tingling in the hands, feet, or lips

painful or difficult urination

pale skin

red skin lesions, often with a purple center

red, irritated eyes

seizures

sore throat

sores, ulcers, or white spots in the mouth or on the lips

sudden loss of consciousness

swollen glands

unusual bleeding or bruising

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

Fearfulness, suspiciousness, or other mental changes

seeing, hearing, or feeling things that are not there

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Belching

change in taste or bad, unusual, or unpleasant (after) taste

heartburn

indigestion

stomach discomfort or upset

Incidence not known

Hair loss or thinning of the hair

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Pros and cons of Fluconazole for pets

Pros

  • Different formulations available (tablets or orange-flavored liquid)
  • Can be given with or without food
  • Low chance of side effects

Cons

  • Not the first choice for treating some fungal infections, like ringworm
  • Long treatment time for some infections (weeks to months)
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Pharmacist tips for Fluconazole for pets

pharmacist
  • Your pet can take fluconazole with or without food. If your pet vomits when they take fluconazole on an empty stomach, try giving the medication with food. If they continue vomiting, contact your veterinarian.
  • Vomiting and diarrhea are common side effects of fluconazole. These side effects can put your pet at risk for dehydration. Put bowls of fresh water near areas of your house where your pet often goes to keep them hydrated. Contact your veterinarian if your pet doesn’t stop vomiting or having diarrhea.
  • Be careful to avoid being bit when you’re giving fluconazole to your pet, particularly dogs, that are taking this medication to treat blastomycosis. Although very rare, this fungal infection can spread to humans from dog bites. You won’t get blastomycosis from touching your pet though. Talk to your vet about ways to give this medication if your pet has blastomycosis and tends to bite when you give them medications.
  • Don’t stop giving your pet fluconazole until your vet tells you it’s okay to stop. Stopping this medication before the fungal infection is completely treated can make the infection more difficult to get rid of.
  • Tell your veterinarian if your pet has taken fluconazole before. Fungi can build resistance to the medication if it’s used over and over again to treat infections. This can make infections more difficult to treat.
  • If fluconazole is compounded for your pet, follow the directions that your vet and pharmacist give you about dosing and storage. The information for compounded formulations might be different from the human versions of this medication.

Tips for the liquid suspension form of fluconazole:

  • Store the liquid at room temperature (between 41°F and 77°F). Discard any unused medication after 2 weeks.
  • Don’t use household spoons to measure the dose for your pet since not all spoons are the same size. Use a measuring device like an oral syringe or a dosing cup to measure the dose instead. Ask your vet or pharmacist if you need these measuring devices.
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Risks and warnings for Fluconazole for pets

Fluconazole can cause some serious health issues. This risk might be even higher for certain pets. If this worries you, talk to your veterinarian about other options.

Liver damage

Liver damage can happen in cats and in dogs that take fluconazole. In a study that specifically looked at how fluconazole affects liver function in dogs, some dogs had higher-than-normal liver enzyme levels on their blood test results. Having elevated liver enzyme levels can mean that the liver is irritated. Liver enzyme levels generally go back to normal after the vet lowers the fluconazole dose or after your pet stops taking the medication.

Signs of liver damage to watch out for in cats and dogs include yellowing of their eyes or skin, swelling around the stomach, vomiting, diarrhea, and low appetite or energy. If you notice signs of liver damage in your pet, contact your veterinarian, an emergency veterinarian, or a pet poison hotline immediately.

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Fluconazole dosage forms for pets

The average cost for 2 tablets of 150mg of Fluconazole is $8.69 with a free GoodRx coupon. This is 85.51% off the average retail price of $59.98.
bottle of oral suspensionBottle of oral suspension
DosageQuantityPrice as low asPrice per unit
35ml of 10mg/ml1 bottle$19.49$19.49
35ml of 40mg/ml1 bottle$27.70$27.70
tabletTablet
DosageQuantityPrice as low asPrice per unit
150mg2 tablets$8.69$4.35
100mg7 tablets$8.17$1.17
200mg60 tablets$36.53$0.61
50mg60 tablets$18.86$0.31

Typical dosage for Fluconazole

Fluconazole comes in tablets and a liquid suspension. It can sometimes be made or compounded into a form that fits your pet's needs.

Most times, dosing is based on your pet’s weight. The vet will determine the length of therapy based on the type of fungal infection and your pet’s response to fluconazole.

  • Cats: The dose is usually rounded to 50 mg by mouth every 12 or 24 hours. Your vet might use a different dose for your cat depending on what type of infection it is and how serious it is.

  • Dogs: The typical dose ranges 5 mg/kg to 10 mg/kg by mouth every 12 or 24 hours.

Fluconazole also comes in an injectable form that’s given through your pet’s vein (IV) by a veterinarian or technician.

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Interactions between Fluconazole and other drugs for pets

Fluconazole might interact with certain medications or supplements. Always let your veterinarian know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that your pet is currently taking. The list below does not include all possible drug interactions with Fluconazole. Please note that only the generic name of each medication is listed below.

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

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How much does Fluconazole cost?

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News about Fluconazole

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Fluconazole images

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References

Best studies we found

Aurobindo Pharma Limited. (2024). Fluconazole - fluconazole powder, for suspension [package insert]. DailyMed.

Berlin, D., et al. (2024). Serial evaluation of liver enzyme activities in dogs with pulmonary coccidioidomycosis administered per os fluconazole. Frontiers in Veterinary Science.

Center, S. A. (2024). Enzyme activity in hepatic disease in small animals. Merck Manual Veterinary Manual.

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