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Fluconazole Coupon - Fluconazole 150mg tablet

fluconazole

Generic Diflucan
Used for Yeast Infection, Fungal Infection, Thrush
Used for Yeast Infection, Fungal Infection, Thrush

Fluconazole is an antifungal medication that veterinarians commonly prescribe off-label to treat certain fungal infections in cats and dogs. This medication comes in tablet and liquid suspension forms that pets take by mouth. The injectable form of the antifungal is only used in veterinary clinics. Side effects of fluconazole in cats and dogs can include vomiting, diarrhea, and poor appetite.

Reviewed by:
reviewer
Elizabeth Carman, PharmD, FSVHP
reviewer
Cydnee Ng, PharmD
Last reviewed on February 3, 2025
BasicsSide effectsPros & consPharmacist tipsFAQsWarningsDosageInteractionsCostImagesReferencesPricesMedicare
Paws

For pets

Fluconazole can be prescribed or used off-label by a licensed veterinarian for pets. Medications prescribed for pets aren't intended for human use.

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What is Fluconazole for pets?

What is Fluconazole for pets used for?

How Fluconazole for pets works

Fluconazole is an azole antifungal. It works by destroying the protective outer covering of the fungus that’s causing the infection. The fungus can’t survive when its outer covering gets damaged.

Drug Facts

Common BrandsDiflucan
Drug ClassAntifungal
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only

More on Fluconazole essentials

cat: cat examination 1315171982

Fluconazole for Cats: Get Rid of Fungal Infections Like Ringworm Fast

Written by Sarah J. Wooten, DVM, CVJ
dog: dog at veterinarian 2025553061

Fluconazole for Dogs: A Medication to Treat Fungal Infections

Written by Catherine Barnette, DVM
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What are the side effects of Fluconazole for pets?

The following side effects might get better over time as your pet gets used to the medication. Let your veterinarian know immediately if your pet continues to experience these symptoms or if they worsen over time.

Common Side Effects

  • Low appetite
  • Nausea
  • Vomiting
  • Diarrhea

Other Side Effects

For dogs:
  • Eye discharge
  • Hair loss
  • Cushing’s syndrome (when the adrenal glands don’t work well, leading to increased thirst and urination, heat sensitivity, and lack of energy)

Serious Side Effects

Contact your veterinarian immediately if your pet experiences any of the following.
  • Liver damage: yellowing of the eyes and skin, vomiting, diarrhea, low appetite or energy

The following side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Rare

Chills

clay-colored stools

cough

dark urine

diarrhea

difficulty with swallowing

dizziness

fast heartbeat

fever

general feeling of tiredness or weakness

headache

hives, itching, or skin rash

large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals

light-colored stools

loss of appetite

nausea

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

stomach pain, continuing

tightness in the chest

unpleasant breath odor

unusual tiredness or weakness

upper right abdominal or stomach pain

vomiting

vomiting of blood

yellow eyes and skin

Incidence not known

Black, tarry stools

blistering, peeling, or loosening of the skin

chest pain or discomfort

decreased urine

dry mouth

fainting

hoarseness

increased thirst

irregular or slow heart rate

joint or muscle pain

loss of bladder control

lower back or side pain

mood changes

muscle pain or cramps

muscle spasm or jerking of the arms and legs

numbness or tingling in the hands, feet, or lips

painful or difficult urination

pale skin

red skin lesions, often with a purple center

red, irritated eyes

seizures

sore throat

sores, ulcers, or white spots in the mouth or on the lips

sudden loss of consciousness

swollen glands

unusual bleeding or bruising

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

Fearfulness, suspiciousness, or other mental changes

seeing, hearing, or feeling things that are not there

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Belching

change in taste or bad, unusual, or unpleasant (after) taste

heartburn

indigestion

stomach discomfort or upset

Incidence not known

Hair loss or thinning of the hair

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

pros-and-cons

Pros and cons of Fluconazole for pets

thumbs-up

Pros

Different formulations available (tablets or orange-flavored liquid)

Can be given with or without food

Low chance of side effects

thumbs-down

Cons

Not the first choice for treating some fungal infections, like ringworm

Long treatment time for some infections (weeks to months)

pharmacist-tips

Pharmacist tips for Fluconazole for pets

pharmacist

  • Your pet can take fluconazole with or without food. If your pet vomits when they take fluconazole on an empty stomach, try giving the medication with food. If they continue vomiting, contact your veterinarian.

    • Vomiting and diarrhea are common side effects of fluconazole. These side effects can put your pet at risk for dehydration. Put bowls of fresh water near areas of your house where your pet often goes to keep them hydrated. Contact your veterinarian if your pet doesn’t stop vomiting or having diarrhea.

      • Be careful to avoid being bit when you’re giving fluconazole to your pet, particularly dogs, that are taking this medication to treat blastomycosis. Although very rare, this fungal infection can spread to humans from dog bites. You won’t get blastomycosis from touching your pet though. Talk to your vet about ways to give this medication if your pet has blastomycosis and tends to bite when you give them medications.

        • Don’t stop giving your pet fluconazole until your vet tells you it’s okay to stop. Stopping this medication before the fungal infection is completely treated can make the infection more difficult to get rid of.

          • Tell your veterinarian if your pet has taken fluconazole before. Fungi can build resistance to the medication if it’s used over and over again to treat infections. This can make infections more difficult to treat.

            • If fluconazole is compounded for your pet, follow the directions that your vet and pharmacist give you about dosing and storage. The information for compounded formulations might be different from the human versions of this medication.

              Tips for the liquid suspension form of fluconazole:

              • Store the liquid at room temperature (between 41°F and 77°F). Discard any unused medication after 2 weeks.

                • Don’t use household spoons to measure the dose for your pet since not all spoons are the same size. Use a measuring device like an oral syringe or a dosing cup to measure the dose instead. Ask your vet or pharmacist if you need these measuring devices.

                  faqs

                  Frequently asked questions about Fluconazole for pets

                  Can dogs take fluconazole for an ear infection?
                  It depends whether fluconazole is appropriate and necessary to treat your dog’s ear infection. If your pet has a fungal ear infection, it’s possible that your vet might prescribe fluconazole. Typically, medications like fluconazole are used when the ear infection doesn’t improve with topical medications first. Keep in mind that antifungal medications like fluconazole won’t treat and heal ear infections that are caused by bacteria or viruses; your dog will need other treatment for these types of ear infections. Talk to your vet about treatment options for your dog’s ear infection and how to prevent future ear infections.
                  How long should my dog take fluconazole for a yeast infection?
                  It depends. Your veterinarian will tell you how long to give your dog fluconazole based on what type of fungal infection your pet has and how severe it is. Some infections need only a few days of medication to treat them, while others require weeks or months. You should follow your veterinarian’s directions and make sure your dog completes the entire prescribed course of medication.
                  Is fluconazole safe for dogs?
                  Most dogs can take fluconazole safely, although no medication is 100% safe. Common side effects for dogs are vomiting, low appetite, and diarrhea. But liver damage can be a rare but serious side effect of fluconazole, so the medication should be used cautiously in dogs with liver problems. You should also use fluconazole cautiously in dogs with kidney problems because they can’t get rid of the medication from their body as well. This can cause the medication to stay in the body longer and build up. When dogs have too much fluconazole in their body, they’re at higher risk for serious side effects of the medication. Talk with your vet if you’re concerned about whether fluconazole is safe for your dog.
                  Is fluconazole safe for cats?
                  In general, fluconazole is safe for most cats, although there's a possibility for mild side effects like vomiting, diarrhea, and poor appetite. But the medication can sometimes cause more serious side effects like liver irritation. For this reason, it should be used cautiously in cats with liver problems because of the risk that the liver damage might get worse. In addition, you should use fluconazole cautiously in cats with kidney problems. When the kidneys don’t work as well, fluconazole can stay in the body longer and build up. This can make them more likely to have serious side effects from the medication. Speak with your vet if you have concerns about whether fluconazole is safe for your cat.
                  Is fluconazole for dogs the same as for humans?
                  Fluconazole is a medication that’s FDA approved for people, but it’s also commonly prescribed off-label by vets for treating certain fungal infections in dogs. This is because there aren't any commercially available forms of fluconazole that are specifically approved for dogs. Follow your vet’s directions to give the right amount of this medication to your pet. Don’t rely on dosing information for people because it could be too big of a dose for your dog. Your vet might recommend you to give your dog more than 1 tablet per dose, prescribe the liquid form of the antifungal, or have the medication compounded so your dog gets the dose they need. Ask your vet if you have any questions about giving fluconazole to your dog.
                  Is fluconazole safe for my pet to take with other medications?
                  It depends on what other medications your pet is taking. Fluconazole can interact with many medications like cyclosporine and certain pain medications called nonsteroidal anti-inflammatory drugs (NSAIDs). Interactions that fluconazole can have with other medications can raise the risk of side effects from both medications. Taking interacting medications could also cause fluconazole to not work as well, which could make their fungal infection last longer. Tell your veterinarian and pharmacist about all your pet's medications, supplements, and herbal remedies so they can decide if these medications are safe for your pet to take together.
                  Is fluconazole used to treat ringworm for pets?
                  Fluconazole could treat ringworm in cats and in dogs. But it’s typically not the first-choice treatment option because there are other antifungals that work better to get rid of the fungal infection. Most times, vets will treat ringworm with other oral antifungals like itraconazole for your cat or for your dog along with a topical medication (like chlorhexidine/miconazole) that’s applied directly onto the affected area(s). Speak with your vet about the best option to treat your pet’s ringworm.
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                  What are the risks and warnings for Fluconazole for pets?

                  Fluconazole can cause some serious health issues. This risk might be even higher for certain pets. If this worries you, talk to your veterinarian about other options.

                  risk-warning

                  Liver damage

                  Liver damage can happen in cats and in dogs that take fluconazole. In a study that specifically looked at how fluconazole affects liver function in dogs, some dogs had higher-than-normal liver enzyme levels on their blood test results. Having elevated liver enzyme levels can mean that the liver is irritated. Liver enzyme levels generally go back to normal after the vet lowers the fluconazole dose or after your pet stops taking the medication.

                  Signs of liver damage to watch out for in cats and dogs include yellowing of their eyes or skin, swelling around the stomach, vomiting, diarrhea, and low appetite or energy. If you notice signs of liver damage in your pet, contact your veterinarian, an emergency veterinarian, or a pet poison hotline immediately.

                  dosage

                  Fluconazole dosage forms

                  The average cost for 2 tablets of 150mg of Fluconazole is $1.74 with a free GoodRx coupon. This is 91.45% off the average retail price of $20.35.
                  bottle of oral suspension
                  Bottle of oral suspension
                  DosageQuantityPrice as low asPrice per unit
                  35ml of 10mg/ml1 bottle$12.48$12.48
                  35ml of 40mg/ml1 bottle$22.33$22.33
                  tablet
                  Tablet
                  DosageQuantityPrice as low asPrice per unit
                  50mg60 tablets$18.86$0.31
                  100mg7 tablets$7.14$1.02
                  150mg2 tablets$1.74$0.87
                  200mg60 tablets$35.68$0.59

                  Typical dosing for Fluconazole for pets

                  Fluconazole comes in tablets and a liquid suspension. It can sometimes be made or compounded into a form that fits your pet's needs.

                  Most times, dosing is based on your pet’s weight. The vet will determine the length of therapy based on the type of fungal infection and your pet’s response to fluconazole.

                  • Cats: The dose is usually rounded to 50 mg by mouth every 12 or 24 hours. Your vet might use a different dose for your cat depending on what type of infection it is and how serious it is.

                  • Dogs: The typical dose ranges 5 mg/kg to 10 mg/kg by mouth every 12 or 24 hours.

                  Fluconazole also comes in an injectable form that’s given through your pet’s vein (IV) by a veterinarian or technician.

                  interactions

                  Interactions between Fluconazole and other drugs for pets

                  Fluconazole might interact with certain medications or supplements. Always let your veterinarian know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that your pet is currently taking. The list below does not include all possible drug interactions with Fluconazole. Please note that only the generic name of each medication is listed below.

                  Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

                  Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                  Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

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                  How much does Fluconazole cost?

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                  Diflucan (brand)
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                  images

                  Fluconazole images

                  Pink Oblong C And 10 - Fluconazole 150mg Tablet
                  This medicine is Pink, Oblong Tablet Imprinted With "C" And "10".Pink Oblong C And 10 - Fluconazole 150mg Tablet
                  Pink Oblong C And 10 - Fluconazole 150mg Tablet
                  This medicine is Pink, Oblong Tablet Imprinted With "C" And "10".Pink Oblong C And 10 - Fluconazole 150mg Tablet
                  Pink Round H 603 - Fluconazole 150mg Tablet
                  This medicine is Pink, Round Tablet Imprinted With "H 603".Pink Round H 603 - Fluconazole 150mg Tablet
                  Pink Oval 1139 - Fluconazole 150mg Tablet
                  This medicine is Pink, Oval Tablet Imprinted With "1139".Pink Oval 1139 - Fluconazole 150mg Tablet

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                  References

                  Best studies we found

                  Aurobindo Pharma Limited. (2024). Fluconazole - fluconazole powder, for suspension [package insert]. DailyMed.

                  Berlin, D., et al. (2024). Serial evaluation of liver enzyme activities in dogs with pulmonary coccidioidomycosis administered per os fluconazole. Frontiers in Veterinary Science.

                  Center, S. A. (2024). Enzyme activity in hepatic disease in small animals. Merck Manual Veterinary Manual.

                  View All References (19)

                  Centers for Disease Control and Prevention. (2024). Antimicrobial resistance in people and animals.

                  Centers for Disease Control and Prevention. (2024). Blastomycosis basics.

                  Centers for Disease Control and Prevention. (2024). Risk factors for blastomycosis.

                  Defarges, A., et al. (2024). Disorders of the stomach and intestines in cats. Merck Manual Veterinary Manual.

                  Dowling, P. M. (2024). Drugs used to treat diarrhea in monogastric animals. Merck Manual Veterinary Manual.

                  Dowling, P. M. (2024). Pharmacotherapeutics in fungal urinary tract infections in animals. Merck Manual Veterinary Manual.

                  Gull, T. (2024). Blastomycosis in animals. Merck Manual Veterinary Manual.

                  Gull, T. (2024). Coccidioidomycosis in animals. Merck Manual Veterinary Manual.

                  Gull, T. (2024). Histoplasmosis in animals. Merck Manual Veterinary Manual.

                  Hikma Pharmaceuticals USA Inc. (2024). Fluconazole injection [package insert]. DailyMed.

                  Hobi, S., et al. (2024). Malassezia dermatitis in dogs and cats. The Veterinary Journal.

                  Laporte, C. M., et al. (2017). Quality assessment of fluconazole capsules and oral suspensions compounded by pharmacies located in the United States. American Journal of Veterinary Research.

                  Mercer, M. A. (2024). Azoles for use in animals. Merck Manual Veterinary Manual.

                  Moriello, K. A. (2025). Dermatophytosis in dogs and cats. Merck Manual Veterinary Manual.

                  Patterson, A. P., et al. (2002). How to diagnose and treat Malassezia dermatitis in dogs. Veterinary Medicine.

                  Plumb’s Veterinary Medication Guides. (2020). Fluconazole.

                  Shipstone, M. (2024). Antifungals for integumentary disease in animals. Merck Manual Veterinary Manual.

                  U.S. Food and Drug Administration. (2023). The ins and outs of extra-label drug use in animals: A resource for veterinarians.

                  Webb, C. B. (2024). Vomiting in cats. Merck Manual Veterinary Manual.

                  GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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