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Fetzima

Fetzima Side Effects

Robert Chad Hakim, PharmD, BCCCPCydnee Ng, PharmD
Reviewed by Robert Chad Hakim, PharmD, BCCCP, Cydnee Ng, PharmD
Last reviewed on May 5, 2025

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Nausea (17%)
  • Constipation (9%)
  • Sweating (9%)
  • Fast heart rate (6%)
  • Erectile dysfunction (6%)
  • Vomiting (5%)

Less Common Side Effects

  • Stomach pain
  • Gas
  • Lower appetite
  • Migraine
  • Numbness or tingling
  • Dry eye
  • Dry skin
  • Itching
  • Rash
  • Hot flash
  • Problems with urination (e.g., trouble urinating)
  • Changes in behavior
  • Higher blood pressure

Fetzima serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Suicidal thoughts or behaviors
  • Serotonin syndrome: fever, sweating, movement problems, distress, hallucinations
  • Bleeding or bruising: unusual bleeding or bruising, bleeding or bruising that doesn't go away, nosebleeds, blood in your urine or stool
  • Low sodium levels: headache, trouble concentrating, memory problems, confusion, weakness, unsteadiness, hallucinations, fainting
  • Seizure
When do Fetzima possible side effects begin and end?
Time passed since treatment started:
M
H
D
W
M
Nausea
Fast heart rate
Constipation
Sexual problems
Risk of suicidal thoughts or behaviors
Seek immediate medical care if you experience this side effect.
If a line continues to the right, you'll likely keep experiencing this side effect once it starts.

Source: DailyMed

The following Fetzima side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Difficult urination

fast, pounding, or irregular heartbeat or pulse

Less common

Anxiety

arm, back, or jaw pain

blurred vision

burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

chest pain or discomfort

chest tightness or heaviness

cloudy urine

confusion

decrease in the frequency of urination

difficulty in passing urine (dribbling)

difficulty with speaking

dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position

drooling

dry mouth

fainting

headache

irritability

loss of balance control

muscle trembling, jerking, or stiffness

nausea

painful urination

pounding in the ears

rapid or irregular heartbeat

restlessness

shaking

shuffling walk

slow heartbeat

stiffness of the limbs

sweating

trouble breathing

trouble sleeping

twisting movements of the body

uncontrolled movements, especially of the face, neck, and back

unusual tiredness or weakness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Difficulty having a bowel movement (stool)

increased sweating

loss in sexual ability, desire, drive, or performance

vomiting

Less common

Abdominal or stomach pain

bloated or full feeling

decreased appetite

dry eyes

dry skin

feeling of warmth

headache, severe and throbbing

hives or welts, itching, or rash

passing gas

red eye

red face, neck, arms, and occasionally, upper chest

sudden sweating

thirst

yawning

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Why trust our experts?

Robert Chad Hakim, PharmD, BCCCP, started his full-time career as a clinical pharmacist at UCLA Health in the general medicine, general cardiology, and ICU units after completing residency in 2016. He also was the preceptor for the general medicine rotation from 2017 to 2021, which was a required rotation for all pharmacy residents.
Cydnee Ng, PharmD
Reviewed by:
Cydnee Ng, PharmD
Cydnee Ng, PharmD, is a drug information pharmacist at GoodRx, where she lends her expertise to providing reader-friendly, accessible content about medications. She holds her pharmacist license in California.

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