Skip to main content
Ethyol

Ethyol Side Effects

Ally Tsai, PharmDKristianne Hannemann, PharmD
Reviewed by Ally Tsai, PharmD, Kristianne Hannemann, PharmD
Last reviewed on August 24, 2022

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

The following side effects happened when people received Ethyol (amifostine) with anticancer medications or radiation treatment.

  • Nausea or vomiting (up to 96%)
  • Low blood pressure (up to 62%)

Less Common Side Effects

  • Infusion reactions (e.g., chills, fever, dizziness, blurry vision)
  • Injection site reactions (e.g., rash, itching, hives, skin pain, bruising)

Ethyol serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Serious allergic reaction: fever, chills, chest discomfort, shortness of breath, tightness in throat, hives, swelling
  • Serious skin reactions: rash with blisters, fever, itchy skin, hives, skin pain, skin peeling, skin or mouth sores
  • Serious heart problems: irregular heartbeat, feeling weak, pain in the jaw or back, chest pain

Source: DailyMed

The following Ethyol side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

Blurred vision

confusion

dizziness, faintness, or lightheadedness when suddenly getting up from a lying or sitting position

fainting or loss of consciousness

fast or irregular breathing

itching

nausea, vomiting

red, scaly, swollen, or peeling areas of the skin

skin rash

sweating

swelling of the eyes or eyelids

tightness in the chest

trouble with breathing

unusual tiredness or weakness

Rare

Blistering, peeling, or loosening of the skin

burning or tingling sensation

chills

cough

cracks in the skin

diarrhea

fast, slow, or irregular heartbeat or pulse

fever

joint or muscle pain

loss of bladder control

loss of heat from the body

muscle cramps in the hands, arms, feet, legs, or face

muscle spasm or jerking of all extremities

no blood pressure or pulse

numbness and tingling around the mouth, fingertips, or feet

red, irritated eyes

red skin lesions, often with a purple center

seizures

sore throat

sores, ulcers, or white spots in the mouth or on the lips

stomach cramps

stopping of the heart

sudden loss of consciousness

tremor

Incidence not known

Bloody urine

decreased frequency or amount of urine

difficulty with swallowing

hives or welts

hoarseness

increased blood pressure

increased thirst

lower back or side pain

loss of appetite

pain or discomfort in the arms, jaw, back, or neck

slow or irregular breathing

swelling of the face, fingers, or lower legs

weight gain

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common or rare

Feeling unusually warm or cold

flushing or redness of the face or neck

headache

hiccups

nervousness

pounding in the ears

sleepiness (severe)

sneezing

Incidence not known

Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

GoodRx icon

Other Ethyol articles

GoodRx icon

Other Chemoprotectants side effects articles

Was this page helpful?