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Mesnex

Mesnex Side Effects

Ally Tsai, PharmDKristianne Hannemann, PharmD
Reviewed by Ally Tsai, PharmD, Kristianne Hannemann, PharmD
Last reviewed on October 10, 2024

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Nausea (54-55%)
  • Vomiting (29-38%)
  • Constipation (18-24%)
  • Lower blood cell counts (up to 21%)
  • Feeling tired (20%)
  • Fever (15-20%)
  • Loss of appetite (16-18%)
  • Feeling weak (13-18%)
  • Belly pain (12-15%)
  • Diarrhea (8-14%)

Note: Some side effects listed above might not be from [[EDITOR|DRUG_DISPLAY_NAME]] alone, since studies included people receiving [[EDITOR|DRUG_DISPLAY_NAME]] with ifosfamide (Ifex) and other anticancer medications.

Less Common Side Effects

  • Hair loss
  • Headache
  • Drowsiness
  • Dizziness
  • Chest pain
  • Low potassium levels
  • More sweating
  • Blood in urine
  • Anxiety
  • Injection site reactions
  • Feeling confused
  • Trouble sleeping
  • Coughing
  • Heartburn
  • Pain

Mesnex serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Serious allergic reaction: fast heartbeat, hives, trouble breathing, swelling, joint or muscle pain
  • Serious skin reactions: fever, sore throat, cough, tiredness, rash with blisters, itchy skin, hives, skin pain, puffy eyes, swelling, skin peeling, skin or mouth sores, flushed skin
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Source: DailyMed

The following Mesnex side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

Black, tarry stools

bleeding gums

bloating or swelling of the face, arms, hands, lower legs, or feet

blood in the urine or stools

chest pain

chills

cough

decreased urination

dizziness

dry mouth

fainting

fast, pounding, or irregular heartbeat or pulse

fever

increased thirst

lightheadedness

loss of appetite

mood changes

muscle pain or cramps

nausea

numbness or tingling in the hands, feet, or lips

painful or difficult urination

pinpoint red spots on the skin

rapid breathing

rapid weight gain

seizures

sore throat

sores, ulcers, or white spots on the lips or in the mouth

sunken eyes

swelling

swollen glands

tightness in the chest

trouble breathing

unusual bleeding or bruising

unusual tiredness or weakness

unusual weight gain or loss

vomiting

wrinkled skin

Less common

Blurred vision

confusion

dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position

sweating

Incidence not known

Coughing or spitting up blood

dark urine

general tiredness and weakness

headache

light-colored stools

nervousness

pounding in the ears

slow heartbeat

upper right abdominal or stomach pain

yellow eyes and skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Back pain

bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site

diarrhea

difficulty having a bowel movement

hair loss

increased sweating

lack or loss of strength

sleepiness or unusual drowsiness

stomach pain

trouble sleeping

weight loss

Less common

Belching

feeling of warmth

heartburn

indigestion

redness of the face, neck, arms, and occasionally, upper chest

stomach discomfort or upset

Incidence not known

Change or loss of taste

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Why trust our experts?

Ally Tsai, PharmD
Reviewed by:
Ally Tsai, PharmD
Ally Tsai, PharmD, is a medication therapy management (MTM) pharmacist with 6 years of experience. As an MTM pharmacist, she helps people with complex medication regimens get the best results by conducting comprehensive medication reviews.
Kristianne Hannemann, PharmD, is a licensed pharmacist in California. She has been a retail pharmacy manager and staff pharmacist for over 7 years and has contributed drug information content to different health companies.

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