Is Pediazole (erythromycin / sulfisoxazole) still available?

No. Pediazole (erythromycin / sulfisoxazole) is no longer available as a brand or generic medication in the United States.

Why was Pediazole (erythromycin / sulfisoxazole) discontinued?

It's unknown why Pediazole (erythromycin / sulfisoxazole) was discontinued. It's possible that the manufacturers stopped making the medication because it was no longer needed. According to the [FDA](https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=BasicSearch.process), Pediazole (erythromycin / sulfisoxazole) wasn't discontinued because it was unsafe or didn't work well.

Pediazole

Q: What is Pediazole (erythromycin / sulfisoxazole)?

Pediazole (erythromycin / sulfisoxazole) is a combination of two different medications. [__Erythromycin__](https://www.goodrx.com/erythromycin/what-is) is a [macrolide antibiotic](https://www.goodrx.com/classes/macrolide-antibiotics), while __sulfisoxazole__ is a [sulfonamide (or sulfa)](https://www.goodrx.com/classes/sulfa-antibiotics) antibiotic. Both medications work together to kill bacteria that cause ear infections.

Q: What can I take to replace Pediazole (erythromycin / sulfisoxazole)?

If you used Pediazole (erythromycin / sulfisoxazole) in the past to treat an ear infection, discuss other available treatment options with your healthcare provider. Depending on the nature of the infection, you or your child's provider will help guide you to a medication that's safe to use.

erythromycin / sulfisoxazole

Used for Ear Infection

Pediazole (erythromycin / sulfisoxazole) is used to treat ear infections in children and babies 2 months or older. It's available as a liquid medication that can sometimes cause nausea, vomiting, or stomach pain. This medication is no longer available because it's been discontinued.

Reviewed by:

Shifali Patel, PharmD

Allison Gourley, PharmD

Last reviewed on March 20, 2022

What is Pediazole (erythromycin / sulfisoxazole)?

Are you looking for information on erythromycin pills, erythromycin ointment, or sulfasalazine (Azulfidine) instead?

Drug facts

Common Brands	Pediazole(brand no longer available)
Drug Class	Anti-infective
Controlled Substance Classification	Not a controlled medication
Generic Status	No lower-cost generic available
Availability	Discontinued

Common Brands

Pediazole(brand no longer available)

Drug Class

Anti-infective

Controlled Substance Classification

Not a controlled medication

Generic Status

No lower-cost generic available

Availability

Discontinued

Common questions about Pediazole

Pediazole is a combination of two different medications. Erythromycin is a macrolide antibiotic, while sulfisoxazole is a sulfonamide (or sulfa) antibiotic. Both medications work together to kill bacteria that cause ear infections.

No. Pediazole is no longer available as a brand or generic medication in the United States.

It's unknown why Pediazole was discontinued. It's possible that the manufacturers stopped making the medication because it was no longer needed. According to the FDA, Pediazole wasn't discontinued because it was unsafe or didn't work well.

If you used Pediazole in the past to treat an ear infection, discuss other available treatment options with your healthcare provider. Depending on the nature of the infection, you or your child's provider will help guide you to a medication that's safe to use.

Pediazole

What is Pediazole (erythromycin / sulfisoxazole)?

Are you looking for information on erythromycin pills, erythromycin ointment, or sulfasalazine (Azulfidine) instead?

Drug facts

Common questions about Pediazole

Pediazole (erythromycin / sulfisoxazole) dosage

Typical dosage for Pediazole (erythromycin / sulfisoxazole)

Good news for your inbox

Common questions about Pediazole

What is Pediazole (erythromycin / sulfisoxazole)?

Are you looking for information on erythromycin pills, erythromycin ointment, or sulfasalazine (Azulfidine) instead?

Drug facts

Common questions about Pediazole

What is Pediazole?

Is Pediazole still available?

Why was Pediazole discontinued?

What can I take to replace Pediazole?

Pediazole (erythromycin / sulfisoxazole) dosage

Typical dosage for Pediazole (erythromycin / sulfisoxazole)

Common questions about Pediazole

What is Pediazole?

Is Pediazole still available?

Why was Pediazole discontinued?

What can I take to replace Pediazole?