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Ergotamine/Caffeine

Ergotamine/Caffeine Side Effects

Allison Gourley, PharmDKristianne Hannemann, PharmD
Reviewed by Allison Gourley, PharmD, Kristianne Hannemann, PharmD
Last reviewed on February 15, 2024

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Nausea

Less Common Side Effects

  • Vomiting
  • Heart-related chest pain
  • Muscle pain
  • Fast or slow heartbeat
  • High blood pressure
  • Tingling
  • Numbness
  • Weakness
  • Sensation of room spinning
  • Swelling from fluid buildup
  • Itching
  • Rectal ulcers (suppository only)

Ergotamine/Caffeine serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Stroke: weakness on one side of your body, slurred speech, drooping face
  • Poor blood flow to the hands or feet: pain, numbness, coldness, or pale color in the hands or feet

Source: DailyMed

The following Ergotamine/Caffeine side effects have also been reported

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Burning, pain, tingling, or color changes in the hands, arms, legs, or feet
  • Dry cough, shortness of breath or trouble breathing
  • Heart rhythm changes—fast or irregular heartbeat, dizziness, feeling faint or lightheaded, chest pain, trouble breathing
  • Increase in blood pressure
  • Stroke—sudden numbness or weakness of the face, arm, or leg, trouble speaking, confusion, trouble walking, loss of balance or coordination, dizziness, severe headache, change in vision
  • Sudden or severe stomach pain, bloody diarrhea, fever, nausea, vomiting
  • Pain in the lower back or sides

Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):

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