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Doxazosin

Doxazosin Side Effects

Robert Chad Hakim, PharmD, BCCCPDaisy Chau, PharmD
Reviewed by Robert Chad Hakim, PharmD, BCCCP, Daisy Chau, PharmD
Last reviewed on October 25, 2023

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

Immediate-release tablets

  • Dizziness (16-19%)
  • Fatigue (8-12%)

Extended-release tablets

  • Headache (6%)
  • Dizziness (5%)
  • Respiratory tract infection (5%)
  • Feeling weak (4%)

Less Common Side Effects

Immediate-release tablets

  • Sleepiness
  • Low blood pressure
  • Shortness of breath
  • Dry mouth
  • Swelling

Extended-release tablets

  • Stomach pain
  • Low blood pressure
  • Indigestion
  • Nausea
  • Muscle pain
  • Sleepiness
  • Shortness of breath
  • Urinary tract infection

Doxazosin serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Priapism: painful erection lasting more than 4 hours

Source: DailyMed

The following Doxazosin side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

More common

Dizziness or lightheadedness

Less common

Blurred vision

confusion

dizziness, faintness, or lightheadedness when getting up from a lying or sitting position

fainting (sudden)

fast and pounding heartbeat

irregular heartbeat

shortness of breath

sweating

swelling of feet or lower legs

Rare

Painful or prolonged erection of the penis (called priapism), although extremely rare, must have immediate medical attention. If painful or prolonged erection occurs, call your doctor or go to an emergency room as soon as possible

Incidence not known

Abdominal or stomach pain

area rash

black, tarry stools

bleeding gums

blood in urine or stools

chest pain or discomfort

chills

clay-colored stools

cough

dark urine

diarrhea

difficulty breathing

difficult, burning, or painful urination

fever

general tiredness and weakness

headache, sudden and severe

inability to speak

itching

lab results that show problems with liver

light-colored stools

loss of appetite

noisy breathing

pain or discomfort in arms, jaw, back or neck

pinpoint red or purple spots on skin

rash

seizures

slow or irregular heartbeat

slurred speech

sore throat

sores, ulcers, or white spots on lips or in mouth

swollen glands

temporary blindness

tightness in chest

unpleasant breath odor

unusual bleeding or bruising

upper right abdominal pain

vomiting

vomiting of blood

weakness in arm and/or leg on one side of the body, sudden and severe

wheezing

yellow eyes and skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Headache

lack or loss of strength

unusual tiredness or weakness

Less common

Acid or sour stomach

back pain

belching

bladder pain

cloudy urine

difficulty in moving

frequent urge to urinate

heartburn

indigestion

joint pain

lower back or side pain

muscle aching, cramping, or weakness

muscle pains or stiffness

nausea

nervousness, restlessness, unusual irritability

runny nose

sleepiness or drowsiness

sneezing

sore throat

stomach discomfort, upset or pain

swollen joints

Incidence not known

Anxiety

burning, crawling, itching, numbness, prickling, “pins and needles”, or tingling feeling

change in frequency or urination

dry mouth

feeling of warmth

frequent urination

general feeling of discomfort or illness

hair loss

hives or welts

hyperventilation

increased urge to urinate during the night

increased volume of pale dilute urine

loss of appetite

painful urination

redness of skin

redness of the face, neck, arms and occasionally upper chest

shaking

swelling of the breasts or breast soreness in both females and males

thinning of hair

trouble in holding or releasing urine

trouble sleeping

waking to urinate at night

weight loss

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Why trust our experts?

Robert Chad Hakim, PharmD, BCCCP, started his full-time career as a clinical pharmacist at UCLA Health in the general medicine, general cardiology, and ICU units after completing residency in 2016. He also was the preceptor for the general medicine rotation from 2017 to 2021, which was a required rotation for all pharmacy residents.
Daisy Chau, PharmD
Reviewed by:
Daisy Chau, PharmD
Daisy Chau, PharmD, is the drug information pharmacist manager at GoodRx. She is licensed in California and has more than 6 years of experience working as a pharmacist in drug information.

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