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Embeda

morphine / naltrexone
Used for Pain

Morphine/naltrexone is a strong pain medication used for daily, around-the-clock pain control. It's a combination medication that commonly causes sleepiness, dizziness, and constipation. It's been discontinued in the United States.

Reviewed by:
reviewerShifali Patel, PharmD
reviewerMichelle Nguyen, PharmD
Last reviewed on January 11, 2022
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What is Morphine/naltrexone?

Drug facts

Common BrandsEmbeda(brand no longer available)
Drug ClassOpioid agonist / Antagonist
Controlled Substance ClassificationSchedule II
Generic StatusNo lower-cost generic available
AvailabilityDiscontinued
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Common questions about Morphine/naltrexone

Morphine/naltrexone is a combination medication used to treat moderate-to-severe pain in people who need long-term pain control. Morphine is an opioid that binds to certain parts of your brain to change how you react to pain. This helps lower how much pain you feel. Naltrexone is an opioid antagonist that blocks opioid receptors in your brain to prevent the harmful effects of opioids, such as slowed breathing, extreme sleepiness, and low blood pressure. Morphine/naltrexone shouldn't be used for short-term pain control, and it should only be used if other pain medications have failed to work for you in the past.

No. Morphine/naltrexone is no longer available as a brand or generic medication in the United States.

It's unknown why morphine/naltrexone was discontinued by its manufacturer and the U.S. Food and Drug Administration (FDA) hasn't stated the reason for discontinuation. It's possible that it was removed from the market because it was no longer needed.

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Morphine/naltrexone dosage

Typical dosage for Morphine/naltrexone

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Interactions between Morphine/naltrexone and other drugs

Morphine/naltrexone may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Morphine/naltrexone. Please note that only the generic name of each medication is listed below.

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

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