Prescription Prices and Coupons from GoodRx
Type your drug name (like Atorvastatin, Sildenafil, etc)
ESTRADIOL contains the female hormone estrogen. It is used for symptoms of menopause like hot flashes, night sweats, and mood changes. This medicine may also help relieve other symptoms like vaginal dryness, itching and increased or painful urination. Compare estrogens.
Prescription Settings
gel pump
35g of 0.06%
1 gel pump
gel pump
35g of 0.06%
1 gel pump

Elestrin Side Effects

What should I watch for?

Visit your health care professional for regular checks on your progress. You will need a regular breast and pelvic exam. You should also discuss the need for regular mammograms with your health care professional, and follow his or her guidelines.

This medicine can make your body retain fluid, making your fingers, hands, or ankles swell. Your blood pressure can go up. Contact your doctor or health care professional if you feel you are retaining fluid.

If you have any reason to think you are pregnant; stop taking this medicine at once and contact your doctor or health care professional.

Tobacco smoking increases the risk of getting a blood clot or having a stroke, especially if you are more than 35 years old. You are strongly advised not to smoke.

If you wear contact lenses and notice visual changes, or if the lenses begin to feel uncomfortable, consult your eye care specialist.

If you are going to have elective surgery, you may need to stop taking this medicine beforehand. Consult your health care professional for advice prior to scheduling the surgery.


Common and Rare Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Incidence not known

Abdominal or stomach cramps or pain

acid or sour stomach




blistering, peeling, or loosening of the skin


blurred vision

breast tenderness, enlargement, pain, or discharge

change in vaginal discharge

changes in skin color

changes in vision

chest pain or discomfort


clay-colored stools

clear or bloody discharge from the nipple





darkening of the urine


difficulty with breathing

difficulty with swallowing

dimpling of the breast skin

dizziness or lightheadedness

double vision


fast heartbeat


fluid-filled skin blisters

full or bloated feeling or pressure in the stomach


headache, severe and throbbing



inverted nipple

irregular heartbeat

itching of the vagina or genital area

joint or muscle pain

large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs

light-colored stools

loss of appetite

loss of bladder control

lump in the breast or under the arm

migraine headache

mood or mental changes

muscle cramps in the hands, arms, feet, legs, or face

muscle spasm or jerking of all extremities


noisy breathing

numbness and tingling around the mouth, fingertips, or feet

pain during sexual intercourse

pain in the ankles or knees

pain or discomfort in the arms, jaw, back, or neck

pain or feeling of pressure in the pelvis

pain, redness, or swelling in the arm, foot, or leg

painful, red lumps under the skin, mostly on the legs

pains in the stomach, side, or abdomen, possibly radiating to the back

persistent crusting or scaling of the nipple

poor insight and judgment

problems with memory or speech

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

rash, hives, or itching

red, irritated eyes

redness or swelling of the breast

sensitivity to the sun

skin thinness

sore on the skin of the breast that does not heal

sore throat

sores, ulcers, or white spots in the mouth or on the lips

stomach discomfort, upset, or pain

sudden loss of consciousness

sudden shortness of breath or troubled breathing



swelling of the abdominal or stomach area

thick, white vaginal discharge with no odor or with a mild odor

tightness in the chest


trouble recognizing objects

trouble thinking and planning

trouble walking

unexpected or excess milk flow from the breasts

unpleasant breath odor

unusual tiredness or weakness

unusually heavy or unexpected menstrual bleeding

vaginal bleeding or spotting


vomiting of blood

yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Back pain

difficulty with moving

muscle aches

muscle pain or stiffness

stuffy or runny nose

Incidence not known

Decreased interest in sexual intercourse

heavy bleeding

hives or welts

inability to have or keep an erection

increased hair growth, especially on the face

increased in sexual ability, desire, drive, or performance

increased interest in sexual intercourse


leg cramps

loss in sexual ability, desire, drive, or performance

loss of scalp hair

mental depression

mood disturbances

patchy brown or dark brown discoloration of the skin

redness of the skin

twitching, uncontrolled movements of the tongue, lips, face, arms, or legs

weight changes

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Copyright ©2018 GoodRx, Inc.
GoodRx is not sponsored by or affiliated with any of the pharmacies identified in its price comparisons. All trademarks, brands, logos and copyright images are property of their respective owners and rights holders and are used solely to represent the products of these rights holders. This information is for informational purposes only and is not meant to be a substitute for professional medical advice, diagnosis or treatment. GoodRx is not offering advice, recommending or endorsing any specific prescription drug, pharmacy or other information on the site. GoodRx provides no warranty for any of the pricing data or other information. Please seek medical advice before starting, changing or terminating any medical treatment.
In all states except Tennessee, GoodRx is considered a marketer of prescription discount cards, and is not required to register as a discount card provider. In Tennessee, GoodRx is registered as a Prescription Drug Discount Plan Operator.
LegitScript SealNABP SealBBB Seal
The information contained in the Truven Health Micromedex products as delivered by GoodRx is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.
The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Truven Health and GoodRx make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Truven Health does not assume any responsibility or risk for your use of the Truven Health products.