The GoodRx Top 10 (May 2017)

Several times a year, GoodRx creates a list of the most-dispensed prescriptions in the U.S. To form our list, we look at a sample of claims as reported by pharmacies across the country. We combine prescriptions for brands and generics; we also display the GoodRx Fair Price for the most common form, dosage and quantity.

Rank Drug GoodRx Fair Price
White Oblong M365 - Hydrocodone Bitartrate/Acetaminophen 5mg-325mg Tablet
Vicodin, Norco, Xodol (hydrocodone/acetaminophen)
14 See Prices
The combination of hydrocodone and acetaminophen (Vicodin, Norco, Xodol, Lorcet, Lortab) is used to treat moderate to severe pain, from a variety of causes. Hydrocodone is an opiate and is considered a narcotic pain medicine, while acetaminophen (Tylenol) is also sold over the counter for pain. Other opioid and acetaminophen combinations are available, but hydrocodone and acetaminophen is the most popular. This may change now that the FDA has reclassified hydrocodone and acetaminophen as a schedule 2 controlled substance with more restrictions.
White Oblong L 5 And M - Levothyroxine Sodium 50mcg Tablet
Synthroid, Levoxyl, Unithroid (levothyroxine)
Drug Class: Thyroxines
11 See Prices
Levothyroxine (Synthroid, Unithroid, Levoxyl, Levothroid) is a synthetically prepared thyroid hormone that can improve symptoms of thyroid deficiency. There are several brand and generic levothyroxine choices available; however, they aren't interchangeable. Generic levothyroxine is very inexpensive, though most of the brands available are also affordable.
White Round 54 760 - Prednisone 20mg Tablet
Delasone, Sterapred (prednisone)
Drug Class: Corticosteroids
5 See Prices
Prednisone (Sterapred, Deltasone) is a synthetic corticosteroid used to treat a very wide variety of conditions, and is effective as an immunosuppressant. Corticosteroids can have some major side effects, but they are one of the oldest and most effective treatments for several conditions, and prednisone was one of the first introduced.
Yellow Amox 500 Gg 849 - Amoxicillin 500mg Capsule
Amoxil (amoxicillin)
9 See Prices
Amoxicillin (Amoxil) is a penicillin antibiotic used to treat many different types of bacterial infections. It is one of the most commonly prescribed antibiotics for children, and is offered for free or at a reduced cost under many pharmacies' discount generic programs.
Yellow D 03 - Gabapentin 300mg Capsule
Neurontin (gabapentin)
Drug Class: Anti-epileptics
11 See Prices
Gabapentin (Neurontin) is an anti-epileptic drug also approved to relieve some types of nerve pain, including pain from shingles (postherpetic neuralgia).
Pink Round Lupin And 20 - Lisinopril 20mg Tablet
Prinivil, Zestril (lisinopril)
Drug Class: ACE Inhibitors
7 See Prices
Lisinopril (Prinivil, Zestril) is an ACE inhibitor used to treat high blood pressure, and in combination with other medications to treat heart failure. Lisinopril was the third ACE inhibitor to become available. It may be more convenient than some of the other options because it is longer-acting, meaning you only need to take one tablet per day rather than two or three.
White Oval Rx 829 - Atorvastatin Calcium 40mg Tablet
Lipitor (atorvastatin)
Drug Class: Statins
11 See Prices
Atorvastatin (Lipitor) is a statin used to treat high cholesterol. Prior to its release as generic atorvastatin in 2011, it was considered the top drug by sales for most of the previous decade. It is still one of the most commonly prescribed statins, and though not as inexpensive as simvastatin (Zocor), the generic price has continued to drop.
White Round 234 And M - Metformin Hydrochloride 500mg Tablet
Glucophage (metformin)
Drug Class: Biguanides
8 See Prices
Metformin (Glucophage) is a biguanide used in combination with diet and exercise to help control blood sugar levels in type 2 diabetes. It is a first-line drug, meaning it is often tried before other treatment options, and it may be used alone or with other medications. Metformin is believed to be the most widely prescribed diabetes medication in the world and it is available as a very inexpensive generic in the US. Many pharmacies offer it for free or at a reduced cost under their discount generic programs.
White Round 153 And R - Ondansetron Hydrochloride 4mg Tablet
Zofran (ondansetron)
Drug Class: Serotonin Antagonists
11 See Prices
Ondansetron (Zofran) was the first selective serotonin blocking agent available to treat nausea. It is an extremely safe and highly effective antiemetic that has greatly improved the ability to give chemotherapy. Patients’ quality of life is superior with ondansetron than with older, traditional antiemetics like prochlorperazine (Compazine). Ondansetron is available as a tablet or an orally disintegrating tablet (ODT), which does not require water to aid in swallowing. The dissolvable tablet is easier to take if you can’t keep a pill down for 20 minutes, and ondansetron tablets and ODT are bioequivalent (essentially the same).
White Oblong Ip 466 - Ibuprofen 800mg Tablet
Motrin (ibuprofen)
Drug Class: NSAIDs
12 See Prices
Ibuprofen (Motrin, Motrin IB, Advil) is a non-steroidal anti-inflammatory drug (NSAID) used to treat fever, pain from arthritis, menstrual cramps, and muscular aches. It is available both over-the-counter and by prescription depending on the strength. Many people use ibuprofen to relieve any type of pain or take it preventatively, but ibuprofen should be used only when needed as it may increase risk of stroke or heart attack and long term use can cause stomach bleeding and ulcers.

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