The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Flushing (40%)
- Stomach pain (18%)
- Diarrhea (14%)
- Nausea (12%)
- Vomiting (9%)
- Itchiness (8%)
- Rash (8%)
Less Common Side Effects
- Redness of the skin
- Upset stomach or indigestion
- Higher liver enzyme levels on blood test results
- Low white blood cell count
Dimethyl Fumarate serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Liver damage: fever, feeling tired, nausea, vomiting, yellowing of the skin or whites of the eyes, clay-colored stool, dark urine
- Serious infection: fever, cough, weakness, difficulty speaking or thinking, muscle pain, changes in personality, confusion
- Stomach or gut issues: rectal bleeding, bloody diarrhea, severe vomiting or diarrhea, severe stomach pain
- Serious allergic reaction: difficulty breathing, rash, swelling of lips or tongue
Source: DailyMed
The following Dimethyl Fumarate side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
More common
Chills
feeling of warmth
hoarseness
lower back or side pain
painful or difficult urination
redness of the face, neck, arms, and occasionally, upper chest
Incidence not known
Black, tarry stools
difficulty with swallowing
dizziness
fast heartbeat
large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals
painful blisters on the trunk of the body
puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
sores, ulcers, or white spots on the lips or in the mouth
swollen glands
tightness in the chest
trouble breathing
unusual bleeding or bruising
unusual tiredness or weakness
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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