The average cost for 1 nasal spray of 8 vials of 4mg/ml of Dihydroergotamine Mesylate is $275.33 with a free GoodRx coupon. This is 90.74% off the average retail price of $2,974.67.
Dosage | Quantity | Price as low as | Price per unit |
|---|---|---|---|
1ml of 1mg/ml | 20 ampules | $290.80 | $14.54 |
Dosage | Quantity | Price as low as | Price per unit |
|---|---|---|---|
10 ampules of 1mg/ml | 1 carton | $199.00 | $199.00 |
10 vials of 1mg/ml | 1 carton | $407.80 | $407.80 |
Dosage | Quantity | Price as low as | Price per unit |
|---|---|---|---|
1ml of 4mg/ml | 8 vials | $275.33 | $34.42 |
Dosage | Quantity | Price as low as | Price per unit |
|---|---|---|---|
8 vials of 4mg/ml | 1 nasal spray | $275.33 | $275.33 |
Typical dosage for Dihydroergotamine Mesylate
Nasal spray
- Dihydroergotamine (Migranal): The typical dose is one spray (0.5 mg) in each nostril. If needed, you can repeat the dose after 15 minutes, for a total of four sprays (2 mg). Don't use more than six sprays (3 mg) in a 24-hour period or eight sprays (4 mg) within a 7-day period.
- Trudhesa (dihydroergotamine): The typical dose is one spray (0.725 mg) in each nostril. If needed, you can repeat the dose at least 1 hour after the first dose. Don't use more than two doses in a 24-hour period or three doses in a 7-day period.
Injection
- Dihydroergotamine (D.H.E. 45): The typical dose is 1 mg injected intramuscularly (into your muscle) or subcutaneously (under your skin) for a one-time dose. If needed, you can repeat the dose at least 1 hour after the first dose. Don't use more than three doses (3 mg) in a 24-hour period or more than six doses (6 mg) within a 7-day period.
- Dihydroergotamine (D.H.E. 45) is also available as an intravenous (IV) infusion through your vein that's administered by a healthcare provider.
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Why trust our experts?

Reviewed by:
Aileen Chu, PharmD, BCPSAileen Chu, PharmD, has over 8 years of experience working as a clinical pharmacist in the emergency department. Chu is also a pharmacotherapeutics instructor at Point Loma Nazarene University.

Reviewed by:
Kristianne Hannemann, PharmDKristianne Hannemann, PharmD, is a licensed pharmacist in California. She has been a retail pharmacy manager and staff pharmacist for over 7 years and has contributed drug information content to different health companies.

