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Dihydroergotamine Mesylate

Dihydroergotamine Mesylate Dosage

Aileen Chu, PharmD, BCPSKristianne Hannemann, PharmD
Reviewed by Aileen Chu, PharmD, BCPS, Kristianne Hannemann, PharmD
Last reviewed on February 22, 2022

The average cost for 1 nasal spray of 8 vials of 4mg/ml of Dihydroergotamine Mesylate is $275.33 with a free GoodRx coupon. This is 90.74% off the average retail price of $2,974.67.

ampuleAmpule

Dosage

Quantity

Price as low as

Price per unit

1ml of 1mg/ml

20 ampules

$290.80

$14.54

cartonCarton

Dosage

Quantity

Price as low as

Price per unit

10 ampules of 1mg/ml

1 carton

$199.00

$199.00

10 vials of 1mg/ml

1 carton

$407.80

$407.80

vialVial

Dosage

Quantity

Price as low as

Price per unit

1ml of 4mg/ml

8 vials

$275.33

$34.42

nasal sprayNasal spray

Dosage

Quantity

Price as low as

Price per unit

8 vials of 4mg/ml

1 nasal spray

$275.33

$275.33

Avg retail price
$2,974.67(Save 90.94%)
GoodRx discount
$269.43
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Typical dosage for Dihydroergotamine Mesylate

Nasal spray

  • Dihydroergotamine (Migranal): The typical dose is one spray (0.5 mg) in each nostril. If needed, you can repeat the dose after 15 minutes, for a total of four sprays (2 mg). Don't use more than six sprays (3 mg) in a 24-hour period or eight sprays (4 mg) within a 7-day period.
  • Trudhesa (dihydroergotamine): The typical dose is one spray (0.725 mg) in each nostril. If needed, you can repeat the dose at least 1 hour after the first dose. Don't use more than two doses in a 24-hour period or three doses in a 7-day period.

Injection

  • Dihydroergotamine (D.H.E. 45): The typical dose is 1 mg injected intramuscularly (into your muscle) or subcutaneously (under your skin) for a one-time dose. If needed, you can repeat the dose at least 1 hour after the first dose. Don't use more than three doses (3 mg) in a 24-hour period or more than six doses (6 mg) within a 7-day period.
  • Dihydroergotamine (D.H.E. 45) is also available as an intravenous (IV) infusion through your vein that's administered by a healthcare provider.
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Why trust our experts?

Aileen Chu, PharmD, has over 8 years of experience working as a clinical pharmacist in the emergency department. Chu is also a pharmacotherapeutics instructor at Point Loma Nazarene University.
Kristianne Hannemann, PharmD, is a licensed pharmacist in California. She has been a retail pharmacy manager and staff pharmacist for over 7 years and has contributed drug information content to different health companies.

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