Skip to main content
Dalfampridine ER

Dalfampridine ER Side Effects

Robert Chad Hakim, PharmD, BCCCPCydnee Ng, PharmD
Reviewed by Robert Chad Hakim, PharmD, BCCCP, Cydnee Ng, PharmD
Last reviewed on May 1, 2023

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Urinary tract infection (12%)
  • Insomnia (trouble sleeping, 9%)
  • Dizziness (7%)
  • Headache (7%)
  • Nausea (7%)
  • Weakness or lack of energy (7%)

Less Common Side Effects

  • Back pain
  • Balance problems
  • MS relapse
  • Burning or prickling feeling in your hands and feet
  • Runny nose or other common cold symptoms
  • Constipation
  • Upset stomach

Dalfampridine ER serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Severe allergic reactions: hives, rash, red skin, swelling of the lips or tongue, closing of the throat, difficulty breathing
  • Seizures

Source: DailyMed

The following Dalfampridine ER side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Bladder pain

bloody or cloudy urine

difficult, burning, or painful urination

frequent urge to urinate

lower back or side pain

Less common

Blurred vision

burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

difficulty controlling your bladder or bowels

difficulty walking

feeling sad or depressed

forgetful

muscle cramps

problems with swallowing

slurred speech

unusual tiredness or weakness

Incidence not known

Cough

dizziness

fast heartbeat

hives, itching, skin rash

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

tightness in the chest

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

Confusion

epileptic seizure that will not stop

increased sweating

memory loss

reduced awareness

seizures

weakness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Headache

lack or loss of strength

nausea

trouble sleeping

Less common

Back pain

constipation

fever

muscle aches

sore throat

stuffy or runny nose

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

GoodRx icon

Other Potassium Channel Blockers side effects articles

Was this page helpful?