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Dacarbazine Medicare coverage

Used for Melanoma, Hodgkin Lymphoma

Dacarbazine Coupon - Dacarbazine 10ml of 100mg vial

Dacarbazine is a chemotherapy medication called an alkylating agent. It's mainly used to treat Hodgkin’s lymphoma (also called Hodgkin’s disease). This medication is also approved for melanoma, a type of skin cancer. Dacarbazine doses are given at an infusion center or clinic as an injection into the vein (intravenous or IV). Possible side effects include nausea, loss of appetite, and low blood cell counts. Dacarbazine is a generic medication; the brand name DTIC-Dome is no longer available.

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Annual Notice of Change (ANOC):

The Medicare Annual Notice of Change (ANOC) is a letter for people enrolled in Medicare Advantage plans and anyone with Medicare Part D prescription coverage. People with Medicare Advantage or original Medicare (Part A and/or Part B) can have Part D plans. The ANOC informs enrollees about any changes to their benefits for the coming coverage year. By law, Medicare Advantage and Part D plans must send the ANOC to enrollees by September 30 — which is before the annual Medicare open enrollment period of October 15 to December 7. Even if you have the same plan, your benefits could change year to year.

Premium:

A premium is the cost of having a health insurance plan and is usually paid monthly. Medicare enrollees may pay several premiums. Most people don’t pay anything for Part A hospital insurance, but some people do depending on how long they worked and paid taxes. For outpatient and preventive coverage, the Part B standard premium is $185 a month in 2025, but people with higher incomes pay more. Your premium for Medicare Advantage plans will vary, but even so-called “zero premium” plans require you to pay your Part B premium. Part D premiums range in price, but the average is about $47 a month in 2025. If you have original Medicare and a Medigap supplement plan, you have an additional premium for that coverage.

Deductible:

A deductible is the amount you pay out of pocket before your Medicare plan begins cost-sharing. In 2025, the Part A deductible is $1,676 per benefit period. The Part B deductible is $257 for the year, but you can access certain preventive care — including some vaccines — without meeting your deductible. Medicare Advantage deductibles vary and your Part D deductible can’t exceed $590 in 2025.

Out-of-pocket limit:

Original Medicare has no annual out-of-pocket maximum. Medicare Advantage plans have out-of-pocket limits. In 2025, they are $9,350 for in-network covered services and $14,000 for in-network and out-of-network covered services combined.

Medicare Prescription Payment Plan:

Starting January 1, 2025, anyone with Part D coverage had the option to use the Medicare Prescription Payment Plan for their out-of-pocket medication costs instead of paying upfront at the pharmacy. This plan doesn’t provide savings, but allows you to spread prescription costs — including your deductible — over the year. Making payments can be particularly helpful for people who may skip or delay picking up prescriptions because of high costs early in the year. Also in 2025, the Part D out-of-pocket limit dropped to $2,000.

Initial coverage phase:

After a Medicare enrollee meets the Part D deductible (if the plan has one), the health insurance begins cost sharing. The initial coverage phase means you pay coinsurance or a copay for covered prescriptions.

Catastrophic phase:

When you reach the $2,000 out-of-pocket maximum, your Part D plan pays for 100% of covered medications for the rest of the year.

Medication ready
How to save on drugs with Medicare

Medicare Part D is the part of Medicare that helps cover prescription medications, including both brand name and generic. It also includes coverage for certain vaccines that aren’t covered by Part B, as well as some medical supplies.

Even with Medicare Part D coverage, you may still have out-of-pocket costs such as premiums, deductibles, copayments, and coinsurance. As of 2025, Medicare Part D plans include a $2,000 annual out-of-pocket cap. Once you reach this limit, your plan covers the full cost of your covered medications for the rest of the year.

Still, there are several ways to reduce your prescription medication cost. From GoodRx coupons to patient assistance programs, here are ways you can save money on the medications you need.

1. See if you qualify for Medicare’s Extra Help program

The Medicare Extra Help/Low-Income Subsidy program is a federally funded program for people covered under a Medicare Part D plan. It helps reduce enrollees’ out-of-pocket costs by limiting their deductibles and copays. To qualify, your income and assets fall below a certain limit.

If you’re eligible, you may receive:

  • No monthly premiums for Medicare Part D

  • No Medicare Part D deductible

  • Low copays for prescription medications

2. Use GoodRx coupons

You can’t combine GoodRx coupons with Medicare, but you can choose to use a coupon instead of your insurance if it results in a lower price.

Here’s how to download a GoodRx coupon:

  1. Go to the GoodRx website, or download the GoodRx app on your phone.

  2. Search for your prescription medication.

  3. Enter your prescribed dose and quantity, then set your location.

  4. Compare prices across different pharmacies in your area.

  5. Click “Find the lowest prices” or press “Enter.”

  6. You can have the coupon sent by text or email, or print it out.

  7. To apply the discount, show the coupon at the pharmacy when you fill your prescription. Ideally, this is done at drop-off before the prescription is filled.

3. Consider the Medicare Prescription Payment Plan

The Medicare Prescription Payment Plan is a new program that can help make paying for medications more manageable. It’s open to anyone with a standalone Part D plan or those with Medicare Advantage plans that offer prescription medication coverage.

There is no cost to participate in the Medicare Prescription Payment Plan and participation is voluntary. Instead of paying for the total cost of your medications up front at the pharmacy, the payment plan allows you to spread the cost into smaller payments during the year. If you join, you will continue to pay your premium every month as well as an additional monthly amount on your payment plan. It’s a good idea to review how the Medicare Prescription Payment Plan works to determine if it’s right for you.

4. Compare Part D plans during open enrollment

Medicare open enrollment, which takes place every year from October 15 to December 7, is your chance to switch plans if another option offers better prescription medication coverage or lower costs. Plan costs and coverage details can change each year, so it’s important to review your options.

Here are some steps to help you compare plans:

  1. Make a list of all your medications and what dosages you take.

  2. Enter the names of your prescription medications to see which plans offer the best coverage.

  3. Look at premiums, deductibles, and medication costs for each plan. Plans usually change their formularies, premiums, and copays annually.

  4. Check if your preferred pharmacy is in each plan's network.

5. Get a 90-day supply

Opting for a 90-day supply instead of a monthly refill of your medication might help reduce your long-term out-of-pocket costs. Many insurance plans offer lower copays or bulk pricing for 3-month prescriptions.

If your medication is covered under your plan, see if your insurer’s mail-order or specialty pharmacy provides savings on a 90-day supply. If they do, ask your prescriber to write a prescription for a 90-day quantity to take advantage of these potential savings.

6. Ask about the generic version of your medication

Some medications have a generic version, and they generally cost less than the brand-name prescriptions. Generic medications are just as safe and effective as brand-name medications, so it’s an option worth considering to reduce your cost. Ask your prescriber about switching to a generic version of your medication to save money.

7. Consider lower-cost alternative medications

There may be other medications that help manage your condition, and they may cost less. If your medication is costly or not covered by your insurance, talk to your prescriber about lower-cost alternatives that might be a good option for you. Alternatives might have better insurance coverage or lower costs.

8. Learn more about patient assistance programs

Patient assistance programs (PAPs) offer free or low-cost medications to uninsured and low-income consumers. These programs, which primarily offer savings on brand-name medications, are usually run by private pharmaceutical companies or nonprofit organizations. You must meet certain qualifications and complete paperwork to receive savings from PAPs. However, some PAPs exclude Medicare recipients, so it’s important to review the program’s rules and requirements carefully.

9. Check state-funded resources

Depending on where you live, your state may offer programs to help you navigate prescription medication costs. A good place to start is your local Department of Aging. This U.S. Department of Health and Human Services office can help you find the best Medicare plan for the coverage you need.

Some states even have their own cost-saving programs for older adults. For example, Pennsylvania runs PACE and PACENET. These programs help eligible residents get prescription medications at reduced costs.

Alternatively, you can find out if your state has a State Pharmaceutical Assistance Program by using Medicare’s search tool. These programs are state-run and help qualifying residents pay for prescription medications.

10. Use a health savings account to pay for prescription medications

Although you can’t contribute to a health savings account (HSA) after enrolling in Medicare, you can still use any remaining funds in your account to pay for qualified medical expenses. An HSA allows you to use tax-free dollars to pay for eligible prescription medications. The money in your account does not expire so you can use your funds at any time to reduce your out-of-pocket medication costs.

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Frequently asked questions about Dacarbazine

Dacarbazine is most commonly used for Hodgkin’s lymphoma. It’s used as part of a chemotherapy combination regimen called ABVD, which is considered a first-choice treatment option for some people with Hodgkin’s lymphoma. Dacarbazine is also sometimes used off-label to treat a type of cancer called soft tissue sarcoma. This medication is FDA approved for treating metastatic melanoma as well. But the treatment options for melanoma have changed over the last few decades, and Dacarbazine is rarely used to treat melanoma now.

The most common side effect of Dacarbazine is having a low number of blood cells in your body. Dacarbazine can cause your white blood cell count to drop. Your white blood cells help your body fight infection. So when their levels are low, your body can't fight off an infection as well if you get sick. This medication can also cause you to have fewer red blood cells, leading to anemia and making you feel tired. In addition, Dacarbazine can cause you to have fewer platelets in your blood, which can put you at risk for bleeding. Your oncologist will keep track of your blood cell counts very closely while you’re taking Dacarbazine. Contact your care team if you have any unexpected bruising or bleeding or if you feel very tired. These can be signs that you have low blood cell counts.

Yes, Dacarbazine has a high risk of causing nausea and vomiting. Because of this high risk, it’s important to take medications to prevent nausea along with Dacarbazine. Your oncologist will prescribe anti-nausea medications that you can either take by mouth or get through your IV on the same day you get chemotherapy. Your oncologist will also prescribe anti-nausea medications for you to take at home if you need them in between treatments. Contact your care team if you have severe nausea that doesn’t get better with medications so they can help you manage this side effect.

How long you'll need to take Dacarbazine depends on many factors. Your oncologist will consider the type and stage of cancer you have, what other anti-cancer medications you're taking, how well treatment is working, and whether you’re having any bothersome or serious side effects. For example, how many treatments of Dacarbazine you get as part of the ABVD treatment plan for Hodgkin’s lymphoma depends on the stage of your cancer and how well you’re responding to therapy. You'll need PET scans done regularly so your oncologist can see how well treatment is working Make sure to follow up with your oncologist regularly to discuss your progress with Dacarbazine.

Some people who take Dacarbazine have experienced hair loss. Many of the medications often given with Dacarbazine cause hair loss, too. Typically, your hair will grow back after you stop chemotherapy. Let your care team know if you experience hair loss during treatment with Dacarbazine. They can discuss with you about ways to prevent more hair loss. Your care team can also provide resources about wigs, wraps, and scarves to help you cope with this side effect.

Talk with your oncologist if you’re pregnant or thinking about becoming pregnant. Dacarbazine hasn’t been well studied in human pregnancies. But animal studies show that the medication might cause harm to an unborn baby. Your oncologist will discuss with you about the risks of taking Dacarbazine during pregnancy.