The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
For preventing rejection after kidney, liver, or heart transplant: Side effects for transplant were reported in people taking a similar medication called cyclosporine (Sandimmune)
- Shaking (up to 55%)
- High blood pressure (up to 53%)
- Excessive hair growth on face, back, and chest (up to 45%)
- Kidney problems (up to 38%)
- Urinary tract infection (21%)
- Viral infections (16%)
- Overgrowth of gums (up to 16%)
- Nausea or vomiting (up to 10%)
For rheumatoid arthritis:
- Higher creatinine levels (possible kidney problem; up to 48%)
- Headache (25%)
- High blood pressure (25%)
- Nausea (18%)
- Stomach pain (15%)
- Excessive hair growth on face, back, and chest (15%)
- Diarrhea (13%)
- General pain (13%)
- Shaking (13%)
- Upper respiratory tract infection (13%)
- Muscle cramps (12%)
- Numbness, tingling, or burning in arms or legs (11%)
For psoriasis:
- High blood pressure (28%)
- Infection (25%)
- Higher creatinine levels (possible kidney problem; 20%)
- Headache (16%)
- High triglyceride levels (15%)
Less Common Side Effects
- Diarrhea
- Indigestion
- Swelling
- Dizziness
- Infections or flu-like symptoms
- Chest pain
- Mouth sores
- Cough
- Difficulty breathing
- Stuffy nose
- Flushed skin
- Rash
Cyclosporine Modified serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Serious infection: fever, difficulty breathing, muscle weakness, confusion, memory problems, loss of balance or coordination, not able to move
- Severely high blood pressure: headache, difficulty breathing, chest pain or pressure, blurred vision, fast heartbeat, nose bleed, confusion
- Kidney damage: urinating less, swelling in feet or legs, shortness of breath, tiredness, weakness, muscle cramps, nausea, vomiting, confusion
- Liver damage: yellowing of the skin or eyes (jaundice), stomach pain or swelling, loss of appetite, nausea, vomiting, dark urine, tiredness, weakness, confusion
- Brain damage: vision problems (e.g., blurred vision, double vision, loss of vision), loss of muscle control, movement problems, change in thoughts or behavior, seizures, loss of consciousness
Source: DailyMed
More on Cyclosporine Modified side effects
The following Cyclosporine Modified side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
More common
Abdominal or stomach pain or tenderness
back pain
black, tarry stools
blurred vision
chills
clay colored stools
cloudy urine
dark urine
decrease in urine output or decrease in urine-concentrating ability
decreased appetite
dizziness
drowsiness
headache
headache, severe and throbbing
loss of appetite
muscle spasms (tetany) or twitching
nervousness
painful or difficult urination
pounding in the ears
shakiness in the legs, arms, hands, or feet
shortness of breath
skin rash
slow or fast heartbeat
sores, ulcers, or white spots on the lips or in the mouth
swelling of the feet or lower legs
swollen glands
trembling or shaking of the hands or feet
unusual bleeding or bruising
unusual tiredness or weakness
yellow eyes or skin
Less common
Bleeding gums
blood in the urine
blood in the vomit
burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
convulsions
difficulty swallowing
pale skin
pinpoint red spots on the skin
puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
severe or continuing stomach pain
tightness in the chest
troubled breathing with exertion
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Abdominal or stomach discomfort
bleeding, tender, or enlarged gums
blemishes on the skin
increased hair growth, especially on the face
pain or tenderness around the eyes and cheekbones
stuffy or runny nose
Less common
Brittle fingernails
burning feeling in the chest or stomach
burning, dry, or itching eyes
continuing ringing or buzzing or other unexplained noise in the ears
cramps
discharge or excessive tearing
feeling of warmth
hearing loss
redness of the face, neck, arms, and occasionally, upper chest
redness, pain, swelling of the eye, eyelid, or inner lining of the eyelid
swelling of the breasts or breast soreness in both females and males
Rare
Blurred or loss of vision
discouragement
disturbed color perception
double vision
fear
feeling sad or empty
halos around lights
irritability
joint pain
loss of interest or pleasure
night blindness
overbright appearance of lights
tiredness
trouble concentrating
trouble sleeping
tunnel vision
unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
weakness
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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