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Ulcerative Colitis

Biologic Therapy to Treat Ulcerative Colitis: How These Medications Work

Brittany DoohanSanjai Sinha, MD
Written by Brittany Doohan | Reviewed by Sanjai Sinha, MD
Updated on November 10, 2025
Featuring Todd B. Linden, MDReviewed by Sanjai Sinha, MD | November 10, 2025

At any given time, about half of people with ulcerative colitis (UC) are in remission (a period of no symptoms), according to the Crohn’s and Colitis Foundation. A big part of that success can be attributed to the improvement of treatment options for UC.

One of the newer and remarkable treatment options is biologic therapy. Biologics get their name because they are made from natural life materials, as opposed to chemicals. Compared to other medications for inflammatory bowel diseases, biologics are able to target causes of inflammation more precisely.

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Brittany Doohan
Written by:
Brittany Doohan
Brittany Doohan was the Content Director at HealthiNation and is currently the Editorial Director at Medscape. Through her work with Medscape, she won a Silver Telly Award in May 2022 for "Sleepless Nation: A Public Health Epidemic — Episode 2: A Decade Without a Diagnosis." She has worked in health journalism and video production for more than 8 years, and loves the challenge of explaining complex topics in an easy-to-understand and creative way.
Sanjai Sinha, MD
Reviewed by:
Sanjai Sinha, MD
Sanjai Sinha, MD, is a board-certified physician with over 20 years of experience. He specializes in internal medicine.

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