The first treatment designed for multiple sclerosis (MS), an autoimmune disease that affects your central nervous system, became available for use less than 30 years ago. Now, luckily, there are now more than 10 different classes of medications available to treat it.
Today’s medications have improved in terms of their tolerability, safety, and effectiveness in treating MS. Many people with MS are able to find medication options that work for them (but treatment outcomes and side effects may vary for everyone).
Today, there are many effective treatments for MS called disease-modifying therapies. Some of the available medication formats include:
Injections
Oral medications
Infusions (intravenous)
Injections, pills, and infusions each have pros and cons. The right format for you may depend on several factors, such as your disease severity, your insurance/budget, your lifestyle, and the MS subtype you have.
Though they come in a few different forms, MS medications are increasingly grouped by how they’re working, as each medication class works a little bit differently.
Here are some different ways that MS medications work:
Altering the immune system (e.g. keeping immune cells in blood or lymph nodes)
Suppressing the immune system (e.g. reducing the number of white bloods or reducing the number of certain immune cells or their messengers)
Having so many options for MS medications improves the chances that you’ll find a medication that works for you. Today’s medications are also generally more effective at slowing the progression of MS.
It is normal to be worried when you get a diagnosis of MS, but advances in treatment generally help it to be more manageable. Remember, there’s no full cure for MS, but finding a good treatment plan and sticking to it should improve the chances of managing the condition.
“The good news is that in the modern era, MS is [often] highly treatable,” says Asaff Harel, MD, Neurologist at Lenox Hill Hospital in New York City. “And for a lot of people, really the goal is to bring [MS] into the background of their lives.”
Lublin, Fred. (2005). Journal of Neurology. History of modern multiple sclerosis therapy.
National Multiple Sclerosis Society. (N.D.). Medications.
Verdugo, R. M., et al. (2019). Adherence to disease-modifying treatments in patients with multiple sclerosis in Spain. Patient Preference and Adherence.
Yang, J. H., et al. (2022). Therapeutic advances in multiple sclerosis. Frontiers in Neurology.