Key takeaways:
Children with underactive thyroids (hypothyroidism) have trouble learning and growing. They may also experience constipation and get tired more easily than other children.
Children can be born with hypothyroidism (congenital hypothyroidism) or develop it during childhood or their teen years.
Children with hypothyroidism need treatment with thyroid hormone so they can grow, learn, and finish puberty.
You may have heard about hypothyroidism in adults. But did you know that children of all ages can have underactive thyroids, too? Here’s what hypothyroidism can look like in children, what causes it, and how it’s diagnosed and treated.
Hypothyroidism refers to an underactive thyroid. The thyroid gland is located in the front of the neck, and it’s part of the endocrine system. It makes the hormones thyroxine (T4) and triiodothyronine (T3), which play important roles in many body functions, including:
Growth
Energy metabolism
Brain development
Body temperature control
Thyroid disease is fairly common in adults, but it’s less common in children. But children can develop hypothyroidism at any age. They can also be born with hypothyroidism, a condition called “congenital hypothyroidism.”
The symptoms of an underactive thyroid are similar in children and adults. Children may experience:
Fatigue
Constipation
Mild weight gain
Cold sensitivity
Dry skin
Hair loss
Young babies with hypothyroidism may not have any symptoms. But babies may:
Seem very sleepy
Have trouble eating
Have a hoarse cry
Look like they have more jaundice (yellowing of the skin and eyes)
Be more floppy and have trouble holding their head up (decreased body tone)
Low thyroid levels will affect children differently depending on their age. Without treatment, children can develop long-lasting complications from hypothyroidism. Children who get started on treatment for hypothyroidism later are more likely to develop these complications.
Babies need thyroid hormone for brain growth and development. Children who are born with hypothyroidism can develop serious intellectual disabilities. They will also have trouble gaining weight and growing. To avoid these complications, babies need to start taking thyroid medication as soon as possible and definitely before they’re 2 weeks old.
Complications from congenital hypothyroidism are very severe. This is why babies are screened for the condition as part of their newborn screening. Newborn screening can identify congenital hypothyroidism when a child is only a few days old, long before they develop symptoms. That way they can start treatment early.
Children who develop acquired hypothyroidism typically have poor growth. This may not be obvious at first. But, over time, many parents notice that their child isn’t growing out of their clothes as fast as they used to. And healthcare providers often notice that children aren’t growing as fast as they should be for their age during routine checkups.
Children with acquired hypothyroidism also have trouble concentrating and learning. Some children may have trouble keeping up at school while others develop hyperactivity.
Teens who develop acquired hypothyroidism often have similar symptoms to adults. But since their brain is still growing and developing, they may also notice trouble with concentration and keeping up with schoolwork. Some teens have changes in their mood and seem more down than usual.
Thyroid hormone plays an important role in puberty and menstruation. Teens with underactive thyroids may not start puberty on time. If they’ve already started menstruating, teens with acquired hypothyroidism can develop irregular periods.
Experts divide the causes of childhood hypothyroidism into two broad categories — congenital and acquired. Let’s look at each condition.
Congenital hypothyroidism happens when a child is born with a thyroid gland that is not fully developed or doesn’t work properly. Most of the time, it’s not clear why babies are born without a fully developed thyroid.
Acquired hypothyroidism is hypothyroidism that starts when a child is older than 2 weeks. Acquired hypothyroidism is more common than congenital hypothyroidism.
The most common cause of acquired hypothyroidism in children and adolescents is Hashimoto’s thyroiditis. Hashimoto’s thyroiditis is an autoimmune condition in which the immune system attacks the thyroid.
Another cause of underactive thyroid is iodine deficiency. Iodine is an element that the thyroid uses to make thyroid hormone. Iodine deficiency isn’t common in the U.S. because iodine is added to salt. But in other parts of the world, iodine deficiency is a major cause of hypothyroidism.
Children can also develop hypothyroidism if the pituitary gland gets damaged or injured. The pituitary gland is a part of the brain that makes thyroid-stimulating hormone (TSH). TSH tells the thyroid gland when to make thyroid hormone. The pituitary gland can be injured if children need brain surgery or radiation. It can also get injured if children develop brain injuries or brain tumors.
A healthcare provider can diagnose hypothyroidism with a blood test that measures thyroid hormone and TSH.
Providers use a blood test to screen newborns for hypothyroidism right after birth. If a newborn screen detects a low thyroid level, babies can start treatment right away. Children and teens can have their thyroid levels tested if they have symptoms of hypothyroidism or if they are at higher risk of developing hypothyroidism.
Normal thyroid levels depend on a child’s age.
Age | Thyroid hormone (ng/dL) | TSH (mU/L) |
---|---|---|
1-4 days | 2.2-5.3 | 2.7-26.5 |
4-30 days | 0.9-3.4 | 1.2-13.1 |
1-12 months | 0.9-2.3 | 0.6-7.3 |
1-5 years | 0.8-1.8 | 0.7-6.6 |
6-10 years | 1.0-2.1 | 0.8-6.0 |
11-18 years | 0.8-1.9 | 0.6-5.8 |
These values may change a bit depending on the lab running the test.
If the results suggest hypothyroidism, children can start treatment with thyroid hormone. Treatment for hypothyroidism is pretty straightforward.
The medication levothyroxine (Synthroid) is the most common treatment choice. It’s a synthetic (human-made) version of thyroid hormone meant to replace what the body isn’t making. A child’s provider will select a dose based on their weight, then they’ll monitor TSH periodically to see if the dose needs to be adjusted. The goals are to get the hormones back in the normal range and improve the child’s symptoms.
Some children are able to stop taking thyroid medication over time.
About 5% to 15% of children with congenital hypothyroidism can stop taking thyroid hormone when they turn 3 years old. To determine this, the medication is stopped and the hormone levels are rechecked after about 1 month to see if the body is able to make the hormones on its own. That will help figure out if a child needs to continue taking thyroid medication or not.
Talk to your child’s healthcare provider if you think your child has hypothyroidism. Let the provider know which symptoms you’ve noticed. Your provider can order a blood test to check your child’s thyroid levels. If the levels are low, your child can start treatment right away.
Hypothyroidism isn’t as common in children as it is in adults. Thyroid hormone helps the brian grow and develop, and it also controls growth and puberty. That means children with underactive thyroids can face a host of serious symptoms like learning difficulties, trouble growing, and delayed puberty. Children who start thyroid hormone supplements quickly are able to avoid these complications.
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