Dry mouth medications treat dry mouth from conditions such as Sjögren's syndrome. They also treat dry mouth as a result of radiation therapy side effects. They work by stimulating saliva production or providing moisture to the mouth. Common classes include cholinergic agonists and saliva substitutes. Cholinergic agonists like pilocarpine (Salagen) and cevimeline (Evoxac) are usually taken as oral pills. Saliva substitutes, such as Xylitol (Xylmelts), Aquoral (oxidized glycerol triesters), and Neutrasal (calcium phosphate) come in various forms like lozenges, sprays, and rinses. These options help keep your mouth moist and comfortable.