Medications for anticoagulant-reversal are used to treat bleeding complications, reverse the effects of blood thinners, and manage emergency situations involving anticoagulants. They work by counteracting the effects of anticoagulants, helping your blood to clot more effectively. A common class is reversal agents. Reversal agents like idarucizumab (Praxbind), andexanet alfa (Andexxa), and prothrombin complex concentrate (Kcentra) are usually given as injections. Protamine is another injectable option used to reverse the effects of heparin. These medications provide different ways to quickly manage bleeding and restore normal clotting.