Zyclara vs. Imiquimod for HPV and Actinic Keratosis: Important Differences and Potential Risks.

Imiquimod

(Zyclara)

Get free coupons

Save more on select medications with GoodRx Companion.

imiquimod 5%

Get free coupons

Save more on select medications with GoodRx Companion.

Summary for Zyclara

Prescription only

Imiquimod 2.5% and 3.75% cream (Zyclara) is a prescription topical medication. It's used to treat actinic keratosis on the face or scalp in adults. The 3.75% version can also treat genital and anal warts in people ages 12 years and older. Imiquimod (Zyclara) is applied to the affected areas of the skin once each night. How long you'll use the cream depends on the condition being treated. Common side effects are skin redness, scabbing, and crusting.

Indications for Zyclara

Actinic keratosis on the face or scalp in adults - 2.5% and 3.75% cream
Genital and anal warts in adults and children ages 12 years and older - 3.75% cream only

Pros and Cons for Zyclara

Pros

Applied directly onto the affected areas
Can use at home

Cons

Need to remember to wash off the next morning
Can cause skin irritation where it's applied

Common Side Effects for Zyclara

Skin redness
Scabbing or crusting
Flaky, scaly, or dry skin
Swollen skin
Ulcer or sore on the skin
Oozing from the skin

Warnings for Zyclara

Local skin reactions
Minimize or avoid ultraviolet (UV) light
Flu-like symptoms

Summary for Imiquimod

Prescription only

Imiquimod 5% cream (Aldara) is a prescription cream that's applied to the skin. It's used to treat actinic keratosis on the face or scalp and a type of skin cancer called superficial basal cell carcinoma in adults. It also treats genital and anal warts in people ages 12 years and older. Imiquimod 5% is usually applied onto the affected skin several times a week. The most common side effects are skin itching, irritation, and burning.

Indications for Imiquimod

Actinic keratosis on the face or scalp in adults
Superficial basal cell carcinoma in adults
Genital and anal warts in adults and children ages 12 years and older

Pros and Cons for Imiquimod

Pros

Applied directly onto the affected areas
Can use at home
Can treat areas of damaged skin without a procedure (for actinic keratosis or basal cell carcinoma)

Cons

Need to remember to wash off the next morning
Can cause skin irritation where it's applied
Treatment can take several weeks or months

Common Side Effects for Imiquimod

Skin redness
Flaky, scaly, or dry skin
Scabbing or crusting
Swollen skin
Ulcer or sore on the skin
Oozing from the skin

Warnings for Imiquimod

Local skin reactions
Minimize or avoid ultraviolet (UV) light
Flu-like symptoms

Prices with our coupons for Zyclara vs. Imiquimod

Imiquimod1 carton / 28 packets of 3.75%

$340.30$891.87

Get free coupons

More Information

Imiquimod24 packets / 5%

$28.64$219.56

Get free coupons

More Information

Browse medications by letter

Show All

Browse prescription and over-the-counter medications from A to Z, compare drug prices, and start saving.

Compare
Zyclara vs. Imiquimod

Imiquimod

imiquimod 5%

Summary for Zyclara

Indications for Zyclara

Pros and Cons for Zyclara

Pros

Cons

Common Side Effects for Zyclara

Warnings for Zyclara

Summary for Imiquimod

Indications for Imiquimod

Pros and Cons for Imiquimod

Pros

Cons

Common Side Effects for Imiquimod

Warnings for Imiquimod

Prices with our coupons for Zyclara vs. Imiquimod

Browse medications by letter

Good news for your inbox

Imiquimod

imiquimod 5%

Summary for Zyclara

Indications for Zyclara

Pros and Cons for Zyclara

Pros

Cons

Common Side Effects for Zyclara

Warnings for Zyclara

Summary for Imiquimod

Indications for Imiquimod

Pros and Cons for Imiquimod

Pros

Cons

Common Side Effects for Imiquimod

Warnings for Imiquimod