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Typhim Vi vs. Vivotif

Typhim Vi is an inactivated vaccine that helps protect people ages 2 and older from typhoid fever, a life-threatening bacterial infection. The vaccine isn't routine for everyone — it's only recommended for certain people at high risk of coming into contact with the typhoid bacteria. It's given as a single injection into the muscle to provide protection for 2 years. The most common side effects are pain and tenderness at the injection site.

• Prevention of typhoid fever in adults and children 2 years or older

• Tenderness at injection site (up to 98%)
• Pain at injection site (up to 41%)
• Feeling unwell (up to 24%)
• Headache (up to 20%)
• Hardening of skin at injection site (up to 15%)
• Nausea (up to 8%)
• Muscle pain (up to 7%)
• Redness at injection site (up to 5%)

• Avoid contaminated food and water
• Severe allergic reactions
• Fainting
• Weakened immune system might affect vaccine response

Vivotif is a prescription live-attenuated vaccine that's used to prevent typhoid fever in people ages 6 years and older. It comes as a capsule that's taken by mouth on an empty stomach every other day for 4 doses total. Vivotif isn't a routine vaccine for everyone; it's only recommended for certain people who are traveling to a place where typhoid is common or for people who are at high risk of coming into contact with Salmonella typhi, the bacteria that causes typhoid fever. Side effects of this vaccine include stomach pain, nausea, and headache.

• Prevention of typhoid fever in people ages 6 years or older

• Stomach pain (6%)
• Nausea (6%)
• Headache (5%)

• Maintain necessary precautions
• Interactions with other medications
• Not recommended for people with weakened immune systems