Synalar vs. Fluocinonide for Eczema and Psoriasis: Important Differences and Potential Risks.

Fluocinolone

Fluocinonide

Summary for Synalar

Prescription only

Fluocinolone, also known by its brand name, Synalar, is a prescription topical steroid used to treat many inflammatory and itchy skin conditions, such as psoriasis or eczema. It comes as a lower-cost generic cream, ointment, and topical solution. The medication is typically applied to the skin two to four times per day, depending on the condition. Side effects aren't common, but can include skin burning and irritation.

Indications for Synalar

Inflammatory and itchy skin conditions

Pros and Cons for Synalar

Pros

Can treat various inflammatory and itchy skin conditions
Available in different forms (cream, ointment, topical solution)
Available as a lower-cost generic

Cons

Needs to be applied two to four times per day
Not meant for long-term use
Young children might be at higher risk for side effects

Common Side Effects for Synalar

Burning
Itching
Irritation

Warnings for Synalar

Altered stress hormone levels
Skin thinning

Summary for Fluocinonide

Prescription only

Fluocinonide is a strong topical steroid that's applied on the skin. It treats rashes and skin irritation in adults and children. The medication comes as a cream, ointment, gel, and topical solution. All topical forms come as generics, but the cream is also available under the brand name Vanos. You apply fluocinonide to the affected skin one to four times a day, depending on the formulation. This medication isn't meant for long-term use because of potential side effects like skin thinning and changes in skin color.

Indications for Fluocinonide

Inflammatory and itchy skin problems, such as rash, eczema, and psoriasis

Pros and Cons for Fluocinonide

Pros

Treats a wide range of skin problems that are itchy or inflamed
Has few side effects when used for short periods of time
Many formulation options available (cream, gel, ointment, or topical solution)

Cons

Might have to apply it up to 4 times a day (depends on the strength and your symptoms)
Might not be the best option for treating sensitive areas like the face, underarms, or groin
Not meant for long-term use