Key takeaways
Suprep (sodium sulfate/potassium sulfate/magnesium sulfate) and magnesium citrate are both used to help with bowel movements, but they have different uses and availability. Suprep is a prescription-only osmotic laxative used specifically for colon cleansing before a colonoscopy, while magnesium citrate is an over-the-counter saline laxative used for occasional constipation. Suprep requires a two-dose regimen taken the night before and the morning of the procedure, whereas magnesium citrate can produce a bowel movement within 30 minutes to 6 hours after a single dose. Suprep is not recommended for people with kidney problems due to the risk of fluid and electrolyte imbalance, and it can cause side effects like stomach discomfort and bloating. Magnesium citrate also should be avoided by those with kidney issues and can cause nausea and diarrhea. Suprep is generally considered likely to cause bloating side effects compared to some other bowel preps. Magnesium citrate is more accessible since it’s available without a prescription and comes in various flavors.
