Head-to-head comparisons of medication uses, side effects, warnings, and more.
Dayquil (acetaminophen/dextromethorphan/phenylephrine) and Advil Congestion Relief (ibuprofen/phenylephrine) are both over-the-counter medications used to relieve symptoms of the common cold and flu, such as nasal congestion and minor aches. However, they belong to different medication classes. Dayquil combines an analgesic, cough suppressant, and econgestant, while Advil Congestion Relief combines a nonsteroidal anti-inflammatory drug (NSAID) and a decongestant. You can take Dayquil every 4 hours, but you should not exceed the maximum daily dose, which varies by brand. IAdvil Congestion Relief is also taken every 4 hours, with a maximum of 6 tablets in 24 hours. Common Dayquil side effects include stomach upset and nervousness, while Advil Congestion Relief may cause dizziness, stomach upset, and heartburn. Both medications should be used cautiously with other medications, especially those affecting the liver or containing similar ingredients.
Dayquil Cold and Flu is a combination of three active ingredients: acetaminophen (an analgesic), dextromethorphan (a cough suppressant), and phenylephrine (a decongestant). Dayquil Cold and Flu helps treat symptoms from the common cold and flu in adults and children. It can relieve stuffy nose, cough, sore throat, headache, aches, and fever. Besides Dayquil Cold and Flu, this medication is available under many other brand names and as a generic. It's available as pills and a liquid that's typically taken every 4 hours. Side effects aren't common but can include stomach upset and nervousness.
Ibuprofen/phenylephrine is a combination of two medications used to treat pain and congestion, which are symptoms of the common cold or flu. It's available over the counter (OTC) and as a lower-cost generic medication. Using it longer than recommended can put you at risk for side effects such as stomach bleeds.
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