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Compare Dayquil vs. Advil Congestion

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Dayquil (acetaminophen/dextromethorphan/phenylephrine) and Advil Congestion Relief (ibuprofen/phenylephrine) are both over-the-counter medications used to relieve symptoms of the common cold and flu, such as nasal congestion and minor aches. However, they belong to different medication classes. Dayquil combines an analgesic, cough suppressant, and econgestant, while Advil Congestion Relief combines a nonsteroidal anti-inflammatory drug (NSAID) and a decongestant. You can take Dayquil every 4 hours, but you should not exceed the maximum daily dose, which varies by brand. IAdvil Congestion Relief is also taken every 4 hours, with a maximum of 6 tablets in 24 hours. Common Dayquil side effects include stomach upset and nervousness, while Advil Congestion Relief may cause dizziness, stomach upset, and heartburn. Both medications should be used cautiously with other medications, especially those affecting the liver or containing similar ingredients.

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