Seysara vs. Vibramycin for Acne: Important Differences and Potential Risks.

Seysara

(sarecycline)

doxycycline hyclate

Summary for Seysara

Prescription only

Seysara (sarecycline) is a tetracycline antibiotic that treats moderate-to-severe non-nodular acne, such as whiteheads, blackheads, and papules. It can be prescribed for adults and children ages 9 years and older. Seysara (sarecycline) is a tablet that's taken by mouth once per day for up to 3 months. Most people don't experience side effects from Seysara (sarecycline), but a few have reported nausea.

Indications for Seysara

Moderate-to severe-non-nodular acne (whiteheads, blackheads, papules, pustules, and cysts) in people ages 9 years and older

Pros and Cons for Seysara

Pros

Most people taking Seysara (sarecycline) had almost clear or clear skin after 3 months of treatment
Tends to have less side effects compared to other tetracycline antibiotics for acne
Taken by mouth once a day
Can be taken with or without food

Cons

Can make you more sensitive to the sun and cause more painful sunburns
Shouldn’t be used during pregnancy
Not recommended for children 8 years and younger because of risk of teeth discoloration and slow bone growth
Can cause fertility problems in males who are trying to have a child

Common Side Effects for Seysara

Nausea (3%)

Warnings for Seysara

Not for use during pregnancy or nursing
Infectious diarrhea
Dizziness and light-headedness
High blood pressure in the brain
Sun and light sensitivity
Drug-resistant infections

Summary for Vibramycin

Prescription only

Doxycycline hyclate is an antibiotic that treats many conditions, including acne, chlamydia, sinus infection, and urinary tract infection (UTI). It's taken by mouth, typically once or twice daily. It comes as capsules, tablets, and a liquid syrup. Side effects of doxycycline hyclate include stomach upset, nausea, and vomiting.

Indications for Vibramycin

Doxycycline hyclate is used to prevent malaria due to the parasite Plasmodium falciparum and to treat many different infections caused by bacteria. Some examples include:

Respiratory tract infections, including in the nose, throat, and lungs
Infections caused by ticks, mites, or fleas (Rocky Mountain spotted fever or typhus fever)
Sexually-transmitted infections (STIs) like chlamydia, gonorrhea, chancroid, and syphilis
Lyme disease
Urinary tract infections (UTIs)
Severe acne
Anthrax
Plague
Cholera

Pros and Cons for Vibramycin

Pros

Good alternative for some infections if you're allergic to penicillins
Treats many different infections, including severe acne and sexually transmitted infections (STIs) like chlamydia
Available as a liquid for those who have trouble swallowing pills
Likely safe for people who have kidney problems