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Compare Seroquel vs. Aristada

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Quetiapine (Seroquel) and Aristada (aripiprazole lauroxil) are both atypical antipsychotics used to treat schizophrenia, but they have some key differences. Quetiapine can also treat bipolar disorder and depression. Quetiapine is available in both immediate-release and extended-release oral tablets, while Aristada is a long-acting injection given by a healthcare professional. Aristada is administered every 1 to 2 months, making it a good option for those who have trouble taking daily medications, while quetiapine needs to be taken 2 to 3 times a day. Both medications can cause high blood sugar and weight gain, but Aristada has fewer side effects overall. Quetiapine is available as a lower-cost generic, but Aristada is only available as a brand medication, which can make it more expensive.

  • Quetiapine (Seroquel)
    Aristada (aripiprazole lauroxil)
  • Quetiapine (Seroquel)
    Aristada (aripiprazole lauroxil)

  • Summary of Seroquel vs. Aristada

    Summary for Atypical antipsychotic
    Prescription only

    Quetiapine (Seroquel) is an atypical antipsychotic. It's used to treat mental health problems like schizophrenia and bipolar disorder. This medication comes as an immediate-release tablet (Seroquel) that's taken by mouth usually twice a day. There's also an extended-release tablet (Seroquel XR) that's taken once a day. The specific dosage depends on how well it's helping your mood, thoughts, and behaviors. Side effects can include sleepiness, headache, and possible weight gain. There are brand-name and generic versions of this medication.

    Summary for Atypical antipsychotic
    Prescription only

    Aristada (aripiprazole lauroxil) is used to improve mood, thoughts, and behaviors in adults who have schizophrenia. It's a long-acting medication that's injected into your muscle every 1 to 2 months by your healthcare provider. It's only used in people who can tolerate Abilify (aripiprazole) oral tablets.

  • Indications of Seroquel vs. Aristada

    Indications for
    •Schizophrenia in adults and children ages 13 years and older
    •Bipolar disorder in adults and certain children ages 10 years and older
    •Depression in adults, as an add-on to other antidepressants - extended-release only
    Indications for
    •Schizophrenia

  • Pros and Cons of Seroquel vs. Aristada

    Pros and Const for Atypical antipsychotic
    Pros
    •Taken by mouth
    •Might notice an improvement in your symptoms in as early as a week of starting the medication
    •Available in both short-acting and long-acting tablets
    Cons
    •Might cause weight gain
    •Can raise your blood sugar and cholesterol levels
    •Not recommended for older adults who have dementia-related psychosis
    Pros and Const for Atypical antipsychotic
    Pros
    •Can be given up to once every 2 months
    •Good option for people who have a hard time taking medications by mouth
    •Has fewer side effects compared to some other antipsychotic medications
    •Patient assistance programs are available to help lower the cost
    Cons
    •Can cause high blood sugar and weight gain
    •Must be injected in the muscle at your healthcare provider's office
    •Can cause soreness or pain at the injection site
    •Not recommended for use during pregnancy or breastfeeding
    •Can be expensive because it's only available as a brand medication

  • Common Side Effects of Seroquel vs. Aristada

    Common Side Effects for

    Immediate-release tablets:

    •Headache (21%)
    •Agitation (20%)
    •Sleepiness (18%)
    •Dizziness (11%)
    •Dry mouth (9%)
    •Constipation (8%)
    •Pain (7%)
    •Fast heart rate (6%)
    •Vomiting (6%)

    Extended-release tablets:

    •Sleepiness (25%)
    •Dry mouth (12%)
    •Dizziness (10%)
    •Trouble controlling muscle movements (8%)
    •Low blood pressure when standing up (7%)
    •Constipation (6%)
    Common Side Effects for
    •Restlessness (11%)
    •Unusual and uncontrollable muscle movements or muscle spasms (5-7%)

  • Warnings of Seroquel vs. Aristada

    Common Side Effects for
    •Higher risk of death and stroke in older people with dementia-related psychosis
    •Risk of suicidal thoughts and behavior
    •Neuroleptic malignant syndrome
    •High blood sugar, high cholesterol, and weight gain
    •Trouble controlling muscle movements (tardive dyskinesia)
    •Changes in blood pressure
    •Risk of falls
    •Risk of infection (due to low white blood cell counts)
    •Possible changes in heart rhythm
    •Seizures
    •Hypothyroidism (low thyroid hormone)
    •High prolactin levels
    •Feeling very sleepy and having trouble concentrating
    Common Side Effects for
    •Higher risk of death in older adults with dementia-related psychosis
    •Neuroleptic malignant syndrome (NMS)
    •Difficulty controlling muscle movements (tardive dyskinesia)
    •High blood sugar, high cholesterol, and weight gain
    •Impulsive behavior
    •Higher risk of falls
    •Higher risk of infections
    •Seizures

  • Prices with our coupons for Seroquel vs. Aristada

    Learn more about Quetiapine
    Learn more about Aristada

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